scholarly journals Data Science Approaches for Effective Use of Mobile Device–Based Collection of Real‐World Data

2020 ◽  
Vol 107 (4) ◽  
pp. 719-721 ◽  
Author(s):  
Larsson Omberg ◽  
Elias Chaibub Neto ◽  
Lara M. Mangravite
Keyword(s):  
Mobile Device ◽  
Real World ◽  
Data Science ◽  
Real World Data ◽  
World Data ◽  
Effective Use

scholarly journals DFT21: Discrete Fourier Transform in the 21st century

2021 ◽  
Author(s):  
Prasanta Pal ◽  
Shataneek Banerjee ◽  
Amardip Ghosh ◽  
David R. Vago ◽  
Judson Brewer
Keyword(s):  
Time Series ◽  
Fourier Transform ◽  
Frequency Domain ◽  
Discrete Fourier Transform ◽  
Real World ◽  
Data Science ◽  
Digital Data ◽  
Series Data ◽  
Real World Data ◽  
World Data

<div> <div> <div> <p>Knowingly or unknowingly, digital-data is an integral part of our day-to-day lives. Realistically, there is probably not a single day when we do not encounter some form of digital-data. Typically, data originates from diverse sources in various formats out of which time-series is a special kind of data that captures the information about the time-evolution of a system under observation. How- ever, capturing the temporal-information in the context of data-analysis is a highly non-trivial challenge. Discrete Fourier-Transform is one of the most widely used methods that capture the very essence of time-series data. While this nearly 200-year-old mathematical transform, survived the test of time, however, the nature of real-world data sources violates some of the intrinsic properties presumed to be present to be able to be processed by DFT. Adhoc noise and outliers fundamentally alter the true signature of the frequency domain behavior of the signal of interest and as a result, the frequency-domain representation gets corrupted as well. We demonstrate that the application of traditional digital filters as is, may not often reveal an accurate description of the pristine time-series characteristics of the system under study. In this work, we analyze the issues of DFT with real-world data as well as propose a method to address it by taking advantage of insights from modern data-science techniques and particularly our previous work SOCKS. Our results reveal that a dramatic, never-before-seen improvement is possible by re-imagining DFT in the context of real-world data with appropriate curation protocols. We argue that our proposed transformation DFT21 would revolutionize the digital world in terms of accuracy, reliability, and information retrievability from raw-data. </p> </div> </div> </div>

scholarly journals DFT21: Discrete Fourier Transform in the 21st century

2021 ◽  
Author(s):  
Prasanta Pal ◽  
Shataneek Banerjee ◽  
Amardip Ghosh ◽  
David R. Vago ◽  
Judson Brewer
Keyword(s):  
Time Series ◽  
Fourier Transform ◽  
Frequency Domain ◽  
Discrete Fourier Transform ◽  
Real World ◽  
Data Science ◽  
Digital Data ◽  
Series Data ◽  
Real World Data ◽  
World Data

<div> <div> <div> <p>Knowingly or unknowingly, digital-data is an integral part of our day-to-day lives. Realistically, there is probably not a single day when we do not encounter some form of digital-data. Typically, data originates from diverse sources in various formats out of which time-series is a special kind of data that captures the information about the time-evolution of a system under observation. How- ever, capturing the temporal-information in the context of data-analysis is a highly non-trivial challenge. Discrete Fourier-Transform is one of the most widely used methods that capture the very essence of time-series data. While this nearly 200-year-old mathematical transform, survived the test of time, however, the nature of real-world data sources violates some of the intrinsic properties presumed to be present to be able to be processed by DFT. Adhoc noise and outliers fundamentally alter the true signature of the frequency domain behavior of the signal of interest and as a result, the frequency-domain representation gets corrupted as well. We demonstrate that the application of traditional digital filters as is, may not often reveal an accurate description of the pristine time-series characteristics of the system under study. In this work, we analyze the issues of DFT with real-world data as well as propose a method to address it by taking advantage of insights from modern data-science techniques and particularly our previous work SOCKS. Our results reveal that a dramatic, never-before-seen improvement is possible by re-imagining DFT in the context of real-world data with appropriate curation protocols. We argue that our proposed transformation DFT21 would revolutionize the digital world in terms of accuracy, reliability, and information retrievability from raw-data. </p> </div> </div> </div>

scholarly journals A Study of Real World Data Visualization of COVID-19 dataset using Python

