Elevated serum triglyceride levels at first prenatal visit is associated with the development of gestational diabetes mellitus

2021 ◽  
Author(s):  
Ming Hu ◽  
Xiaohan Gu ◽  
Yang Niu ◽  
Wenyi Lu ◽  
Cuihua Huang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Elevated Serum ◽  
Serum Triglyceride ◽  
Prenatal Visit

scholarly journals Association of Elevated Serum Ferritin Levels and the Risk of Gestational Diabetes Mellitus in Pregnant Women: The Camden Study

Diabetes Care ◽  
2006 ◽  
Vol 29 (5) ◽  
pp. 1077-1082 ◽  
Author(s):  
X. Chen ◽  
T. O. Scholl ◽  
T. P. Stein
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Serum Ferritin ◽  
Elevated Serum

scholarly journals Effect of gestational diabetes mellitus on lipid profile: A systematic review and meta-analysis

Open Medicine ◽  
2021 ◽  
Vol 17 (1) ◽  
pp. 70-86
Author(s):  
Fatemeh Alsadat Rahnemaei ◽  
Reza Pakzad ◽  
Azam Amirian ◽  
Iraj Pakzad ◽  
Fatemeh Abdi
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Lipid Profile ◽  
Meta Analysis ◽  
Low Density Lipoprotein ◽  
Elevated Serum ◽  
Density Lipoprotein ◽  
Low Density

Abstract Gestational diabetes mellitus (GDM) can have adverse effects on pregnancy. GDM is associated with changes in the lipid profile of pregnant women. Finding out the early ways to diagnose GDM can prevent the adverse outcomes. This meta-analysis study aimed to determine the effect of GDM on lipid profile. PubMed, ProQuest, Web of Science, Scopus, Science Direct, Google Scholar, and ClinicalTrial were systematically searched for published articles relating to GDM until 2021 according to PRISMA guidelines. Newcastle Ottawa scale was used to assess the quality of the studies. Thirty-three studies with a sample size of 23,792 met the criteria for entering the meta-analysis. Pooled standardized mean difference (SMD) for total cholesterol (TC) and triglyceride (TG) was 0.23 mg/dL (95% CI: 0.11–0.34) and 1.14 mg/dL (95% CI: 0.91–1.38), respectively. The mean of TC and TG in people with GDM was higher than that in normal pregnant women. A similar pattern was observed for the very low-density lipoprotein (VLDL) and TG/high-density lipoprotein (HDL) ratio, with pooled SMD of 0.99 mg (95% CI: 0.71–1.27) and 0.65 mg (95% CI: 0.36–0.94), respectively. Pooled SMD for HDL was −0.35 mg/dL (95% CI: −0.54 to −0.16), women with GDM had a mean HDL lower than normal pregnant women. Although pooled SMD was higher for low-density lipoprotein (LDL) in the GDM group, this difference was not significant (0.14 [95% CI: −0.04 to 0.32]). Of all the lipid profiles, the largest difference between the GDM and control groups was observed in TG (SMD: 1.14). Elevated serum TG had the strongest effect on GDM. Higher levels of TC, LDL, VLDL, and TG/HDL ratio, and lower level of HDL were exhibited in GDM group. So, these markers can be considered as a reliable marker in the diagnosis of GDM.

scholarly journals Evaluation of the Value of Fasting Plasma Glucose in the First Prenatal Visit to Diagnose Gestational Diabetes Mellitus in China

Diabetes Care ◽  
2012 ◽  
Vol 36 (3) ◽  
pp. 586-590 ◽  
Author(s):  
W.-w. Zhu ◽  
H.-x. Yang ◽  
Y.-m. Wei ◽  
J. Yan ◽  
Z.-l. Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Prenatal Visit ◽  
Fasting Plasma

scholarly journals Elevated serum squalene and cholesterol synthesis markers in pregnant obese women with gestational diabetes mellitus

2014 ◽  
Vol 55 (12) ◽  
pp. 2644-2654 ◽  
Author(s):  
Helena E. Miettinen ◽  
Kristiina Rönö ◽  
Saila Koivusalo ◽  
Beata Stach-Lempinen ◽  
Maritta Pöyhönen-Alho ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Cholesterol Synthesis ◽  
Elevated Serum ◽  
Obese Women

scholarly journals ОLD VERSUS NEW RUSSIAN CRITERIA FOR GESTATIONAL DIABETES

2013 ◽  
Vol 19 (4) ◽  
pp. 367-373
Author(s):  
P. V. Popova ◽  
A. V. Dronova ◽  
E. R. Sadikova ◽  
M. P. Parkkinen ◽  
M. V. Bolshakova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Blood Glucose ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Prenatal Visit ◽  
Iadpsg Criteria ◽  
New Criteria

Objective. To compare the incidence of gestational diabetes mellitus (GDM), risk factors of its development when using the old (WHO, 1999) and the new Russian criteria (2012) and to assess the correspondence between fasting glycaemia and 75-g oral glucose tolerance test (OGTT), under the new criteria.Design and methods. A total of 354 pregnant women were screened for gestational diabetes mellitus by OGTT between weeks 24 and 28 of gestation. Fasting blood glucose at irst prenatal visit was obtained from the medical records. GDM for therapy initiation was diagnosed according to WHO criteria. GDM was also retrospectively deined according to the new IADPSG-criteria (fasting plasma glucose >5,1 and < 7,0 mmol/l at the irst prenatal visit or by OGTT fasting glucose >5,1 and/or ? 10,0 mmol/l after 1 hour and/or ? 8,5 mmol/l after 2 hours at 24–32 gestation week). Results. GDM was detected in 25,1 % according to the old criteria and in 26,8 % women under the new criteria by OGTT. Fasting glucose at the irst prenatal visit between 5,1 mmol/l and 7,0 mmol/l (that is, GDM under the new criteria) was deined in 92 (28,1 %) of 327 women with known fasting blood glucose level. Only in 34 (37 %) of 92 women with fasting glycemia > 5,1 mmol/l at the irst prenatal visit the results of OGTT met the criteria for GDM (IADPSG) at 24–28 weeks gestation. Total incidence of GDM according to the new criteria (at the irst prenatal visit and after 24 weeks of pregnancy) was 43,4 %. Conclusions. Application of the new Russian criteria leads to a signiicant increase in the frequency of GDM, mainly due to the fasting glucose level at the irst prenatal visit. In women with GDM, diagnosed according to the IADPSG-criteria (but not WHO), such risk factors of GDM as heredity for diabetes mellitus and hypertension before pregnancy were more often identiied compared with women without GDM.

Evaluation of the value of plasma concentration of copeptin in the first prenatal visit to diagnose gestational diabetes mellitus

2017 ◽  
Vol 54 (12) ◽  
pp. 1123-1129 ◽  
Author(s):  
He-hong Ma ◽  
Shuang-yan Yang ◽  
Pei Wang ◽  
Jun-Feng Zhang
Keyword(s):  
Diabetes Mellitus ◽  
Plasma Concentration ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Prenatal Visit
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