scholarly journals Effect of two cosmetic compounds on the growth, biofilm formation activity, and surface properties of acneic strains of Cutibacterium acnes and Staphylococcus aureus

2018 ◽  
Vol 8 (3) ◽  
pp. e00659 ◽  
Author(s):  
Andrei V. Gannesen ◽  
Valerie Borrel ◽  
Luc Lefeuvre ◽  
Alexander I. Netrusov ◽  
Vladimir K. Plakunov ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Surface Properties ◽  
Biofilm Formation ◽  
Cutibacterium Acnes ◽  
And Staphylococcus Aureus

Rutin inhibits mono and multi-species biofilm formation by foodborne drug resistant Escherichia coli and Staphylococcus aureus

Food Control ◽  
2017 ◽  
Vol 79 ◽  
pp. 325-332 ◽  
Author(s):  
Nasser Abdulatif Al-Shabib ◽  
Fohad Mabood Husain ◽  
Iqbal Ahmad ◽  
Mohd Shahnawaz Khan ◽  
Rais Ahmad Khan ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Biofilm Formation ◽  
Drug Resistant ◽  
And Staphylococcus Aureus

Do Cutibacterium acnes and Staphylococcus aureus define two different types of folliculitis?

2018 ◽  
Vol 32 (7) ◽  
pp. e266-e268 ◽  
Author(s):  
C. Frenard ◽  
M-A. Dagnelie ◽  
A. Khammari ◽  
M. Saint-Jean ◽  
A. Boisrobert ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cutibacterium Acnes ◽  
Different Types ◽  
And Staphylococcus Aureus

scholarly journals Oral Administration of the Broad-Spectrum Antibiofilm Compound Toremifene Inhibits Candida albicans and Staphylococcus aureus Biofilm FormationIn Vivo

2014 ◽  
Vol 58 (12) ◽  
pp. 7606-7610 ◽  
Author(s):  
Kaat De Cremer ◽  
Nicolas Delattin ◽  
Katrijn De Brucker ◽  
Annelies Peeters ◽  
Soña Kucharíková ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Broad Spectrum ◽  
Staphylococcus Epidermidis ◽  
Biofilm Formation ◽  
Candida Krusei ◽  
Content Type ◽  
And Staphylococcus Aureus

ABSTRACTWe here report on thein vitroactivity of toremifene to inhibit biofilm formation of different fungal and bacterial pathogens, includingCandida albicans,Candida glabrata,Candida dubliniensis,Candida krusei,Pseudomonas aeruginosa,Staphylococcus aureus, andStaphylococcus epidermidis. We validated thein vivoefficacy of orally administered toremifene againstC. albicans and S. aureusbiofilm formation in a rat subcutaneous catheter model. Combined, our results demonstrate the potential of toremifene as a broad-spectrum oral antibiofilm compound.

Gentamicin release from polymethylmethacrylate bone cements and Staphylococcus aureus biofilm formation

2000 ◽  
Vol 71 (6) ◽  
pp. 625-629 ◽  
Author(s):  
Hilbrand van De Belt ◽  
Daniëlle Neut ◽  
Willem Schenk ◽  
Jim R van Horn ◽  
Henny C van Der Mei ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Biofilm Formation ◽  
Bone Cements ◽  
And Staphylococcus Aureus

Interaction of implant infection-related commensal bacteria with mesenchymal stem cells: A comparison between Cutibacterium acnes and Staphylococcus aureus

2021 ◽  
Author(s):  
Taghrid S El-Mahdy ◽  
Céline Mongaret ◽  
Jennifer Varin-Simon ◽  
Fabien Lamret ◽  
Véronique Vernet-Garnier ◽  
...  
Keyword(s):  
Stem Cells ◽  
Staphylococcus Aureus ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Regenerative Process ◽  
Bacterial Biofilm ◽  
Biofilm Production ◽  
Cutibacterium Acnes ◽  
Live Bacteria ◽  
And Staphylococcus Aureus