2020 ◽  
Vol 4 (8) ◽  
pp. 104-107
Keyword(s):  
Machine Learning ◽  
Data Visualization ◽  
Real World ◽  
Data Science ◽  
Real World Data ◽  
World Data ◽  
Corona Virus ◽  
To Come

The importance of data science and machine learning is evident in all the domains where any kind of data is generated. The multi aspect analysis and visualizations help the society to come up with useful solutions and formulate policies. This paper takes the live data of current pandemic of Corona Virus and presents multi-faceted views of the data as to help the authorities and Governments to take appropriate decisions to takle this unprecedented problem. Python and its libraries along with Google Colab platform is used to get the results. The best possible techniques and combinations of modules/libraries are used to present the information related to COVID-19..

scholarly journals Time to really share real-world data?

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1054 ◽  
Author(s):  
Sophie Graham ◽  
Laura McDonald ◽  
Radek Wasiak ◽  
Michael Lees ◽  
Sreeram Ramagopalan
Keyword(s):  
Clinical Trials ◽  
Real World ◽  
Open Science ◽  
Healthcare Decision ◽  
High Likelihood ◽  
Real World Data ◽  
World Data ◽  
Healthcare Decision Making ◽  
Effective Use ◽  
Opening Up

Data other than that from clinical trials are important for healthcare decision making. However, unlike the vocal calls seen for more open access to trial data, there are limited efforts being made to ensure that agencies that collect real-world data (RWD) share this, despite its importance. There are many RWD sources across the world that could be readily exploited for research once shared. There are policy and privacy questions that need to be tackled, but opening up and sharing RWD offers remarkable potential for improvements in care for individuals and more effective use of limited healthcare resources. Open science should become the standard for RWD as well as clinical trials, especially those that have a high likelihood to influence practice.

scholarly journals Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care

2018 ◽  
Vol 11 (5) ◽  
pp. 450-460 ◽  
Author(s):  
Brandon Swift ◽  
Lokesh Jain ◽  
Craig White ◽  
Vasu Chandrasekaran ◽  
Aman Bhandari ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Patient Care ◽  
Real World ◽  
Data Science ◽  
Real World Data ◽  
World Data

scholarly journals Education for Real-World Data Science Roles (Part 2): A Translational Approach to Curriculum Development

2017 ◽  
Vol 11 (2) ◽  
pp. 13-26 ◽  
Author(s):  
Liz Lyon ◽  
Eleanor Mattern
Keyword(s):  
Real World ◽  
Data Science ◽  
Information Science ◽  
Small Scale ◽  
Stepping Stones ◽  
Real World Data ◽  
World Data ◽  
Curriculum Review ◽  
Data Analyst ◽  
Translational Approach

This study reports on the findings from Part 2 of a small-scale analysis of requirements for real-world data science positions and examines three further data science roles: data analyst, data engineer and data journalist. The study examines recent job descriptions and maps their requirements to the current curriculum within the graduate MLIS and Information Science and Technology Masters Programs in the School of Information Sciences (iSchool) at the University of Pittsburgh. From this mapping exercise, model ‘course pathways’ and module ‘stepping stones’ have been identified, as well as course topic gaps and opportunities for collaboration with other Schools. Competency in four specific tools or technologies was required by all three roles (Microsoft Excel, R, Python and SQL), as well as collaborative skills (with both teams of colleagues and with clients). The ability to connect the educational curriculum with real-world positions is viewed as further validation of the translational approach being developed as a foundational principle of the current MLIS curriculum review process 

The Use of CDISC Standards for Real-World Data (RWD): Expert Perspectives from a Qualitative Delphi Survey (Preprint)

