Controlled surface morphology and hydrophilicity of polycaprolactone toward selective differentiation of mesenchymal stem cells to neural like cells

2014 ◽  
Vol 103 (5) ◽  
pp. 1875-1881 ◽  
Author(s):  
Hoda Jahani ◽  
Farid Azizi Jalilian ◽  
Chia‐Yu Wu ◽  
Saeid Kaviani ◽  
Masoud Soleimani ◽  
...  
2019 ◽  
Vol 9 (6) ◽  
pp. 760-769
Author(s):  
Yichen Du ◽  
Xiaohua Shi ◽  
Xin Zhou ◽  
Yao Chen ◽  
Hailin Wang ◽  
...  

The aim of this study was to prepare an engraving silicone rubber (SR) material with good biocompatibility and functionality. SR with different POSS-COOH proportions was produced by mixing POSS-COOH nanoparticles in medical liquid silicone. The viability, adhesion and differentiation of MSCs on the surface of the modified materials were examined. Compared with virgin SR, the hydrophilic property of the composites was obviously increased and hardness was decreased; however, there was no obvious change in the surface morphology of the POSS-COOH/SR. The results of MTT showed that the viability of MSCs on POSS-COOH/SR was significantly suppressed (P < 0.05). Furthermore, POSS-COOH/SR was able to induce significant adipogenesis differentiation of MSCs. Our results demonstrated POSS-COOH/SR not only improves cell compatibility, it promotes the adipogenic differentiation of MSCs. It may be used as a new soft tissue-filling material in the field of plastic surgery.


2010 ◽  
Vol 30 (6) ◽  
pp. 455-455 ◽  
Author(s):  
Dongyan Shi ◽  
Dan Ma ◽  
Feiqing Dong ◽  
Chen Zong ◽  
Liyue Liu ◽  
...  

2004 ◽  
Vol 171 (4S) ◽  
pp. 373-373
Author(s):  
Trinity J. Bivalacqua ◽  
Mustafa F. Usta ◽  
Hunter C. Champion ◽  
Weiwen Deng ◽  
Philip J. Kadowitz ◽  
...  

2008 ◽  
Vol 68 (S 01) ◽  
Author(s):  
S Mohr ◽  
BC Portmann-Lanz ◽  
A Schoeberlein ◽  
R Sager ◽  
DV Surbek

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