ABO blood group is a potent risk factor for venous thromboembolism in patients with malignant gliomas

Cancer ◽  
2004 ◽  
Vol 100 (8) ◽  
pp. 1717-1723 ◽  
Author(s):  
Michael B. Streiff ◽  
Jodi Segal ◽  
Stuart A. Grossman ◽  
Thomas S. Kickler ◽  
Edward G. Weir
Keyword(s):  
Risk Factor ◽  
Venous Thromboembolism ◽  
Blood Group ◽  
Malignant Gliomas ◽  
Abo Blood Group

ABO blood group as a potential risk factor for venous thromboembolism in acutely injured patients

2011 ◽  
Vol 105 (01) ◽  
pp. 5-13 ◽  
Author(s):  
Sarah Muellner ◽  
Elliott Haut ◽  
Michael Streiff ◽  
John Holcomb ◽  
Bryan Cotton
Keyword(s):  
Risk Factor ◽  
Venous Thromboembolism ◽  
Blood Group ◽  
Abo Blood Group ◽  
Trauma Patients ◽  
Major Health Problem ◽  
Increase Risk ◽  
Significant Burden ◽  
Injured Patients ◽  
Von Willebrand

SummaryVenous thromboembolism (VTE) is a major health problem that results in a significant burden on hospitals and patients. VTE screening and prophylaxis protocols in trauma patients vary significantly among hospitals and providers. In addition, many patients develop VTE even in the absence of “high-risk” categories. Therefore, more research is needed to better understand and prevent VTE in these patients. ABO blood group has long been recognised as a risk factor for VTE, but its contribution to VTE risk in the trauma setting is poorly studied. This paper reviews the literature describing the link between ABO blood group and VTE risk and the implications for VTE screening and prophylaxis in trauma patients. The effect of ABO blood groups are genotype-dependent – in most populations the A1 allele and the B allele increase risk while A2, O1, and O2 decrease risk of VTE. ABO group is a major determinant of plasma von Willebrand factor (vWF) and factor VIII levels, thereby (partially) mediating the effects of ABO blood group on VTE susceptibility. In addition, ABH antigens alter plasma levels of vWF via clearance mechanisms, which are in turn mediated by ADAMTS13. ABO blood group is a risk factor for VTE that warrants further investigation in trauma patients.

scholarly journals The influence of ABO blood group on mortality in major trauma

2019 ◽  
Vol 11 (4) ◽  
Author(s):  
Uwe Hamsen ◽  
André Nohl ◽  
Andreas Baumann ◽  
Rolf Lefering ◽  
Laila Boutakmant ◽  
...  
Keyword(s):  
Risk Factor ◽  
Injury Severity Score ◽  
Blood Group ◽  
Severity Score ◽  
Injury Severity ◽  
Severe Bleeding ◽  
Abo Blood Group ◽  
Thromboembolic Events ◽  
Multiple Injured ◽  
The Impact

ABO blood group has a profound influence on hemostasis as it is a major determinant of plasma levels of von Willebrand Factor. In vitro studies suggest that blood group O is a risk factor for increased severe bleeding while blood group non-O is a risk factor for thromboembolic events. Yet, the impact of ABO blood group outcome after multiple trauma is unknown. Retrospective multicenter case-control study from three level-1 trauma centers in Germany from 2012-2015. Inclusion criteria were severe trauma with an Injury severity score ≥9 and admission to an intensive care unit. 1281 patients (69.5% male) were included. Mean Injury Severity Score (ISS) was 21.1±12.4; mean age was 50.2±22.4 years. Distribution of blood groups was: O: 37.4%; A: 44%, B: 12.7 and AB: 5.8%. Hospital mortality depending on blood group was 9.7 (A), 10.4 (B), 6.8 (AB) and 12.7 (O) %. Multivariant logistic regression for mortality revealed an Odds ratio of 0.79 (A), 0.60 (B) and 0.54 (AB) without statistical significance (P=0.35 (A), 0.17 (B), 0.33 (AB)). Thromboembolic events (blood group O vs. others) occurred in 2.8 (O) vs. 3.3 (others) %, P=0.619. In this retrospective study on 1281 multiple injured patients, no relevant influence of ABO blood group on hemorrhage, thromboembolic events and mortality could be found.

PO-111 Blood group B is a potent risk factor for venous thromboembolism in glioblastoma multiforme

2021 ◽  
Vol 200 ◽  
pp. S80
Author(s):  
K.M. Heenkenda ◽  
A. Malmström ◽  
M. Lysiak ◽  
M. Mudaisi ◽  
C. Bratthäll ◽  
...  
Keyword(s):  
Risk Factor ◽  
Venous Thromboembolism ◽  
Glioblastoma Multiforme ◽  
Blood Group ◽  
Group B

Recurrent venous thromboembolism: a role for ABO blood group?

2013 ◽  
Vol 110 (12) ◽  
pp. 1110-1111 ◽  
Author(s):  
Massimo Franchini ◽  
Francesco Dentali
Keyword(s):  
Venous Thromboembolism ◽  
Blood Group ◽  
Abo Blood Group ◽  
Recurrent Venous Thromboembolism

scholarly journals Relationship between ABO blood group and breast cancer at AL-Nassyria city / Iraq

2008 ◽  
pp. 26-29
Keyword(s):  
Breast Cancer ◽  
Risk Factor ◽  
Cancer Patients ◽  
Blood Group ◽  
High Frequency ◽  
Blood Groups ◽  
Blood Type ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Control Samples

The current study included 200 patients with breast cancer that resemble to patient samples were collected from AL-Nassyria hospital also 279 samples as control which was collected from blood bank at ALNassiryia province . The study attempted to correlate ABO blood group with incidence to breast cancer .The results shown that type A of ABO blood group high frequency then followed by type O with in AL-Nassyria region also the results reported that A, B, O and AB blood groups frequencies of patient samples percentage were 60%, 20%, 10% and 10% respectively as well as the ABO blood groups frequencies of control samples percentage were 26%, 28%,38% and 8% respectively. The results observed there is high significant differences between ABO blood group frequencies of cancer patients and ABO blood group frequencies of control samples .The results indicated that the blood type should be considered one of risk factor as well as regarded as preclinical marker.

scholarly journals ABO blood group as a risk factor for tuberculosis: A network meta-analysis

2021 ◽  
Vol 104 ◽  
pp. 701-707
Author(s):  
Hao Chen ◽  
Nobuyuki Horita ◽  
Hiromi Matsumoto ◽  
Ho Namkoong ◽  
Yu Hara ◽  
...  
Keyword(s):  
Risk Factor ◽  
Blood Group ◽  
Meta Analysis ◽  
Abo Blood Group

ABO Blood Group Is a Predictor for the Development of Venous Thromboembolism After Total Joint Arthroplasty

2017 ◽  
Vol 32 (9) ◽  
pp. S254-S258 ◽  
Author(s):  
Jared M. Newman ◽  
Matthew V. Abola ◽  
Alexandra Macpherson ◽  
Alison K. Klika ◽  
Wael K. Barsoum ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Blood Group ◽  
Total Joint Arthroplasty ◽  
Joint Arthroplasty ◽  
Abo Blood Group
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