2021 ◽  
Author(s):  
Rhonda Facile ◽  
Erin Elizabeth Muhlbradt ◽  
Mengchun Gong ◽  
Qing-Na Li ◽  
Vaishali B. Popat ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Clinical Research ◽  
Real World ◽  
Data Science ◽  
Health Data ◽  
Delphi Survey ◽  
Data Standards ◽  
Real World Data ◽  
World Data

BACKGROUND Real World Data (RWD) and Real World Evidence (RWE) have an increasingly important role in clinical research and health care decision making in many countries. In order to leverage RWD and generate reliable RWE, a framework must be in place to ensure that the data is well-defined and structured in a way that is semantically interoperable and consistent across stakeholders. The adoption of data standards is one of the cornerstones supporting high-quality evidence for clinical medicine and therapeutics development. CDISC data standards are mature, globally recognized and heavily utilized by the pharmaceutical industry for regulatory submission in the US and Japan and are recommended in Europe and China. Against this backdrop, the CDISC RWD Connect Initiative was initiated to better understand the barriers to implementing CDISC standards for RWD and to identify the tools and guidance needed to more easily implement CDISC standards for this purpose. We believe that bridging the gap between RWD and clinical trial generated data will benefit all stakeholders. OBJECTIVE The aim of this project was to understand the barriers to implementing CDISC standards for Real World Data (RWD) and to identify what tools and guidance may be needed to more easily implement CDISC standards for this purpose. METHODS We conducted a qualitative Delphi survey involving an Expert Advisory Board (EAB) with multiple key stakeholders, with three rounds of input and review. RESULTS In total, 66 experts participated in round 1, 56 participated in round 2 and 49 participated in round 3 of the Delphi Survey. Their input was collected and analyzed culminating in group statements. It was widely agreed that the standardization of RWD is highly necessary, and the primary focus should be on its ability to improve data-sharing and the quality of RWE. The priorities for RWD standardization include electronic health records, such as data shared using HL7 FHIR, and data stemming from observational studies. With different standardization efforts already underway in these areas, a gap analysis should be performed to identify areas where synergies and efficiencies are possible and then collaborate with stakeholders to create, or extend existing, mappings between CDISC and other standards, controlled terminologies and models to represent data originating across different sources. CONCLUSIONS There are many ongoing data standardization efforts that span the spectrum of human health data related activities including, but not limited to, those related to healthcare, public health, product or disease registries and clinical research, each with different definitions, levels of granularity and purpose. Amongst these standardization efforts, CDISC has been successful in standardizing clinical trial-based data for regulation worldwide. However, the complexity of the CDISC standards, and the fact that they were developed for different purposes, combined with the lack of awareness and incentives to using a new standard, insufficient training and implementation support are significant barriers for setting up the use of CDISC standards for RWD. The collection and dissemination of use cases showing in detail how to effectively implement CDISC standards for RWD, developing tools and support systems specifically for the RWD community, and collaboration with other standards development organizations and initiatives are potential steps towards connecting RWD to research. The integrity of RWE is dependent on the quality of the RWD and the data standards utilized in its collection, integration, processing, exchange and reporting. Using CDISC as part of the database schema will help to link clinical trial data and RWD and promote innovation in health data science. The authors believe that CDISC standards, if adapted carefully and presented appropriately to the RWD community, can provide “FAIR” structure and semantics for common clinical concepts and domains and help to bridge the gap between RWD and clinical trial generated data. CLINICALTRIAL Not Applicable

Abstract #946: Assessment of Acromegaly Patients with and Without Diabetes Treated with Lanreotide Depot: 2-Year Real World Data

2016 ◽  
Vol 22 ◽  
pp. 219
Author(s):  
Roberto Salvatori ◽  
Olga Gambetti ◽  
Whitney Woodmansee ◽  
David Cox ◽  
Beloo Mirakhur ◽  
...  
Keyword(s):  
Real World ◽  
Real World Data ◽  
World Data
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