Prospective assessment of a nasopharyngeal carcinoma risk score in a population undergoing screening

Author(s):  
Geng‐Hang Chen ◽  
Zhiwei Liu ◽  
Ming‐Fang Ji ◽  
Ruth M. Pfeiffer ◽  
Qi‐Hong Huang ◽  
...  
BMC Cancer ◽  
2007 ◽  
Vol 7 (1) ◽  
Author(s):  
Jun-Fang He ◽  
Wei-Hua Jia ◽  
Qin Fan ◽  
Xin-Xi Zhou ◽  
Hai-De Qin ◽  
...  

2019 ◽  
Vol 8 (5) ◽  
pp. 2561-2571 ◽  
Author(s):  
Ting Hu ◽  
Chu‐Yang Lin ◽  
Shang‐Hang Xie ◽  
Geng‐Hang Chen ◽  
Yu‐Qiang Lu ◽  
...  

Author(s):  
Mei-Hsuan Lee ◽  
Yu-Han Huang ◽  
Anna E Coghill ◽  
Zhiwei Liu ◽  
Kelly J Yu ◽  
...  

Abstract Nasopharyngeal carcinoma (NPC) is caused by Epstein-Barr virus (EBV) and is more likely to occur in susceptible families. Whether genetic susceptibility operates through altered EBV control is incompletely understood. We used a NPC risk prediction model based on 14 EBV markers to compare risk score distribution in unaffected members from multiplex families with that in population-based controls. Despite the absence of NPC at the time of antibody measurement, we observed an upward shift in risk score among multiplex family members compared to the general population, consistent with the possibility that genetic factors affect NPC risk through alterations in EBV control.


2008 ◽  
Vol 12 (3) ◽  
pp. 345-349 ◽  
Author(s):  
Xiang-Ling Feng ◽  
Wen Zhou ◽  
Hong Li ◽  
Wei-Yi Fang ◽  
Yi-Bo Zhou ◽  
...  

BMC Cancer ◽  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Wei-Hua Jia ◽  
Xiang-Yu Luo ◽  
Bing-Jian Feng ◽  
Hong-Lian Ruan ◽  
Jin-Xin Bei ◽  
...  

2015 ◽  
Vol 14 (4) ◽  
pp. 18945-18957 ◽  
Author(s):  
Y.-F. Yu ◽  
Z.-G. Han ◽  
W.-B. Guo ◽  
G.-J. Zhang ◽  
J.-K. Yang ◽  
...  

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Sukri Rahman ◽  
Bestari Jaka Budiman ◽  
Histawara Subroto

Abstrak           Latar belakang: Karsinoma nasofaring adalah tumor ganas epitel nasofaring yang sampai saat ini penyebabnya belum diketahui, infeksi virus Epstein Barr dilaporkan sebagai faktor dominan terjadinya karsinoma nasofaring tetapi faktor non viral juga berperan untuk timbulnya keganasan nasofaring. Tujuan: Untuk mengetahui faktor non viral  yang dapat meningkatkan kejadian karsinoma nasofaring sehingga dapat mencegah dan menghindari faktor-faktor non viral tersebut. Tinjauan Pustaka: Karsinoma nasofaring merupakan tumor ganas epitel nasofaring yang penyebabnya berhubungan dengan faktor viral dan non viral diantaranya asap rokok, ikan asin, formaldehid, genetik, asap kayu bakar , debu kayu, infeksi kronik telinga hidung tenggorok, alkohol dan obat tradisional. Kesimpulan: Pembuktian secara klinis dan ilmiah terhadap faktor non viral sebagai penyebab timbulnya karsinoma nasofaring masih belum dapat dijelaskan secara pasti. Faktor non viral merupakan salah satu faktor risiko yang dapat meningkatkan angka kejadian timbulnya keganasan nasofaring Kata kunci: karsinoma nasofaring, faktor risiko, non viral AbstractBackground: Nasopharyngeal carcinoma is a malignant epithelial nasopharyngeal tumor that until now the cause still unknown, Epstein barr virus infection had reported as predominant occurance of nasopharyngeal carcinoma but non viral factors may also contribute to the onset of the incidence of nasopharyngeal malignancy. Purpose: To find non viral factors that may increase the incidence of nasopharyngel carcinoma in order to prevent and avoid non-viral factors Literature: Nasopharyngeal carcinoma is a malignant tumor that causes nasopharyngeal epithelium associated with viral and non-viral factors such as cigarette smoke, salt fish, formaldehyde, genetic, wood smoke ,wood dust, ear nose throat chronic infections, alcohol, and traditional medicine. Conclusion: Clinically and scientifically proving the non-viral factors as the cause of nasopharyngeal carcinoma can not be explained with certainty. Non-viral factors only as one risk factor that can increase the incidence of the onset of nasopharyngeal carcinoma. Keywords:  nasopharyngeal carcinoma, risk factor, non viral


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