Ultra-small gadolinium oxide nanoparticles to image brain cancer cells in vivo with MRI

2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
Luc Faucher ◽  
Andrée-Anne Guay-Bégin ◽  
Jean Lagueux ◽  
Marie-France Côté ◽  
Éric Petitclerc ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Brain Cancer ◽  
Gadolinium Oxide ◽  
Oxide Nanoparticles ◽  
Gadolinium Oxide Nanoparticles

Hybrid Gadolinium Oxide Nanoparticles:  Multimodal Contrast Agents for in Vivo Imaging

2007 ◽  
Vol 129 (16) ◽  
pp. 5076-5084 ◽  
Author(s):  
Jean-Luc Bridot ◽  
Anne-Charlotte Faure ◽  
Sophie Laurent ◽  
Charlotte Rivière ◽  
Claire Billotey ◽  
...  
Keyword(s):  
Contrast Agents ◽  
In Vivo Imaging ◽  
Gadolinium Oxide ◽  
Oxide Nanoparticles ◽  
Gadolinium Oxide Nanoparticles

scholarly journals In vivo neutron capture therapy of cancer using ultrasmall gadolinium oxide nanoparticles with cancer-targeting ability

RSC Advances ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 865-874 ◽  
Author(s):  
Son Long Ho ◽  
Garam Choi ◽  
Huan Yue ◽  
Hee-Kyung Kim ◽  
Ki-Hye Jung ◽  
...  
Keyword(s):  
Neutron Capture ◽  
Gadolinium Oxide ◽  
Growth Suppression ◽  
Cancer Growth ◽  
Oxide Nanoparticles ◽  
Cancer Targeting ◽  
Neutron Capture Therapy ◽  
Targeting Ability ◽  
Gadolinium Oxide Nanoparticles

A cancer growth suppression was observed due to the GdNCT effects of the RGD-PAA-UGNPs.

Ligand-size dependent water proton relaxivities in ultrasmall gadolinium oxide nanoparticles and in vivo T1 MR images in a 1.5 T MR field

2014 ◽  
Vol 16 (37) ◽  
pp. 19866-19873 ◽  
Author(s):  
Cho Rong Kim ◽  
Jong Su Baeck ◽  
Yongmin Chang ◽  
Ji Eun Bae ◽  
Kwon Seok Chae ◽  
...  
Keyword(s):  
Gadolinium Oxide ◽  
Water Proton ◽  
Oxide Nanoparticles ◽  
Mr Images ◽  
Size Dependent ◽  
Gadolinium Oxide Nanoparticles

Ligand-size dependent r1 and r2 values of Gd2O3 nanoparticles and in vivo T1 MR images were obtained.

scholarly journals Gadolinium oxide nanoparticles enhance the cytotoxicity of chemotherapeutic drugs by blocking autophagic flux in cancer cells

2019 ◽  
Author(s):  
Tianyu Zhang ◽  
Cheng Zhong ◽  
Zhixiong Xie
Keyword(s):  
Cancer Cells ◽  
Chemotherapy Resistance ◽  
Gadolinium Oxide ◽  
Oxide Nanoparticles ◽  
Autophagic Flux ◽  
Dependent Manner ◽  
Chemotherapy Drugs ◽  
Cancer Diagnosis And Therapy ◽  
Dose Dependent ◽  
Gadolinium Oxide Nanoparticles

Abstract During chemotherapy, drugs can damage cancer cells’ DNA and cytomembrane structure, and then induce cell death. However, autophagy can increase the chemotherapy resistance of cancer cells, reducing the effect of chemotherapy. We found that gadolinium oxide nanoparticles (Gd2O3 NPs), which have great potential for use as a contrast agent in magnetic resonance imaging, could block the late stage of autophagic flux in a dose-dependent manner and then cause autophagosome accumulation in HeLa cells. When co-treated with 8 μg/mL Gd2O3 NPs and 5 μg/mL cisplatin, the number of dead cancer cells increased by about 20% compared with cisplatin alone. We observed the same phenomenon in cisplatin-resistant COC1/DDP cells. Thus, Gd2O3 NPs have significant potential for use in both cancer diagnosis and therapy.

Various ligand-coated ultrasmall gadolinium-oxide nanoparticles: Water proton relaxivity and in-vivo T1 MR image

2015 ◽  
Vol 66 (8) ◽  
pp. 1295-1302 ◽  
Author(s):  
Ja Young Park ◽  
Sung June Kim ◽  
Gang Ho Lee ◽  
Seonguk Jin ◽  
Yongmin Chang ◽  
...  
Keyword(s):  
Gadolinium Oxide ◽  
Water Proton ◽  
Oxide Nanoparticles ◽  
Mr Image ◽  
Gadolinium Oxide Nanoparticles

Multi-Luminescent Hybrid Gadolinium Oxide Nanoparticles as Potential Cell Labeling

2009 ◽  
Vol 9 (10) ◽  
pp. 5717-5725 ◽  
Author(s):  
J. Fizet ◽  
C. Rivière ◽  
J.-L. Bridot ◽  
N. Charvet ◽  
C. Louis ◽  
...  
Keyword(s):  
Gadolinium Oxide ◽  
Cell Labeling ◽  
Oxide Nanoparticles ◽  
Gadolinium Oxide Nanoparticles
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