The dual role of KCNQ/M channels upon OGD or OGD/R insults in cultured cortical neurons of mice: Timing is crucial in targeting M‐channels against ischemic injur ies

2018 ◽  
Vol 234 (8) ◽  
pp. 12714-12726
Author(s):  
Yu Diao ◽  
Weijie Yan ◽  
Wei Sun ◽  
Yanlin Luo ◽  
Junfa Li ◽  
...  
Keyword(s):  
Cortical Neurons ◽  
Dual Role ◽  
Cultured Cortical Neurons ◽  
M Channels

scholarly journals A dual role of EphB1/ephrin-B3 reverse signaling on migrating striatal and cortical neurons originating in the preoptic area: should I stay or go away?

2014 ◽  
Vol 8 ◽  
Author(s):  
Judith Rudolph ◽  
Katrin Gerstmann ◽  
Geraldine Zimmer ◽  
André Steinecke ◽  
Annika Döding ◽  
...  
Keyword(s):  
Cortical Neurons ◽  
Preoptic Area ◽  
Dual Role ◽  
Reverse Signaling

scholarly journals Concentration-Dependent Dual Role of Thrombin in Protection of Cultured Rat Cortical Neurons

2015 ◽  
Vol 40 (11) ◽  
pp. 2220-2229 ◽  
Author(s):  
Paul S. García ◽  
Vincent T. Ciavatta ◽  
Jonathan A. Fidler ◽  
Anna Woodbury ◽  
Jerrold H. Levy ◽  
...  
Keyword(s):  
Cortical Neurons ◽  
Dual Role ◽  
Rat Cortical Neurons

P3-077: Protective role of n-trans-feruloyltyramine against beta-amyloid-peptide-induced neurotoxicity, bax, caspase and ROS in rat-cultured cortical neurons

2012 ◽  
Vol 8 (4S_Part_13) ◽  
pp. P479-P480
Author(s):  
Wipawan Thangnipon ◽  
Nirut Suwanna ◽  
Narisorn Kitiyanant ◽  
Rungtip Soi-ampornkul ◽  
Bamroong Munyoo ◽  
...  
Keyword(s):  
Cortical Neurons ◽  
Beta Amyloid ◽  
Protective Role ◽  
Amyloid Peptide ◽  
Beta Amyloid Peptide ◽  
Cultured Cortical Neurons

scholarly journals Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

2006 ◽  
Vol 175 (2) ◽  
pp. 209-215 ◽  
Author(s):  
Yinghua Ma ◽  
Jianxue Li ◽  
Isaac Chiu ◽  
Yawen Wang ◽  
Jacob A. Sloane ◽  
...  
Keyword(s):  
Immune Responses ◽  
Neurite Outgrowth ◽  
Cortical Neurons ◽  
Neuronal Apoptosis ◽  
Negative Regulator ◽  
Toll Like Receptor ◽  
Neuronal Responses ◽  
Adaptive Immune ◽  
Cultured Cortical Neurons

Toll receptors in Drosophila melanogaster function in morphogenesis and host defense. Mammalian orthologues of Toll, the Toll-like receptors (TLRs), have been studied extensively for their essential functions in controlling innate and adaptive immune responses. We report that TLR8 is dynamically expressed during mouse brain development and localizes to neurons and axons. Agonist stimulation of TLR8 in cultured cortical neurons causes inhibition of neurite outgrowth and induces apoptosis in a dissociable manner. Our evidence indicates that such TLR8-mediated neuronal responses do not involve the canonical TLR–NF-κB signaling pathway. These findings reveal novel functions for TLR8 in the mammalian nervous system that are distinct from the classical role of TLRs in immunity.

scholarly journals Role of the Outward Delayed Rectifier K+ Current in Ceramide-Induced Caspase Activation and Apoptosis in Cultured Cortical Neurons

2001 ◽  
Vol 73 (3) ◽  
pp. 933-941 ◽  
Author(s):  
Shan Ping Yu ◽  
Chen-Hsiung Yeh ◽  
Frank Gottron ◽  
Xin Wang ◽  
Margaret C. Grabb ◽  
...  
Keyword(s):  
Cortical Neurons ◽  
Delayed Rectifier ◽  
Caspase Activation ◽  
Cultured Cortical Neurons ◽  
K Current

Role of potassium channels in Aβ1–40-activated apoptotic pathway in cultured cortical neurons

2006 ◽  
Vol 84 (7) ◽  
pp. 1475-1484 ◽  
Author(s):  
Hai-bo Yu ◽  
Zheng-bin Li ◽  
Hai-xia Zhang ◽  
Xiao-liang Wang
Keyword(s):  
Potassium Channels ◽  
Cortical Neurons ◽  
Apoptotic Pathway ◽  
Cultured Cortical Neurons
Sign in / Sign up

Export Citation Format

Share Document