Levels of adiponectin, C‐reactive protein and interleukin‐1 receptor antagonist are associated with insulin sensitivity: a population‐based study

2008 ◽  
Vol 24 (5) ◽  
pp. 378-383 ◽  
Author(s):  
J. Saltevo ◽  
M. Laakso ◽  
J. Jokelainen ◽  
S. Keinänen‐Kiukaanniemi ◽  
E. Kumpusalo ◽  
...  
2007 ◽  
Vol 2007 ◽  
pp. 1-8 ◽  
Author(s):  
Juha Saltevo ◽  
Mauno Vanhala ◽  
Hannu Kautiainen ◽  
Esko Kumpusalo ◽  
Markku Laakso

This Finnish population-based study, mean age 46 years, evaluates the association of high-sensitivity C-reactive protein (hs-CRP), interleukin-1 receptor antagonist (IL-1Ra), and adiponectin with the NCEP and IDF definitions of metabolic syndrome (MetS). Adiponectin levels were higher, hs-CRP and IL-1Ra levels lower in subjects without MetS compared to subjects with MetS. If MetS was present according to both IDF and NCEP criteria, BMI, waist, triglycerides, hs-CRP, and IL-1Ra were significantly higher compared to subjects who had MetS according to either only IDF or only NCEP criteria. The hs-CRP, IL-1Ra, and adiponectin linearly correlated with the number of the components of MetS according to both definitions. Decreased levels of adiponectin and increased levels of hs-CRP and IL-1Ra are tightly associated with the components of MetS. Individuals who had MetS according to both criteria had the most adverse changes in cardiovascular risk factors.


Cytokine ◽  
2000 ◽  
Vol 12 (3) ◽  
pp. 246-252 ◽  
Author(s):  
G. Hartmann ◽  
M. Tschöp ◽  
R. Fischer ◽  
C. Bidlingmaier ◽  
R. Riepl ◽  
...  

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