Cross-sectional and longitudinal associations between insulin-like growth factor I and metabolic syndrome: a general population study in German adults

2013 ◽  
Vol 29 (6) ◽  
pp. 452-462 ◽  
Author(s):  
Nele Friedrich ◽  
Matthias Nauck ◽  
Sabine Schipf ◽  
Henry Völzke ◽  
Georg Brabant ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Growth Factor ◽  
General Population ◽  
Population Study ◽  
Insulin Like Growth Factor ◽  
Cross Sectional ◽  
General Population Study ◽  
Factor I ◽  
Longitudinal Associations ◽  
Growth Factor I

Association between Insulin-Like Growth Factor I and the Incidence of Metabolic Syndrome: Results from the Study of Health in Pomerania.

2010 ◽  
pp. P2-172-P2-172
Author(s):  
N Friedrich ◽  
M Nauck ◽  
S Schipf ◽  
H Volzke ◽  
G Brabant ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Growth Factor ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Growth Factor I

scholarly journals Relation between insulin-like growth factor-I concentrations, osteoarthritis, bone density, and fractures in the general population: the Chingford study.

1996 ◽  
Vol 55 (12) ◽  
pp. 870-874 ◽  
Author(s):  
M E Lloyd ◽  
D J Hart ◽  
D Nandra ◽  
T E McAlindon ◽  
M Wheeler ◽  
...  
Keyword(s):  
Growth Factor ◽  
Bone Density ◽  
General Population ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Growth Factor I

scholarly journals Role of Nutritional Status in the Regulation of Adrenarche1

1999 ◽  
Vol 84 (11) ◽  
pp. 3936-3944
Author(s):  
Thomas Remer ◽  
Friedrich Manz
Keyword(s):  
Growth Factor ◽  
Nutritional Status ◽  
Healthy Children ◽  
Insulin Like Growth Factor ◽  
Adrenal Androgen ◽  
Cross Sectional ◽  
Factor I ◽  
Growth Factor I ◽  
Excretion Rates

The factors regulating adrenarche are unknown. Recent in vitro studies have demonstrated that insulin and insulin-like growth factor I induce major adrenal steroidogenic enzyme genes and increase the production of adrenal androgens. Literature findings strongly suggest that changes in body mass index (BMI) reflect an integrated nonhormonal index of changes in serum levels and/or bioactivities of insulin and insulin-like growth factor I. We therefore longitudinally investigated individual changes in BMI and urinary 24-h excretion rates of dehydroepiandrosterone sulfate (DHEAS) in a prepuberty (PreC; n = 22, 11 boys and 11 girls) and a puberty (PubC; n = 20, 10 boys and 10 girls) cohort of healthy children. Twenty-four-hour urine samples were collected at yearly intervals during observation periods that lasted at least 4 yr (comprising ≥5 consecutive 24-h urine collections). For 4-yr intervals highly significant tracking coefficients (P < 0.001) of 0.73 (PreC) and 0.93 (PubC) were observed for DHEAS, emphasizing the importance of individual (and genetic) influences on adrenal androgen excretion. In both cohorts almost 3-fold higher median increases in urinary DHEAS excretion rates (P < 0.05) were observed during the 1-yr period of the individually highest rises in BMI compared with the 1-yr period of significantly lower rises in BMI (P < 0.01) in the same children after the factor age was controlled for. However, no consistently significant associations were found between urinary DHEAS output and BMI from simple cross-sectional correlations at defined age points. These findings provide the first in vivo evidence that a change in the nutritional status, measurable in the form of Δ-BMI (but not BMI alone), is an important physiological regulator of adrenarche regardless of individual adrenal androgen excretion level, age, and developmental stage.

scholarly journals A cross-sectional investigation of breast density and insulin-like growth factor I

2003 ◽  
Vol 107 (6) ◽  
pp. 991-996 ◽  
Author(s):  
Gertraud Maskarinec ◽  
Andrew E. Williams ◽  
Rudolph Kaaks
Keyword(s):  
Growth Factor ◽  
Breast Density ◽  
Insulin Like Growth Factor ◽  
Cross Sectional ◽  
Factor I ◽  
Growth Factor I

Somatomedins in Adolescence: A Cross-Sectional Study of the Effect of Puberty on Plasma Insulin-Like Growth Factor I and II Levels*

1983 ◽  
Vol 57 (2) ◽  
pp. 268-271 ◽  
Author(s):  
ALICE M. LUNA ◽  
DARRELL M. WILSON ◽  
CHARLES J. WIBBELSMAN ◽  
RICHARD C. BROWN ◽  
RAYMOND J. NAGASHIMA ◽  
...  
Keyword(s):  
Growth Factor ◽  
Plasma Insulin ◽  
Cross Sectional Study ◽  
Insulin Like Growth Factor ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factor I ◽  
Growth Factor I

scholarly journals Relationship between Sex Hormone-Binding Globulin (SHBG) and Insulin-Like Growth Factor-I (IGF-I) with Metabolic Syndrome

2017 ◽  
Vol 60 (5) ◽  
pp. 3-5
Author(s):  
Yehia Shaker ◽  
Weaam Gouda ◽  
Lamiaa Mageed ◽  
Esmat Wahba ◽  
Mie Afify ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Growth Factor ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Insulin Like Growth Factor ◽  
Hormone Binding ◽  
Factor I ◽  
Igf I ◽  
Growth Factor I

Dietary and lifestyle factors in relation to plasma insulin-like growth factor I in a general population sample

2003 ◽  
Vol 12 (3) ◽  
pp. 229-234 ◽  
Author(s):  
N Baibas ◽  
C Bamia ◽  
E Vassilopoulou ◽  
J Sdrolias ◽  
A Trichopoulou ◽  
...  
Keyword(s):  
Growth Factor ◽  
General Population ◽  
Plasma Insulin ◽  
Population Sample ◽  
Lifestyle Factors ◽  
Insulin Like Growth Factor ◽  
General Population Sample ◽  
Factor I ◽  
Growth Factor I

Association between Insulin-like growth factor-I and the incidence of metabolic syndrome: Results from the Study of Health in Pomerania

2010 ◽  
Vol 72 (08/09) ◽  
Author(s):  
N Friedrich ◽  
M Nauck ◽  
H Völzke ◽  
G Brabant ◽  
H Wallaschofski
Keyword(s):  
Metabolic Syndrome ◽  
Growth Factor ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Growth Factor I
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