scholarly journals Changes in glucagon‐like peptide 1 and 2 levels in people with obesity after a diet‐induced weight‐loss intervention are related to a specific microbiota signature: A prospective cohort study

2021 ◽  
Vol 11 (11) ◽  
Author(s):  
M‐Mar Rodríguez‐Peña ◽  
Brenno Astiarraga ◽  
Jesus Seco ◽  
Victoria Ceperuelo‐Mallafré ◽  
Adrià Caballé ◽  
...  







2019 ◽  
Vol 15 (2) ◽  
pp. 161-167 ◽  
Author(s):  
Tone Nygaard Flølo ◽  
Grethe S. Tell ◽  
Ronette L. Kolotkin ◽  
Anny Aasprang ◽  
Tone M. Norekvål ◽  
...  


2016 ◽  
Vol 68 (5) ◽  
pp. 743-749 ◽  
Author(s):  
Seth F. Helfenstein ◽  
Alexandra Uster ◽  
Maya Rühlin ◽  
Miklos Pless ◽  
Peter E. Ballmer ◽  
...  


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Martin Aasbrenn ◽  
Stian Lydersen ◽  
Per G. Farup

Background. Irritable bowel syndrome (IBS) is common in subjects with morbid obesity; the effect of weight loss programs on bowel symptoms is largely unknown. Methods. This prospective cohort study explored bowel symptoms, health scores, and biomarkers in subjects with morbid obesity during a six-month-long conservative weight loss intervention. Bowel symptoms were assessed with IBS-severity scoring system (IBS-SSS) and Gastrointestinal Symptom Rating Scale-IBS. Changes in all variables and associations between the changes in bowel symptoms and the other variables were analysed. Results. Eighty-eight subjects (81% females) were included. Body mass index was reduced from 42.0 (3.6) to 38.7 (3.5) (p<0.001). IBS-SSS was reduced from 116 (104) to 81 (84) (p=0.001). In all, 19 out of 25 variables improved significantly. In subjects with and without IBS at inclusion, the improvement in IBS-SSS was 88 (95% CI 55 to 121) and 10 (95% CI −9 to 29), respectively. Improved bowel symptoms were associated with improved subjective well-being, sense of humour, and vitamin D and negatively associated with reduced body mass index. Conclusion. Body mass index and health scores improved during a conservative weight loss intervention. Subjects with IBS before the intervention had a clinically significant improvement in bowel symptoms.





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