A novel multi‐nutrient human milk based human milk fortifier promotes growth and tolerance in premature infants

Author(s):  
Amy Gates ◽  
Amy B. Thompson ◽  
Terri Marin ◽  
Jennifer L. Waller ◽  
Jenny Patel ◽  
...  

2017 ◽  
Vol 34 (14) ◽  
pp. 1411-1416 ◽  
Author(s):  
Ranjan Monga ◽  
Venkatesh Sampath ◽  
Barb Ehrhart ◽  
Navin Kumar

Objective To compare growth and metabolic outcomes of premature infants receiving either Enfamil liquid human milk fortifier (ELHMF) or Similac liquid human milk fortifier (SLHMF). Study Design Infants born at ≤31 weeks' gestational age (GA) with birth weights <1,500 g and exclusively fed on human milk (mother's milk and/or donor milk) were prospectively assigned alternatively to one of the two liquid human milk fortifier (LHMF) groups. Baseline demographic, growth, enteral nutrition, and laboratory data were compared after fortification. Results In total, 31 preterm infants were recruited (ELHMF = 16; SLHMF = 15) with a mean GA of 27.1 ± 2.1 weeks and birth weight of 993 ± 245 g. The SLHMF group had significantly better weight gain as measured by individual weight z-scores (p = 0.008), better median weight gain velocity (p = 0.014), and less metabolic acidosis (p = 0.016). Overall weight gain was significantly better on mother's own milk in both the fortifier groups. The SLHMF group showed a trend toward higher growth velocity on donor milk compared with ELHMF (p = 0.06). We also observed a higher reticulocyte count (p = 0.003) in the SLHMF group compared with the ELHMF group. Conclusion In premature infants, between the two liquid human milk fortifiers, ELHMF fortifier is associated with relatively less weight gain and more metabolic acidosis.



1998 ◽  
Vol 43 ◽  
pp. 265-265
Author(s):  
Gloria J Moody ◽  
Richard J Schanler ◽  
Robert J Shulman ◽  
Chantal Lau


Nutrients ◽  
2016 ◽  
Vol 8 (8) ◽  
pp. 451 ◽  
Author(s):  
Melissa Thoene ◽  
Elizabeth Lyden ◽  
Kara Weishaar ◽  
Elizabeth Elliott ◽  
Ruomei Wu ◽  
...  






2006 ◽  
Vol 26 (12) ◽  
pp. 761-763 ◽  
Author(s):  
F Ovalı ◽  
İH Çiftçi ◽  
Z Çetinkaya ◽  
A Bükülmez


2013 ◽  
Vol 89 (4) ◽  
pp. 394-399
Author(s):  
Leticia Fuganti Campos ◽  
João Carlos Domingues Repka ◽  
Mário Cícero Falcão


PEDIATRICS ◽  
1962 ◽  
Vol 30 (6) ◽  
pp. 909-916
Author(s):  
Herbert I. Goldman ◽  
Samuel Karelitz ◽  
Hedda Acs ◽  
Eli Seifter

One hundred four healthy premature infants, of birth weight 1,000 to 1,800 gm, were fed one of five feedings: (1) human milk; (2) human milk plus 13 meq/l of sodium chloride; (3) human milk plus 13 meq/l of sodium chloride and 18 meq/l of potassium chloride; (4) a half-skimmed cows milk formula; and (5) a partially-skimmed vegetable oil, cows milk formula. The infants fed any of the three human milk formulas gained weight at a slower rate than the infants fed either of the two cows milk formulas. Infants whose diets were changed from unmodified human milk to the half-skimmed cows milk gained large amounts of weight, and at times were visibly edematous. Infants whose diets were changed from the human milks with added sodium chloride, to the half-skimmed cows milk, gained lesser amounts of weight and did not become edematous. The infants fed the two cows milk diets gained similar amounts of weight, although one diet provided 6.5 gm/kg/day, the other 3.1 gm/kg/day of protein.



1982 ◽  
Vol 81 (5) ◽  
pp. 547-553 ◽  
Author(s):  
Mary Sue Brady ◽  
Karyl A. Rickard ◽  
Judith A. Ernst ◽  
Richard L. Schreiner ◽  
James A. Lemons


Sign in / Sign up

Export Citation Format

Share Document