Ligand-size dependent water proton relaxivities in ultrasmall gadolinium oxide nanoparticles and in vivo T1 MR images in a 1.5 T MR field

2014 ◽  
Vol 16 (37) ◽  
pp. 19866-19873 ◽  
Author(s):  
Cho Rong Kim ◽  
Jong Su Baeck ◽  
Yongmin Chang ◽  
Ji Eun Bae ◽  
Kwon Seok Chae ◽  
...  
Keyword(s):  
Gadolinium Oxide ◽  
Water Proton ◽  
Oxide Nanoparticles ◽  
Mr Images ◽  
Size Dependent ◽  
Gadolinium Oxide Nanoparticles

Ligand-size dependent r1 and r2 values of Gd2O3 nanoparticles and in vivo T1 MR images were obtained.

Various ligand-coated ultrasmall gadolinium-oxide nanoparticles: Water proton relaxivity and in-vivo T1 MR image

2015 ◽  
Vol 66 (8) ◽  
pp. 1295-1302 ◽  
Author(s):  
Ja Young Park ◽  
Sung June Kim ◽  
Gang Ho Lee ◽  
Seonguk Jin ◽  
Yongmin Chang ◽  
...  
Keyword(s):  
Gadolinium Oxide ◽  
Water Proton ◽  
Oxide Nanoparticles ◽  
Mr Image ◽  
Gadolinium Oxide Nanoparticles

Ultra-small gadolinium oxide nanoparticles to image brain cancer cells in vivo with MRI

2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
Luc Faucher ◽  
Andrée-Anne Guay-Bégin ◽  
Jean Lagueux ◽  
Marie-France Côté ◽  
Éric Petitclerc ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Brain Cancer ◽  
Gadolinium Oxide ◽  
Oxide Nanoparticles ◽  
Gadolinium Oxide Nanoparticles

Hybrid Gadolinium Oxide Nanoparticles:  Multimodal Contrast Agents for in Vivo Imaging

2007 ◽  
Vol 129 (16) ◽  
pp. 5076-5084 ◽  
Author(s):  
Jean-Luc Bridot ◽  
Anne-Charlotte Faure ◽  
Sophie Laurent ◽  
Charlotte Rivière ◽  
Claire Billotey ◽  
...  
Keyword(s):  
Contrast Agents ◽  
In Vivo Imaging ◽  
Gadolinium Oxide ◽  
Oxide Nanoparticles ◽  
Gadolinium Oxide Nanoparticles

Longitudinal Water Proton Relaxivity and In Vivo T1 MR Images of Mixed Zn(II)/Gd(III) Oxide Nanoparticles

2017 ◽  
Vol 17 (4) ◽  
pp. 2423-2430
Author(s):  
Tirusew Tegafaw ◽  
Bardul Alam Bony ◽  
Wenlong Xu ◽  
Hyunsil Cha ◽  
Yongmin Chang ◽  
...  
Keyword(s):  
Water Proton ◽  
Oxide Nanoparticles ◽  
Mr Images

scholarly journals In vivo neutron capture therapy of cancer using ultrasmall gadolinium oxide nanoparticles with cancer-targeting ability

RSC Advances ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 865-874 ◽  
Author(s):  
Son Long Ho ◽  
Garam Choi ◽  
Huan Yue ◽  
Hee-Kyung Kim ◽  
Ki-Hye Jung ◽  
...  
Keyword(s):  
Neutron Capture ◽  
Gadolinium Oxide ◽  
Growth Suppression ◽  
Cancer Growth ◽  
Oxide Nanoparticles ◽  
Cancer Targeting ◽  
Neutron Capture Therapy ◽  
Targeting Ability ◽  
Gadolinium Oxide Nanoparticles

A cancer growth suppression was observed due to the GdNCT effects of the RGD-PAA-UGNPs.

Chitosan Oligosaccharide Lactate-Coated Ultrasmall Gadolinium Oxide Nanoparticles: Synthesis, In Vitro Cytotoxicity, and Relaxometric Properties

2021 ◽  
Vol 21 (8) ◽  
pp. 4145-4150
Author(s):  
Mohammad Yaseen Ahmad ◽  
Md. Wasi Ahmad ◽  
Huan Yue ◽  
Son Long Ho ◽  
Hyunsil Cha ◽  
...  
Keyword(s):  
Gadolinium Oxide ◽  
Mri Contrast Agents ◽  
Proton Spin ◽  
Mri Contrast Agent ◽  
Water Proton ◽  
Oxide Nanoparticles ◽  
Chitosan Oligosaccharide ◽  
Mri Contrast ◽  
Gadolinium Oxide Nanoparticles

In this study, hydrophilic and biocompatible chitosan oligosaccharide lactate (COL)-coated ultra-small gadolinium oxide nanoparticles (NPs) were synthesized through a one-pot polyol method and characterized by various experimental techniques. The In Vitro cellular cytotoxicity assay indicated that the COL-coated gadolinium oxide NPs were non-toxic up to 500 μM Gd. In addition, their water proton spin relaxivities (i.e., r1 and r2) were estimated to be 13.0 and 27.0 s−1mM−1, respectively, which are higher than those of commercial magnetic resonance imaging (MRI) contrast agents. The application potential of the solution sample as a T1 MRI contrast agent was demonstrated In Vitro by measuring map images in which dose-dependent contrast enhancements were observed.

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