scholarly journals Diagnostic value of macrophage inhibitory cytokine 1 as a novel prognostic biomarkers for early gastric cancer screening

2020 ◽  
Vol 35 (1) ◽  
Author(s):  
Xin Ge ◽  
Xiaolei Zhang ◽  
Yanling Ma ◽  
Shaohua Chen ◽  
Zhaowu Chen ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Screening ◽  
Early Gastric Cancer ◽  
Diagnostic Value ◽  
Prognostic Biomarkers ◽  
Gastric Cancer Screening

Hsa_circ_0065149 is an Indicator for Early Gastric Cancer Screening and Prognosis Prediction

2019 ◽  
Vol 26 (3) ◽  
pp. 1475-1482 ◽  
Author(s):  
Yongfu Shao ◽  
Xueping Tao ◽  
Rongdan Lu ◽  
Haiqiang Zhang ◽  
Jiaxin Ge ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Screening ◽  
Early Gastric Cancer ◽  
Prognosis Prediction ◽  
Gastric Cancer Screening

COMPARISON OF THE DIAGNOSTIC UTILITY OF THE ULTRATHIN ENDOSCOPE AND THE CONVENTIONAL ENDOSCOPE IN EARLY GASTRIC CANCER SCREENING

2009 ◽  
Vol 21 (2) ◽  
pp. 116-121 ◽  
Author(s):  
Yuko Hayashi ◽  
Yorimasa Yamamoto ◽  
Takanori Suganuma ◽  
Kazuhisa Okada ◽  
Masami Nego ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Screening ◽  
Early Gastric Cancer ◽  
Diagnostic Utility ◽  
Gastric Cancer Screening

Outcomes and efficiency of national gastric cancer screening program in Korea: Single-center, large-scale study.

2012 ◽  
Vol 30 (4_suppl) ◽  
pp. 29-29
Author(s):  
Beom Jin Kim ◽  
Chae Heo ◽  
Bong Ki Cha ◽  
Jae G. Kim ◽  
Sang-Jung Kim
Keyword(s):  
Gastric Cancer ◽  
Cancer Screening ◽  
Early Gastric Cancer ◽  
Large Scale ◽  
Screening Tool ◽  
Screening Program ◽  
University Hospital ◽  
Female Ratio ◽  
Cancer Screening Program ◽  
Gastric Cancer Screening

29 Background: Gastric cancer is a major cause of death and a substantial socioeconomic burden in Korea. The National Cancer Screening Program for Medicaid recipients was initiated in 1999 and has contributed to reduction of cancer-related mortality in Korea. Endoscopy may be cost-effective screening tool in Korea, where the cost of endoscopy and UGIS are similar and the incidence of gastric cancer is high. Most of Japanese studies on the efficiency of mass screening for gastric cancer have dealt with photoflurography as a screening tool. Although biennial gastric cancer screening by endoscopy has been increasing in Korea as part of the National Cancer Screening Program, few studies have evaluated its efficiency. Therefore, we analyzed the outcomes and efficiency of the National Gastric Cancer Screening Program using endoscopy in Korea. Methods: We reviewed medical records from the National Gastric Cancer Screening Program at Chung-Ang University hospital in Korea from January 2007 to December 2010. The study population was comprised of Medicaid recipients ≥ 40 years of age who were taken from the National Health Insurance Corporation. Results: A total of 41,150 asymptomatic subjects underwent endoscopy for gastric cancer screening. The mean age of the screened subjects was 56.3 years for men and 48.9 years for women. The male to female ratio of the screened subjects was 1.57:1. Gastric cancer was diagnosed in 102 (0.24%) of 41,150 subjects (60 men and 42 women). Their mean age was 54.4 years. Of these, 76 subjects (0.18%) were diagnosed as early gastric cancer and 26 subjects (0.06%) as advanced gastric cancer. The proportion of early gastric cancer among total gastric cancers was 74.5%. During the period, only 6,586 (16.0%) subjects participated in the biennial gastric cancer screening (59% for men and 49% for women). Conclusions: Despite accomplishments of the National Gastric Cancer Screening Program in Korea, low compliance to the screening program remains an issue. Furthermore, its cost-effectiveness analysis will be needed for successful progression.

scholarly journals Quality management system for screening esophagogastroduodenoscopy improves detection of Helicobacter pylori-negative interval gastric cancer

2021 ◽  
Vol 09 (12) ◽  
pp. E1900-E1908
Author(s):  
Fumiaki Ishibashi ◽  
Konomi Kobayashi ◽  
Tomohiro Kawakami ◽  
Ryu Tanaka ◽  
Kazuaki Sugihara ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cancer Screening ◽  
Quality Management ◽  
Early Gastric Cancer ◽  
Detection Rate ◽  
Quality Management System ◽  
Detection Rates ◽  
Cancer Group ◽  
Gastric Cancer Screening

