scholarly journals Comparative analysis of global transcriptome, proteome and acetylome in house dust mite‐induced murine allergic asthma model

2021 ◽  
Vol 11 (11) ◽  
Author(s):  
Yahui Liu ◽  
Qianru Huang ◽  
Juan Du ◽  
Chunrong Huang ◽  
Dan Li ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Allergic Asthma ◽  
House Dust ◽  
House Dust Mite ◽  
Asthma Model ◽  
Dust Mite ◽  
Global Transcriptome

Prime role of IL-17A in neutrophilia and airway smooth muscle contraction in a house dust mite–induced allergic asthma model

2015 ◽  
Vol 135 (6) ◽  
pp. 1643-1645.e5 ◽  
Author(s):  
Julie Chesné ◽  
Faouzi Braza ◽  
Gilliane Chadeuf ◽  
Guillaume Mahay ◽  
Marie-Aude Cheminant ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Muscle Contraction ◽  
Allergic Asthma ◽  
Airway Smooth Muscle ◽  
House Dust ◽  
House Dust Mite ◽  
Smooth Muscle Contraction ◽  
Asthma Model ◽  
Dust Mite

scholarly journals Lung miRNA profiles show a time‐of‐day response in house dust mite‐induced allergic asthma in mice

2021 ◽  
Vol 11 (6) ◽  
Author(s):  
Isaac Kirubakaran Sundar ◽  
Ashokkumar Srinivasan
Keyword(s):  
Allergic Asthma ◽  
House Dust ◽  
House Dust Mite ◽  
Time Of Day ◽  
Dust Mite

scholarly journals Effects of sublingual immunotherapy in a murine asthma model sensitized by intranasal administration of house dust mite extracts

2017 ◽  
Vol 66 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Kenjiro Shima ◽  
Toshiyuki Koya ◽  
Keisuke Tsukioka ◽  
Takuro Sakagami ◽  
Takashi Hasegawa ◽  
...  
Keyword(s):  
House Dust ◽  
House Dust Mite ◽  
Intranasal Administration ◽  
Sublingual Immunotherapy ◽  
Asthma Model ◽  
Dust Mite ◽  
Murine Asthma Model

scholarly journals Oral immunotherapy with the ingestion of house dust mite extract in a murine model of allergic asthma

2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Yao-Tung Wang ◽  
Hsu-Chung Liu ◽  
Hui-Chen Chen ◽  
Yen-Ching Lee ◽  
Tung-Chou Tsai ◽  
...  
Keyword(s):  
Allergic Asthma ◽  
House Dust ◽  
House Dust Mite ◽  
Murine Model ◽  
Oral Immunotherapy ◽  
Mite Extract ◽  
Dust Mite ◽  
House Dust Mite Extract

scholarly journals Association between serum zonulin level and severity of house dust mite allergic asthma

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Shereen A. Baioumy ◽  
Aya Elgendy ◽  
Shereen M. Ibrahim ◽  
Sara I. Taha ◽  
Shaimaa H. Fouad
Keyword(s):  
Allergic Asthma ◽  
Intestinal Permeability ◽  
House Dust ◽  
House Dust Mite ◽  
Control Group ◽  
Asthmatic Patients ◽  
Mite Allergy ◽  
Significant Difference ◽  
Dust Mite ◽  
Barrier Defect

Abstract Background Increased intestinal permeability, either due to the exposure to antigens in asthmatic patients or due to a barrier defect, plays a critical role in susceptibility to environmental allergens. House dust mite allergy occurs more commonly than any other type of allergy among Egyptian asthmatic patients. Aim To assess the relation between serum zonulin level as a marker of increased intestinal permeability and the severity of house dust mite allergic asthma. Methods A case–control study which included 48 patients with house dust mite allergic asthma and 48 healthy control subjects attending the Allergy and Immunology Unit, Microbiology and Immunology Department, Faculty of Medicine, Zagazig University. Results A statistically significant difference was detected between the two studied groups with respect to serum IgE and serum zonulin levels (p ˂ 0.001 and ˂ 0.001, respectively). The mean serum zonulin was equal to 258.3 ± 153.01 ng/ml in the asthmatic group and 80 ± 13 ng/ml in the control group. Serum zonulin level significantly increased with the increase of asthma severity (p ˂ 0.001). The cut off value of serum zonulin was ≥ 198 ng/ml, and the area under the curve was 0.76. It displayed sensitivity equal to 80% and specificity equal to 71.4%. Its negative predictive value was equal to 83.3%. Conclusion Intestinal barrier dysfunction contributes to the pathogenesis of allergic asthma. Serum zonulin level reflects an increase in intestinal permeability. Zonulin acts as prognostic factor of severity in asthma. Correction of the gut barrier defect may have a potential positive prognostic effect in asthma.

Comparative analysis of the frequency of house dust mite specific and nonspecific Th1 and Th2 cells in skin lesions and peripheral blood of patients with atopic dermatitis

1996 ◽  
Vol 74 (7) ◽  
pp. 401-406 ◽  
Author(s):  
C. Neumann ◽  
C. Gutgesell ◽  
F. Fliegert ◽  
R. Bonifer ◽  
F. Herrmann
Keyword(s):  
Atopic Dermatitis ◽  
Comparative Analysis ◽  
House Dust ◽  
House Dust Mite ◽  
Peripheral Blood ◽  
Skin Lesions ◽  
Th2 Cells ◽  
Dust Mite ◽  
Th1 And Th2

scholarly journals SQ house dust mite sublingually administered immunotherapy tablet (ALK) improves allergic rhinitis in patients with house dust mite allergic asthma and rhinitis symptoms

2015 ◽  
Vol 114 (2) ◽  
pp. 134-140.e1 ◽  
Author(s):  
Holger Mosbech ◽  
G. Walter Canonica ◽  
Vibeke Backer ◽  
Frederic de Blay ◽  
Ludger Klimek ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Allergic Asthma ◽  
House Dust ◽  
House Dust Mite ◽  
Dust Mite

scholarly journals Prophylactic benefits of systemically delivered simvastatin treatment in a house dust mite challenged murine model of allergic asthma

2018 ◽  
Vol 175 (7) ◽  
pp. 1004-1016 ◽  
Author(s):  
Aruni Jha ◽  
Min H Ryu ◽  
Ojo OO ◽  
Hilary J Bews ◽  
Jules C Carlson ◽  
...  
Keyword(s):  
Allergic Asthma ◽  
House Dust ◽  
House Dust Mite ◽  
Murine Model ◽  
Simvastatin Treatment ◽  
Dust Mite

scholarly journals Semaphorin 3E Inhibits House Dust Mite–Induced Angiogenesis in a Mouse Model of Allergic Asthma

2019 ◽  
Vol 189 (4) ◽  
pp. 762-772 ◽  
Author(s):  
Nazanin Tatari ◽  
Hesam Movassagh ◽  
Lianyu Shan ◽  
Latifa Koussih ◽  
Abdelilah S. Gounni
Keyword(s):  
Mouse Model ◽  
Allergic Asthma ◽  
House Dust ◽  
House Dust Mite ◽  
Dust Mite
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