scholarly journals The relationship of semantic intrusions to different etiological subtypes of MCI and cognitively healthy older adults

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Marcela Kitaigorodsky ◽  
Elizabeth Crocco ◽  
Rosie E. Curiel‐Cid ◽  
Giselle Leal ◽  
Diane Zheng ◽  
...  
Keyword(s):  
Older Adults ◽  
Healthy Older Adults ◽  
Relationship Of ◽  
The Relationship

scholarly journals The Relationship of Aspiration Status With Tongue and Handgrip Strength in Healthy Older Adults

2011 ◽  
Vol 66A (4) ◽  
pp. 452-458 ◽  
Author(s):  
S. G. Butler ◽  
A. Stuart ◽  
X. Leng ◽  
E. Wilhelm ◽  
C. Rees ◽  
...  
Keyword(s):  
Older Adults ◽  
Handgrip Strength ◽  
Healthy Older Adults ◽  
Relationship Of ◽  
The Relationship

scholarly journals Normative Data for a Tablet-Based Dual-Task Assessment in Healthy Older Adults

2020 ◽  
Author(s):  
Maxime Lussier ◽  
Kathia Saillant ◽  
Tudor Vrinceanu ◽  
Carol Hudon ◽  
Louis Bherer
Keyword(s):  
Older Adults ◽  
Dual Task ◽  
Normative Data ◽  
Healthy Older Adults ◽  
Highly Educated ◽  
Coefficient Of Variability ◽  
French And English ◽  
Task Assessment ◽  
English Speaking ◽  
The Relationship

Abstract Objective The objective of this study is to provide normative data for a tablet-based dual-task assessment in older adults without cognitive deficits. Method In total, 264 participants aged between 60 and 90 years, French and English-speaking, were asked to perform two discrimination tasks, alone and concurrently. The participants had to answer as fast as possible to one or two images appearing in the center of the tablet by pressing to the corresponding buttons. Normative data are provided for reaction time (RT), coefficient of variation, and accuracy. Analyses of variance were performed by trial types (single-pure, single-mixed, dual-mixed), and linear regressions assessed the relationship between performance and sociodemographic characteristics. Results The participants were highly educated and a large proportion of them were women (73.9%). The accuracy on the task was very high across all blocks. RT data revealed both a task-set cost and a dual-task cost between the blocks. Age was associated with slower RT and with higher coefficient of variability. Men were significantly slower on dual-mixed trials, but their coefficient of variability was lower on single-pure trials. Education was not associated with performance. Conclusions This study provides normative data for a tablet-based dual-task assessment in older adults without cognitive impairment, which was lacking. All participants completed the task with good accuracy in less than 15 minutes and thus, the task is transferable to clinical and research settings.

Respiratory Periodicity and Electroencephalogram Arousals During Sleep in Older Adults

2007 ◽  
Vol 8 (4) ◽  
pp. 249-260 ◽  
Author(s):  
Barbara Waag Carlson ◽  
Virginia J. Neelon ◽  
John R. Carlson ◽  
Marilyn Hartman ◽  
Sunil Dogra
Keyword(s):  
Older Adults ◽  
Exploratory Study ◽  
High Variability ◽  
Arterial Oxygenation ◽  
Type B ◽  
Breathing Patterns ◽  
The Mean ◽  
Relationship Of ◽  
The Relationship ◽  
Electroencephalogram Eeg

The aim of this exploratory study was to examine the relationship of electroencephalogram (EEG) arousals to breathing patterns and the relationship of both arousals and breathing patterns to arterial oxygenation during sleep in older adults. Five older adults were monitored using standard polysomnography. Records were divided into 5-min segments and breathing patterns identified based on the level of respiratory periodicity and the variability in the frequency of breathing cycles. Standard criteria were used to determine sleep states and occurrence of EEG arousals. High respiratory periodicity was seen in 23% of the segments, whereas 24% had low respiratory periodicity with minimal variability in the frequency of breathing (Type A low respiratory periodicity) and 53% had low respiratory periodicity with high variability in the frequency of breathing (Type B low respiratory periodicity). Nearly all (97%) segments with high respiratory periodicity had EEG arousals, whereas fewer segments (33%) with low respiratory periodicity had arousals, regardless of the stage of sleep. Desaturations occurred more often in segments with high respiratory periodicity, F (2,4) = 57.3, p < .001, but overall, the mean SaO2 of segments with high respiratory periodicity did not differ from levels seen in segments with low respiratory periodicity, F( 2,4) = 0.77, ns. Our findings suggest that high respiratory periodicity is a common feature of EEG arousals and, in older adults, may be important for maintaining oxygen levels during desaturations during sleep.

