Hypoxia-inducible factor-1α/interleukin-1β signaling enhances hepatoma epithelial-mesenchymal transition through macrophages in a hypoxic-inflammatory microenvironment

Jingying Zhang; Qi Zhang; Yu Lou; Qihan Fu; Qi Chen; Tao Wei; Jiaqi Yang; Jinlong Tang; Jianxin Wang; Yiwen Chen; Xiaoyu Zhang; Jian Zhang; Xueli Bai; Tingbo Liang

doi:10.1002/hep.29681

Hypoxia-inducible factor-1α/interleukin-1β signaling enhances hepatoma epithelial-mesenchymal transition through macrophages in a hypoxic-inflammatory microenvironment

Hepatology ◽

10.1002/hep.29681 ◽

2018 ◽

Vol 67 (5) ◽

pp. 1872-1889 ◽

Cited By ~ 59

Author(s):

Jingying Zhang ◽

Qi Zhang ◽

Yu Lou ◽

Qihan Fu ◽

Qi Chen ◽

...

Keyword(s):

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Interleukin 1Β ◽

Mesenchymal Transition ◽

Inflammatory Microenvironment ◽

Hypoxia Inducible Factor 1Α

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Parthenolide suppresses hypoxia-inducible factor-1α signaling and hypoxia induced epithelial-mesenchymal transition in colorectal cancer

International Journal of Oncology ◽

10.3892/ijo.2017.4166 ◽

2017 ◽

Vol 51 (6) ◽

pp. 1809-1820 ◽

Cited By ~ 16

Author(s):

Se Lim Kim ◽

Young Ran Park ◽

Soo Teik Lee ◽

Sang-Wook Kim

Keyword(s):

Colorectal Cancer ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α

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Abstract B169: Hypoxia-inducible factor 1α (HIF-1α) correlates with epithelial-mesenchymal transition (EMT) and tumor growth in thyroid cancer cell lines.

10.1158/1535-7163.targ-13-b169 ◽

2013 ◽

Author(s):

YJ Yang ◽

HJ Na ◽

Ws Kim ◽

Jp Bong ◽

Sj Baek ◽

...

Keyword(s):

Thyroid Cancer ◽

Tumor Growth ◽

Cell Lines ◽

Cancer Cell ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Thyroid Cancer Cell ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α ◽

Thyroid Cancer Cell Lines

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Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1α and Epithelial–Mesenchymal Transition

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-16-1762 ◽

2017 ◽

Vol 23 (14) ◽

pp. 3896-3905 ◽

Cited By ~ 15

Author(s):

Ahmed Atef Ibrahim ◽

Christian Schmithals ◽

Erik Kowarz ◽

Verena Köberle ◽

Bianca Kakoschky ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α

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Curcumin inhibits hypoxia inducible factor-1α-induced epithelial-mesenchymal transition in HepG2 hepatocellular carcinoma cells

Molecular Medicine Reports ◽

10.3892/mmr.2014.2551 ◽

2014 ◽

Vol 10 (5) ◽

pp. 2505-2510 ◽

Cited By ~ 36

Author(s):

WANXING DUAN ◽

YUANHONG CHANG ◽

RONG LI ◽

QINHONG XU ◽

JIANJUN LEI ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α

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Role of Wnt/β-catenin signaling pathway in epithelial-mesenchymal transition of human prostate cancer induced by hypoxia-inducible factor-1α

International Journal of Urology ◽

10.1111/j.1442-2042.2007.01866.x ◽

2007 ◽

Vol 14 (11) ◽

pp. 1034-1039 ◽

Cited By ~ 118

Author(s):

Yong-Guang Jiang ◽

Yong Luo ◽

Da-lin He ◽

Xiang Li ◽

Lin-lin Zhang ◽

...

Keyword(s):

Prostate Cancer ◽

Signaling Pathway ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Human Prostate ◽

Human Prostate Cancer ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α

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Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

BMC Cancer ◽

10.1186/1471-2407-13-108 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 168

Author(s):

Lin Zhang ◽

Gang Huang ◽

Xiaowu Li ◽

Yujun Zhang ◽

Yan Jiang ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α

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Hypoxia Induces Epithelial-Mesenchymal Transition in Follicular Thyroid Cancer: Involvement of Regulation of Twist by Hypoxia Inducible Factor-1α

Yonsei Medical Journal ◽

10.3349/ymj.2015.56.6.1503 ◽

2015 ◽

Vol 56 (6) ◽

pp. 1503 ◽

Cited By ~ 19

Author(s):

Yeon Ju Yang ◽

Hwi Jung Na ◽

Michelle J. Suh ◽

Myung Jin Ban ◽

Hyung Kwon Byeon ◽

...

Keyword(s):

Thyroid Cancer ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Follicular Thyroid Cancer ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α

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Hypoxia causes down-regulation of Dicer in hepatocellular carcinoma, which is required for up-regulation of hypoxia inducible factor 1α and epithelial-mesenchymal transition

Zeitschrift für Gastroenterologie ◽

10.1055/s-0036-1597476 ◽

2016 ◽

Vol 54 (12) ◽

pp. 1343-1404

Author(s):

AA Ibrahim ◽

C Schmithals ◽

E Kowarz ◽

V Köberle ◽

B Kakoschky ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Down Regulation ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α

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Hypoxia-inducible factor 1α participates in hypoxia-induced epithelial-mesenchymal transition via response gene to complement 32

Experimental and Therapeutic Medicine ◽

10.3892/etm.2017.4665 ◽

2017 ◽

Vol 14 (2) ◽

pp. 1825-1831 ◽

Cited By ~ 6

Author(s):

Liang Zhu ◽

Qiu Zhao

Keyword(s):

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Response Gene ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α

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Oridonin inhibits hypoxia-induced epithelial–mesenchymal transition and cell migration by the hypoxia-inducible factor-1α/matrix metallopeptidase-9 signal pathway in gallbladder cancer

Anti-Cancer Drugs ◽

10.1097/cad.0000000000000797 ◽

2019 ◽

Vol 30 (9) ◽

pp. 925-932 ◽

Cited By ~ 1

Author(s):

Kunlun Chen ◽

Jianwen Ye ◽

Lei Qi ◽

Yuan Liao ◽

Renfeng Li ◽

...

Keyword(s):

Cell Migration ◽

Gallbladder Cancer ◽

Epithelial Mesenchymal Transition ◽

Hypoxia Inducible Factor ◽

Signal Pathway ◽

Mesenchymal Transition ◽

Hypoxia Inducible Factor 1Α ◽

Matrix Metallopeptidase ◽

Matrix Metallopeptidase 9

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