Development of semicrystalline poly(vinyl alcohol) hydrogels for biomedical applications

Poly(vinyl alcohol) is a non-toxic, biosynthetic polymer and biocompatible polymer that has the ability to form hydrogels either via chemical or physical crosslinking. Whilst chemical crosslinking provides greater control on the properties of the resultant hydrogel, physically crosslinked hydrogels or blends with other biocompatible polymers are more suited for biomedical applications. In this paper we report a systematic study on the effect of varying concentrations of PVA, physical methods of crosslinking, and PVA-gelatin and PVA-PVP blends on the physical and mechanical properties of the hydrogels.

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Synthesis of hybrid polymer networks of irradiated chitosan/poly(vinyl alcohol) for biomedical applications

Radiation Physics and Chemistry ◽

10.1016/j.radphyschem.2013.09.009 ◽

2014 ◽

Vol 96 ◽

pp. 115-119 ◽

Cited By ~ 22

Author(s):

Atif Islam ◽

Tariq Yasin ◽

Ihtesham ur Rehman

Keyword(s):

Vinyl Alcohol ◽

Biomedical Applications ◽

Polymer Networks ◽

Poly Vinyl Alcohol ◽

Hybrid Polymer

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Biocompatibility of Nanostructured Chitosan/Poly(Vinyl Alcohol) Blends Chemically Crosslinked with Genipin for Biomedical Applications

Journal of Biomedical Nanotechnology ◽

10.1166/jbn.2010.1110 ◽

2010 ◽

Vol 6 (2) ◽

pp. 166-175 ◽

Cited By ~ 40

Author(s):

Viviane M. Bispo ◽

Alexandra A. P. Mansur ◽

Edel F. Barbosa-Stancioli ◽

Herman S. Mansur

Keyword(s):

Vinyl Alcohol ◽

Biomedical Applications ◽

Poly Vinyl Alcohol

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Anisotropic tough poly(vinyl alcohol)/graphene oxide nanocomposite hydrogels for potential biomedical applications

RSC Advances ◽

10.1039/c8ra00340h ◽

2018 ◽

Vol 8 (24) ◽

pp. 13284-13291 ◽

Cited By ~ 10

Author(s):

Qiaomei Luo ◽

Yangyang Shan ◽

Xia Zuo ◽

Jiaqi Liu

Keyword(s):

Mechanical Properties ◽

Graphene Oxide ◽

Vinyl Alcohol ◽

Biomedical Applications ◽

Poly Vinyl Alcohol ◽

Nanocomposite Hydrogel ◽

Nanocomposite Hydrogels

Tough PVA/GO nanocomposite hydrogel with well-developed anisotropic microstructure and excellent mechanical properties.

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CHAPTER 10. Biomedical Applications of Hydrogels: Poly(vinyl alcohol)-Based Hydrogels for Embolotherapy and Drug Delivery

Polymeric and Self Assembled Hydrogels - Monographs in Supramolecular Chemistry ◽

10.1039/9781849735629-00232 ◽

2012 ◽

pp. 232-252

Author(s):

Andy Lewis ◽

Clare Heaysman

Keyword(s):

Drug Delivery ◽

Vinyl Alcohol ◽

Biomedical Applications ◽

Poly Vinyl Alcohol

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Effect of ZnO Concentration on the Diameter of Electrospun Fibers from Poly(Vinyl Alcohol) Composited with ZnO Nanoparticles

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.759.81 ◽

2018 ◽

Vol 759 ◽

pp. 81-85

Author(s):

Tongsai Jamnongkan ◽

Supranee Kaewpirom ◽

Amnuay Wattanakornsiri ◽

Rattanaphol Mongkholrattanasit

Keyword(s):

Zinc Oxide ◽

Zno Nanoparticles ◽

Vinyl Alcohol ◽

Biomedical Applications ◽

Processing Parameters ◽

Poly Vinyl Alcohol ◽

Electrospun Fibers ◽

Zno Nanoparticle ◽

The World ◽

Potential Use

Recently, the composited nanofiber attraction has been growing from researchers across the world due to its exciting opportunities for use in biomedical applications. In this study, we fabricated electrospun fibers from poly (vinyl alcohol) (PVA) composited with Zinc Oxide (ZnO) nanoparticle for potential use in biomedical applications. From the experimental results, there was not any chemical bonding between the ZnO nanoparticles and the PVA molecules. The effect of concentration of ZnO nanoparticles in PVA solution on the diameter of electrospun fibers was found that the diameter of electrospun fibers increased with raising the concentration of suspended ZnO nanoparticles in solution. This is probably because the effect of nanoparticles on the diameter of electrospun fibers was through their effect on the viscosity of solution. In addition, we found that the diameter of electrospun fibers depended on the solution and processing parameters.

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