Mechanical in vitro fatigue testing of implant materials and components using advanced characterization techniques

The toxicity of implant materials requires investigation prior to clinical use. We have developed a method where materials are directly applied to the chorioallantoic membrane (CAM) of 9-day-old chick embryos and toxicity is assessed using histological criteria. We evaluated the method using metal foils. The number and organisation of fibroblasts seemed to be the most useful criteria for assessing metal toxicity. Differences were greatest after 10 days of culture on the CAM. The method is sensitive enough to enable us to discriminate between the less toxic aluminium and titanium and the highly toxic cobalt, nickel and tungsten. The proposed method has advantages over in vitro techniques which provide an abnormal fluid environment and in which the more complex interactions that are possible between implant materials and tissue in vivo cannot be modelled.

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Advanced characterization techniques for nanoscale photoresist structure (Conference Presentation)

10.1117/12.2554632 ◽

2020 ◽

Author(s):

Miquel Salmeron

Keyword(s):

Advanced Characterization ◽

Characterization Techniques

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Alfred University Student Chapter Holds Seminar on Advanced Characterization Techniques

MRS Bulletin ◽

10.1557/s0883769400046522 ◽

1992 ◽

Vol 17 (10) ◽

pp. 68-68

Keyword(s):

Advanced Characterization ◽

University Student ◽

Characterization Techniques ◽

Student Chapter

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Cultivation of Periodontal Ligament Fibroblasts on Dental Implant Materials and Enzymatically Debrided Teeth

Journal of Dental Research ◽

10.1177/00220345740530061301 ◽

1974 ◽

Vol 53 (6) ◽

pp. 1368-1376 ◽

Cited By ~ 2

Author(s):

T.K. Huard ◽

L.F. Arnold ◽

P. Baram

Keyword(s):

Rhesus Monkey ◽

Methyl Methacrylate ◽

Dental Implant ◽

Electron Micrographs ◽

Periodontal Ligament ◽

Scanning Electron Micrographs ◽

Periodontal Ligament Fibroblasts ◽

Implant Materials ◽

Scanning Electron

Rhesus monkey periodontal ligament-derived fibroblasts were cultured on glass, Vitallium, poly(methyl methacrylate) and enzymatically debrided teeth. Scanning electron micrographs of these preparations and of the periodontal ligament surrounding normal and replanted teeth were compared. The fibroblasts cultured in vitro could organize on implant material and enzymatically debrided teeth to produce a network with fibers resembling those that are seen in the normal periodontal ligament.

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