Abstract Background and study aims Double-checking the findings of examinations is necessary for endoscopy quality control in gastric cancer screening; however, there have been no reports showing its effectiveness. We prospectively analyzed the effectiveness of a quality management system (QMS) in endoscopy for gastric cancer screening. Patients and methods QMS was defined as having images and reports checked by a second endoscopist on the same day and reporting inconsistencies to the examining endoscopist. Patients diagnosed with early gastric cancer (EGC) in the 2 years before and after the introduction of QMS were divided into two groups: the interval cancer group, which included those for whom cancer was detected within 1 year of the last endoscopy and the noninterval cancer group. Changes in detection rates were compared. Results Before the introduction of QMS, 11 interval EGC cases were diagnosed among 36,189 endoscopies, whereas after the introduction, 32 interval ECG cases were diagnosed among 38,290 endoscopies (P = 0.004). Fifteen noninterval EGC cases were diagnosed before the introduction, while 12 noninterval EGC cases were diagnosed after the introduction; no significant difference was observed. Subanalyses by Helicobacter pylori (HP) infection status revealed no difference in the detection rate among HP-positive EGC patients, but the detection rates among HP-eradicated and HP-naïve EGC patients were improved (P = 0.005 and P = 0.011). Logistic regression analysis showed that QMS was an independent predictor for detection of HP-negative interval EGC (P = 0.017, OR = 4.4, 95 % CI: 2.0–9.7). Conclusions QMS improved the detection rate for HP-negative interval early gastric cancer. (UMIN000042991)

Fluorescent paper-based analytical devices for ultra-sensitive dual-type RNA detections and accurate gastric cancer screening

2021 ◽  
pp. 113781
Author(s):  
Yuqian Liu ◽  
Ruyi Li ◽  
Fangyuan Liang ◽  
Chao Deng ◽  
Farzad Seidi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Screening ◽  
Gastric Cancer Screening

Gastric Cancer Screening in Japan

2018 ◽  
pp. 99-117
Author(s):  
Shigemi Nakajima
Keyword(s):  
Gastric Cancer ◽  
Cancer Screening ◽  
Gastric Cancer Screening

scholarly journals A case of initial H. pylori infection in an adult, found by blood test for gastric cancer screening

2017 ◽  
Vol 90 (1) ◽  
pp. 90-91
Author(s):  
Yurika Ikegami ◽  
Tomoyuki Yada ◽  
Koichi Ito ◽  
Yoshiyuki Itakura ◽  
Naomi Uemura
Keyword(s):  
Gastric Cancer ◽  
Cancer Screening ◽  
Blood Test ◽  
Gastric Cancer Screening ◽  
H Pylori

scholarly journals Diagnostic value of macrophage inhibitory cytokine 1 as a novel prognostic biomarkers for early gastric cancer screening

2020 ◽  
Author(s):  
Xin Ge ◽  
Xiaolei Zhang ◽  
Yanling Ma ◽  
Shaohua Chen ◽  
Zhaowu Chen ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Cancer Diagnosis ◽  
Early Stage ◽  
Precancerous Lesions ◽  
Diagnostic Value ◽  
Low Grade ◽  
Serum Samples ◽  
Early Screening ◽  
Roc Curve Analysis

Abstract BACKGROUND Early diagnosis is very important to improve the survival rate of patients with gastric cancer, especially in asymptomatic participants. However, low sensitivity of common biomarkers has caused difficulties in early screening of gastric cancer. In this study, we explored whether MIC-1 can improve the detection rate of early gastric cancer.METHODS We screened 8,257 participants based on risk factors such as age, gender, and family history for physical examination including gastroscopy. Participant blood samples were taken for measure MIC-1, CA-199, CA72-4 and PG1/PG2 levels. The diagnostic performance of MIC-1 was assessed and compared with CA-199, CA72-4 and PG1/PG2, and its role in early gastric cancer diagnosis and the assessment of the risk of precancerous lesions have also been studied.RESULTS Based on endoscopic and histopathological findings, 55 participants had gastric cancer, 566 participants had low-grade neoplasia, 2605 participants had chronic gastritis. MIC-1 levels were significantly elevated in gastric cancer serum samples as compared to controls (p<0.001). The sensitivity of serum MIC-1 for gastric cancer diagnosis was much higher than that of CA-199 (49.1% vs. 20.0%) with similar specificities. Moreover, receiver operating characteristic (ROC) curve analysis also showed that serum MIC-1 had a better performance compared with CA-199, CA72-4 and PG1/PG2 in distinguishing early-stage gastric cancer (AUC: 72.9% vs. 69.5%, 67.5%, 44.0% respectively).CONCLUSIONS Serum MIC-1 is significantly elevated in most patients with early gastric cancer. MIC-1 can serve as a novel diagnostic marker of early gastric cancer and value the risk of gastric cancer.

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