Increased resting‐state activity in the cerebellum with mothers having less adaptive sensory processing and trait anxiety

Background: Sensory processing sensitivity (SPS) is a biologically based temperament trait associated with enhanced awareness and responsivity to environmental and social stimuli. Individuals with high SPS are more affected by their environments, which may result in overarousal, cognitive depletion, and fatigue. Method: We examined individual differences in resting-state (rs) brain connectivity (using functional MRI) as a function of SPS among a group of adults (M age = 66.13 ± 11.44 years) immediately after they completed a social affective “empathy” task. SPS was measured with the Highly Sensitive Person (HSP) Scale and correlated with rs brain connectivity. Results: Results showed enhanced rs brain connectivity within the ventral attention, dorsal attention, and limbic networks as a function of greater SPS. Region of interest analyses showed increased rs brain connectivity between the hippocampus and the precuneus (implicated in episodic memory); while weaker connectivity was shown between the amygdala and the periaqueductal gray (important for anxiety), and the hippocampus and insula (implicated in habitual cognitive processing). Conclusions: The present study showed that SPS is associated with rs brain connectivity implicated in attentional control, consolidation of memory, physiological homeostasis, and deliberative cognition. These results support theories proposing “depth of processing” as a central feature of SPS and highlight the neural processes underlying this cardinal feature of the trait.

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Neuronal variability of Resting State activity in Eating Disorders: increase and decoupling in Ventral Attention Network and relation with clinical symptoms

European Psychiatry ◽

10.1016/j.eurpsy.2018.08.005 ◽

2019 ◽

Vol 55 ◽

pp. 10-17 ◽

Cited By ~ 6

Author(s):

Angela V. Spalatro ◽

Federico Amianto ◽

Zirui Huang ◽

Federico D’Agata ◽

Mauro Bergui ◽

...

Keyword(s):

Eating Disorders ◽

Resting State ◽

Clinical Symptoms ◽

Blood Oxygen Level Dependent ◽

Healthy Controls ◽

Resting State Functional Connectivity ◽

Blood Oxygen Level ◽

Attention Network ◽

State Activity ◽

New Perspective

AbstractBackground:Despite the great number of resting state functional connectivity studies on Eating Disorders (ED), no biomarkers could be detected yet. Therefore, we here focus on a different measure of resting state activity that is neuronal variability. The objective of this study was to investigate neuronal variability in the resting state of women with ED and to correlate possible differences with clinical and psychopathological indices.Methods:58 women respectively 25 with Anorexia Nervosa (AN), 16 with Bulimia Nervosa (BN) and 17 matched healthy controls (CN) were enrolled for the study. All participants were tested with a battery of psychometric tests and underwent a functional Magnetic Resonance Imaging (fMRI) resting state scanning. We investigated topographical patterns of variability measured by the Standard Deviation (SD) of the Blood-Oxygen-Level-Dependent (BOLD) signal (as a measure of neuronal variability) in the resting-state and their relationship to clinical and psychopathological indices.Results:Neuronal variability was increased in both anorectic and bulimic subjects specifically in the Ventral Attention Network (VAN) compared to healthy controls. No significant differences were found in the other networks. Significant correlations were found between neuronal variability of VAN and various clinical and psychopathological indices.Conclusions:We here show increased neuronal variability of VAN in ED patients. As the VAN is relevant for switching between endogenous and exogenous stimuli, our results showing increased neuronal variability suggest unstable balance between body attention and attention to external world. These results offer new perspective on the neurobiological basis of ED. Clinical and therapeutic implication will be discussed.

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Ipsilateral Alteration of Resting State Activity Suggests That Cortical Dysfunction Contributes to the Pathogenesis of Cluster Headache

Brain Topography ◽

10.1007/s10548-016-0535-x ◽

2016 ◽

Vol 30 (2) ◽

pp. 281-289 ◽

Cited By ~ 6

Author(s):

Péter Faragó ◽

Nikoletta Szabó ◽

Eszter Tóth ◽

Bernadett Tuka ◽

András Király ◽

...

Keyword(s):

Cluster Headache ◽

Resting State ◽

State Activity ◽

Cortical Dysfunction

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Deconfounding the Effects of Resting State Activity on Task Activation Detection in fMRI

Multimodal Brain Image Analysis - Lecture Notes in Computer Science ◽

10.1007/978-3-642-33530-3_5 ◽

2012 ◽

pp. 51-60

Author(s):

Burak Yoldemir ◽

Bernard Ng ◽

Rafeef Abugharbieh

Keyword(s):

Resting State ◽

State Activity ◽

Activation Detection ◽

Task Activation

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Resting-State Activity and Prephenomenal Unity

Unlocking the Brain ◽

10.1093/acprof:oso/9780199826995.003.0006 ◽

2013 ◽

pp. 122-145

Author(s):

Georg Northoff

Keyword(s):

Resting State ◽

State Activity

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Decreased Resting-State Activity in the Precuneus Is Associated With Depressive Episodes in Recurrent Depression

The Journal of Clinical Psychiatry ◽

10.4088/jcp.15m10022 ◽

2017 ◽

Vol 78 (04) ◽

pp. e372-e382 ◽

Cited By ~ 21

Author(s):

Chun-Hong Liu ◽

Xin Ma ◽

Zhen Yuan ◽

Lu-Ping Song ◽

Bing Jing ◽

...

Keyword(s):

Resting State ◽

Recurrent Depression ◽

State Activity ◽

Depressive Episodes

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Relationship between sensory processing patterns, trait anxiety, and health-related quality of life in multiple sclerosis

Journal of Health Psychology ◽

10.1177/1359105319901316 ◽

2020 ◽

pp. 135910531990131

Author(s):

Brocha Z Stern ◽

Lauren B Strober ◽

Yael Goverover

Keyword(s):

Quality Of Life ◽

Multiple Sclerosis ◽

Trait Anxiety ◽

Sensory Processing ◽

Indirect Effects ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Sensory Processing Patterns

Sensory processing patterns may predict health-related quality of life. This study examined this relationship in persons with multiple sclerosis considering trait anxiety as a potential mediator. Participants ( n = 94) completed the Adolescent/Adult Sensory Profile and other self-report measures at one time point. Sensory processing patterns were significantly associated with trait anxiety and health-related quality of life. Direct and indirect effects of sensory processing patterns were identified on physical health-related quality of life, and indirect effects were identified on mental health-related quality of life. Facilitating adaptive behavioral responses to sensory information may promote health-related quality of life in this population.

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