Histological evaluation on bone regeneration of dental implant placement sites grafted with a self-setting α-tricalcium phosphate cement

2008 ◽  
Vol 71 (2) ◽  
pp. 93-104 ◽  
Author(s):  
Masayoshi Nakadate ◽  
Norio Amizuka ◽  
Minqi Li ◽  
Paulo H.L. Freitas ◽  
Kimimitsu Oda ◽  
...  
2013 ◽  
Vol 102 (5) ◽  
pp. 1379-1388 ◽  
Author(s):  
Bee Tin Goh ◽  
Nattharee Chanchareonsook ◽  
Henk Tideman ◽  
Swee Hin Teoh ◽  
James Kwok Fai Chow ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Bruno Freitas Mello ◽  
Márcio de Carvalho Formiga ◽  
Luiz Fernando de Souza da Silva ◽  
Gustavo dos Santos Coura ◽  
Jamil Awad Shibli

The guided bone regeneration (GBR) technique has been used to achieve optimal bone volume augmentation and allow dental implant placement in atrophic maxilla and mandible, with predictable results and high survival rates. The use of bone substitutes has reduced the necessity of autogenous bone grafts, reducing the morbidity at the donor areas and thus improving the patients’ satisfaction and comfort. This clinical case report shows a clinical and histological evaluation of the bone tissue behavior, in a case that required the horizontal augmentation of the alveolar ridge, with the use of xenograft biomaterial and further dental implant placement. After six months of healing time, six implants were placed, and a bone biopsy was done. The histological analysis depicted some fragments of the xenograft bone graft, integrated with the new-formed bone tissue.


Symmetry ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1356
Author(s):  
Elizabeth Ferreira Martinez ◽  
Ana Elisa Amaro Rodrigues ◽  
Lucas Novaes Teixeira ◽  
Andrea Rodrigues Esposito ◽  
Walter Israel Rojas Cabrera ◽  
...  

Background: The use of biomaterials is commonplace in dentistry for bone regeneration. The aim of this study was to evaluate the performance of a new alloplastic material for bone repair in critical defects and to evaluate the extent of the inflammatory process. Methods: Forty-five New Zealand rabbits were divided into five groups according to evaluation time (7, 14, 30, 60, 120 days), totaling 180 sites with six-millimeter diameter defects in their tibiae. The defects were filled with alloplastic material consisting of poly (lactide-co-caprolactone), beta-tricalcium phosphate, hydroxyapatite and nano-hydroxyapatite (BTPHP) in three different presentations: paste, block, and membrane. Comparisons were established with reference materials, such as Bio-ossTM, Bio-oss CollagenTM, and Bio-gideTM, respectively. The samples were HE-stained and evaluated for inflammatory infiltrate (scored for intensity from 0 to 3) and the presence of newly formed bone at the periphery of the defects. Results: Greater bone formation was observed for the alloplastic material and equivalent inflammatory intensity for both materials, regardless of evaluation time. At 30 days, part of the synthetic biomaterial, regardless of the presentation, was resorbed. Conclusions: We concluded that this novel alloplastic material showed osteoconductive potential, biocompatibility, low inflammatory response, and gradual resorption, thus an alternative strategy for guided bone regeneration.


2021 ◽  
Vol 5 (3) ◽  
pp. 144-146
Author(s):  
Shamila Shetty K ◽  
◽  
R.K Nishith ◽  
R.K Nishith ◽  
Misha Rose Mathew ◽  
...  

The main biological and biophysical process that has made dental implant therapy predictably successful for replacing missing teeth is Osseointegration. Teeth extraction is done for several purposes, often without any consideration for the preservation of the alveolar ridge. Alveolar bone post-extraction changes have been estimated to cause a 50% decrease in alveolar bone buccolingual width, and a further loss in height. This review will go through various techniques of ARP and bone regeneration techniques and explore the best way to obtain the best outcomes after implant placement.


2017 ◽  
Vol 26 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Yasuko Takahashi ◽  
Miwa Kanou ◽  
Yuichi Ito ◽  
Michi Ohmori ◽  
Kayoko Yamamoto ◽  
...  

Author(s):  
Carlo Mangano ◽  
Alessandra Giuliani ◽  
Ilaria De Tullio ◽  
Mario Raspanti ◽  
Adriano Piattelli ◽  
...  

Introduction: Dental implant placement can be challenging when insufficient bone volume is present and bone augmentation procedures are indicated. The purpose was to assess clinically and histologically a specimen of 30%HA-60%β-TCP BCP 3D-printed scaffold, after 7-years.Case Description: The patient underwent bone regeneration of maxillary buccal plate with 3D-printed biphasic-HA block in 2013. After 7-years, a specimen of the regenerated bone was harvested and processed to perform microCT and histomorphometrical analyses.Results: The microarchitecture study performed by microCT in the test-biopsy showed that biomaterial volume decreased more than 23% and that newly-formed bone volume represented more than 57% of the overall mineralized tissue. Comparing with unloaded controls or peri-dental bone, Test-sample appeared much more mineralized and bulky. Histological evaluation showed complete integration of the scaffold and signs of particles degradation. The percentage of bone, biomaterials and soft tissues was, respectively, 59.2, 25.6, and 15.2%. Under polarized light microscopy, the biomaterial was surrounded by lamellar bone. These results indicate that, while unloaded jaws mimicked the typical osteoporotic microarchitecture after 1-year without loading, the BCP helped to preserve a correct microarchitecture after 7-years.Conclusions: BCP 3D-printed scaffolds represent a suitable solution for bone regeneration: they can lead to straightforward and less time-consuming surgery, and to bone preservation.


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