scholarly journals Six‐year follow‐up study on the association between white blood cell count and fasting blood glucose level in Chinese adults: A community‐based health examination survey

2019 ◽  
Vol 35 (4) ◽  
pp. e3125 ◽  
Author(s):  
Xiu Zang ◽  
Xiangyu Meng ◽  
Yun Wang ◽  
Xiao Jin ◽  
Tingting Wu ◽  
...  
1986 ◽  
Vol 3 (1) ◽  
pp. 33-37 ◽  
Author(s):  
L.-O. Ohlson ◽  
K. Svärdsudd ◽  
L. Welin ◽  
H. Eriksson ◽  
L. Wilhelmsen ◽  
...  

2017 ◽  
Vol 10 (1) ◽  
pp. 29 ◽  
Author(s):  
Aarti Jagannathan ◽  
Praveen Angadi ◽  
Arun Thulasi ◽  
Vinod Kumar ◽  
K Umamaheshwar ◽  
...  

2021 ◽  
Author(s):  
Fei Teng ◽  
Peng Lai ◽  
Liying Wang ◽  
Xuekui Liu ◽  
Houfa Geng ◽  
...  

Abstract Objective The aim of this study was to identify the relationships between gamma−glutamyltransferase (GGT) and fasting blood glucose (FBG) during a 6-year follow-up of subjects, and to evaluate if GGT is an independent factor affecting FBG. Methods Total of 1369 individuals from health examination survey at the urban area of Xuzhou, central China, were followed up for 6 years. The patients were divided into four groups according to their baseline GGT levels (in quartiles). The one-way ANOVA method was used to compare the differences of variables with basic line. The relationship between GGT and FBG levels was examined using repeated measurements ANOVA. Results The grouping of baseline GGT levels influenced changes in blood glucose during 6-year follow-up. In GGT quartile subgroups, the annual mean increase of FBG level shows a positive relationship with baseline GGT level. And this trend was even more pronounced in the highest baseline GGT group. Time course, baseline FBG and GGT groups at different individuals, which together affected the change of FBG level during the follow-up. Considering that baseline FBG may affect subsequent FBG levels, repeated measures ANOVA was used to exclude the effect of this factor. Results showed that different baseline GGT groups were still significantly associated with increased FBG levels during follow-up. GGT is an independent factor affecting FBG level(p<0.001). Conclusions The annual mean increase of FBG level shows a positive relationship with baseline GGT level. Higher baseline GGT levels resulted in a faster annual mean increase in FBG. GGT could be used for early detection of impaired fasting glucose regulation (IFG) patients in clinical field.


2022 ◽  
Vol 127 ◽  
Author(s):  
Linn Moberg ◽  
Jerzy Leppert ◽  
Simon Liljeström ◽  
Mattias Rehn ◽  
Lena Kilander ◽  
...  

Background: There is substantial evidence that midlife hypertension is a risk factor for late life dementia. Our aim was to investigate if even high blood pressure at a single timepoint in midlife can predict an increased risk for all-cause dementia, Alzheimer’s disease (AD), or vascular dementia (VaD) later in life. Methods: The community-based study population comprised 30,102 dementia-free individuals from the Westmannia Cardiovascular Risk Factors Study. The participants were aged 40 or 50 years when the health examination took place in 1990–2000. Diagnose registers from both hospitals and primary healthcare centers were used to identify individuals who after inclusion to the study developed dementia. The association between midlife high blood pressure (defined as systolic blood pressure >140 and/or diastolic blood pressure >90 mmHg) at a single timepoint and dementia was adjusted for age, gender, body mass index (BMI), fasting blood glucose, education, smoking, and physical activity level. Multivariate binary cox regression analyses were used. Results: After a mean follow-up time of 24 years resulting in 662,244 person/years, 761 (2.5%) individuals had been diagnosed with dementia. Midlife high blood pressure at a single timepoint predicted all-cause dementia (hazard ratio [HR]: 1.22, 95% confidence interval [CI]: 1.02–1.45) and VaD (HR: 2.10, 95% CI: 1.47–3.00) but not AD (HR: 1.06, 95% CI: 0.81–1.38). Conclusion: This study suggests that even midlife high blood pressure at a single timepoint predicts all-cause dementia and more than doubles the risk for VaD later in life independently of established confounders. Even though there was no such association with AD, this strengthens the importance of midlife health examinations in order to identify individuals with hypertension and initiate treatment.


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