scholarly journals Sex moderations in the relationship between aortic stiffness, cognition, and cerebrovascular reactivity in healthy older adults

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257815
Author(s):  
Dalia Sabra ◽  
Brittany Intzandt ◽  
Laurence Desjardins-Crepeau ◽  
Antoine Langeard ◽  
Christopher J. Steele ◽  
...  
Keyword(s):  
Older Adults ◽  
Vascular Diseases ◽  
Aortic Pulse Wave Velocity ◽  
Cerebrovascular Reactivity ◽  
Neuropsychological Battery ◽  
Healthy Older Adults ◽  
Moderation Model ◽  
Continuous Arterial Spin Labeling ◽  
Cine Phase Contrast ◽  
The Relationship

It is well established that sex differences exist in the manifestation of vascular diseases. Arterial stiffness (AS) has been associated with changes in cerebrovascular reactivity (CVR) and cognitive decline in aging. Specifically, older adults with increased AS show a decline on executive function (EF) tasks. Interestingly, the relationship between AS and CVR is more complex, where some studies show decreased CVR with increased AS, and others demonstrate preserved CVR despite higher AS. Here, we investigated the possible role of sex on these hemodynamic relationships. Acquisitions were completed in 48 older adults. Pseudo-continuous arterial spin labeling (pCASL) data were collected during a hypercapnia challenge. Aortic pulse wave velocity (PWV) data was acquired using cine phase contrast velocity series. Cognitive function was assessed with a comprehensive neuropsychological battery, and a composite score for EF was calculated using four cognitive tests from the neuropsychological battery. A moderation model test revealed that sex moderated the relationship between PWV and CVR and PWV and EF, but not between CVR and EF. Together, our results indicate that the relationships between central stiffness, cerebral hemodynamics and cognition are in part mediated by sex.

The Relationship of Older Adults' Activities and Body Mass Index

2007 ◽  
Vol 20 (2) ◽  
pp. 217-234 ◽  
Author(s):  
Kristi Rahrig Jenkins ◽  
Nancy H. Fultz
Keyword(s):  
Older Adults ◽  
Body Mass Index ◽  
Body Mass ◽  
Relationship Of ◽  
The Relationship

INCREASED INTRAMUSCULAR ADIPOSE TISSUE IS RELATED TO INCREASED CAPILLARIZATION IN OLDER ADULTS

2020 ◽  
pp. 1-5
Author(s):  
O. Addison
Keyword(s):  
Older Adults ◽  
Body Mass Index ◽  
Adipose Tissue ◽  
Body Mass ◽  
Medical Center ◽  
Linear Regression Analysis ◽  
Positive Development ◽  
Intramuscular Adipose Tissue ◽  
Relationship Of ◽  
The Relationship

Background: High levels of intramuscular adipose tissue and low levels of capillarization are both predicative of low muscle and mobility function in older adults, however little is known about their relationship. Objectives: The purpose of this study was to examine the relationship of intramuscular adipose tissue and capillarization in older adults. Setting: An outpatient medical center. Participants: Forty-seven sedentary adults (age 59.9 ± 1.0 years, BMI 32.0 ± 0.7 kg/m2, VO2max 22.4 ± 0.7 ml/kg/min); Measurements: All participants underwent CT scans to determine intramuscular adipose tissue and muscle biopsies to determine capillarization in the mid-thigh. A step-wise hierarchical linear regression analysis was used to examine the contributions of age, sex, race, body mass index, 2-hour postprandial glucose, VO2max, and muscle capillarization, to the variability in intramuscular adipose tissue. Results: The predictors as a group accounted for 38.1% of the variance in intramuscular adipose tissue, with body mass index and capillarization each significantly contributing to the final model (P<0.001). The part correlation of body mass index with intramuscular adipose tissue was r = 0.47, and the part correlation of capillarization with intramuscular adipose tissue was r = 0.39, indicating that body mass index and capillarization explained 22.1%, and 15.2% of the variance in intramuscular adipose tissue. Conclusions: While increased muscle capillarization is typically thought of as a positive development, in some clinical conditions, such as tendinopathies, an increase in capillarization is part of the pathological process related to expansion of the extracellular matrix and fibrosis. This may also be an explanation for the surprising finding that high capillarization is related to high levels of intramuscular adipose tissue. Future studies are necessary to determine the relationship of changes in both capillarization and intramuscular adipose tissue after interventions, such as exercise.

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