Emerging roles of neural stem cells in cerebral cortex development and evolution

2012 ◽  
Vol 72 (7) ◽  
pp. 955-971 ◽  
Author(s):  
Víctor Borrell ◽  
Isabel Reillo
Keyword(s):  
Stem Cells ◽  
Cerebral Cortex ◽  
Neural Stem Cells ◽  
Cerebral Cortex Development ◽  
Development And Evolution

Stem Cells: Neural Stem Cells in Cerebral Cortex Development

2013 ◽  
pp. 137-159 ◽  
Author(s):  
Felipe Mora-Bermúdez ◽  
Miguel Turrero García ◽  
Wieland B. Huttner
Keyword(s):  
Stem Cells ◽  
Cerebral Cortex ◽  
Neural Stem Cells ◽  
Cerebral Cortex Development

Neural Stem Cells in Cerebral Cortex Development

2015 ◽  
pp. 1-25 ◽  
Author(s):  
Felipe Mora-Bermúdez ◽  
Miguel Turrero García ◽  
Wieland B. Huttner
Keyword(s):  
Stem Cells ◽  
Cerebral Cortex ◽  
Neural Stem Cells ◽  
Cerebral Cortex Development

Neural Stem Cells in Cerebral Cortex Development

2016 ◽  
pp. 157-181 ◽  
Author(s):  
Felipe Mora-Bermúdez ◽  
Miguel Turrero García ◽  
Wieland B. Huttner
Keyword(s):  
Stem Cells ◽  
Cerebral Cortex ◽  
Neural Stem Cells ◽  
Cerebral Cortex Development

scholarly journals Insights into the Biology and Therapeutic Applications of Neural Stem Cells

2016 ◽  
Vol 2016 ◽  
pp. 1-18 ◽  
Author(s):  
Lachlan Harris ◽  
Oressia Zalucki ◽  
Michael Piper ◽  
Julian Ik-Tsen Heng
Keyword(s):  
Stem Cells ◽  
Cerebral Cortex ◽  
Brain Injury ◽  
Neural Stem Cells ◽  
Human Brain ◽  
Therapeutic Potential ◽  
Biological Significance ◽  
Adult Brain ◽  
Cognitive Capacity ◽  
Molecular Characteristics

The cerebral cortex is essential for our higher cognitive functions and emotional reasoning. Arguably, this brain structure is the distinguishing feature of our species, and yet our remarkable cognitive capacity has seemingly come at a cost to the regenerative capacity of the human brain. Indeed, the capacity for regeneration and neurogenesis of the brains of vertebrates has declined over the course of evolution, from fish to rodents to primates. Nevertheless, recent evidence supporting the existence of neural stem cells (NSCs) in the adult human brain raises new questions about the biological significance of adult neurogenesis in relation to ageing and the possibility that such endogenous sources of NSCs might provide therapeutic options for the treatment of brain injury and disease. Here, we highlight recent insights and perspectives on NSCs within both the developing and adult cerebral cortex. Our review of NSCs during development focuses upon the diversity and therapeutic potential of these cells for use in cellular transplantation and in the modeling of neurodevelopmental disorders. Finally, we describe the cellular and molecular characteristics of NSCs within the adult brain and strategies to harness the therapeutic potential of these cell populations in the treatment of brain injury and disease.

Neural Stem Cells and New Neurons in the Cerebral Cortex of Stroke-Prone Spontaneously Hypertensive Rats After Stroke

2009 ◽  
Vol 41 (1) ◽  
pp. 55-65 ◽  
Author(s):  
Tatsuki Itoh ◽  
Takao Satou ◽  
Kumiko Takemori ◽  
Shigeo Hashimoto ◽  
Hiroyuki Ito
Keyword(s):  
Stem Cells ◽  
Cerebral Cortex ◽  
Neural Stem Cells ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive
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