Abstract Staphylococcus aureus and Cutibacterium acnes are involved in several tissue infections and can encounter mesenchymal stem cells (MSCs) during their role in tissue regenerative process. C. acnes and S. aureus internalization by three types of MSCs derived from bone marrow, dental pulp and Wharton's jelly; and bacterial biofilm production were compared. Internalization rates ranged between 1.7%-6.3% and 0.8%-2.7% for C. acnes and S. aureus, respectively. While C. acnes strains exhibited limited cytotoxic effect on MSCs, S. aureus were more virulent with marked effect starting after only three hours of interaction. Both bacteria were able to produce biofilms with respectively aggregated and monolayered structures for C. acnes and S. aureus. The increase in C. acnes capacity to develop biofilm following MSCs’ internalization was not linked to the significant increase in number of live bacteria, except for bone marrow-MSCs/C. acnes CIP 53.117 with 79% live bacteria compared to the 36% before internalization. On the other hand, internalization of S. aureus had no impact on its ability to form biofilms composed mainly of living bacteria. The present study underlined the complexity of MSCs-bacteria cross-interaction and brought insights into understanding the MSCs behaviour in response to bacterial infection in tissue regeneration context.

scholarly journals Inhibition of Biofilm Formation by Esomeprazole in Pseudomonas aeruginosa and Staphylococcus aureus

2012 ◽  
Vol 56 (8) ◽  
pp. 4360-4364 ◽  
Author(s):  
Vandana Singh ◽  
Vaneet Arora ◽  
M. Jahangir Alam ◽  
Kevin W. Garey
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Bacterial Growth ◽  
Biofilm Formation ◽  
Antimicrobial Properties ◽  
Antibiofilm Activity ◽  
Biofilm Growth ◽  
Content Type ◽  
Conventional Antibiotics ◽  
And Staphylococcus Aureus

ABSTRACTStaphylococcus aureusandPseudomonas aeruginosaare common nosocomial pathogens responsible for biofilm-associated infections. Proton pump inhibitors (PPI), such as esomeprazole, may have novel antimicrobial properties. The objective of this study was to assess whether esomeprazole prevents sessile bacterial growth and biofilm formation and whether it may have synergistic killing effects with standard antibiotics. The antibiofilm activity of esomeprazole at 0.25 mM was tested against two strains each ofS. aureusandP. aeruginosa. Bacterial biofilms were prepared using a commercially available 96-peg-plate Calgary biofilm device. Sessile bacterial CFU counts and biomass were assessed during 72 hours of esomeprazole exposure. The killing activities after an additional 24 hours of vancomycin (againstS. aureus) and meropenem (againstP. aeruginosa) treatment with or without preexposure to esomeprazole were also assessed by CFU and biomass analyses.P. aeruginosaandS. aureusstrains exposed to esomeprazole displayed decreased sessile bacterial growth and biomass (P< 0.001, each parameter). After 72 h of exposure, there was a 1-log10decrease in the CFU/ml of esomeprazole-exposedP. aeruginosaandS. aureusstrains compared to controls (P< 0.001). After 72 h of exposure, measured absorbance was 100% greater inP. aeruginosacontrol strains than in esomeprazole-exposed strains (P< 0.001). Increased killing and decreased biomass were observed for esomeprazole-treated bacteria compared to untreated controls exposed to conventional antibiotics (P< 0.001, each parameter). Reduced biofilm growth after 24 h was visibly apparent by light micrographs forP. aeruginosaandS. aureusisolates exposed to esomeprazole compared to untreated controls. In conclusion, esomeprazole demonstrated an antibiofilm effect against biofilm-producingS. aureusandP. aeruginosa.

scholarly journals Anti-Biofilm Effects of Synthetic Antimicrobial Peptides Against Drug-Resistant Pseudomonas aeruginosa and Staphylococcus aureus Planktonic Cells and Biofilm

Molecules ◽  
2019 ◽  
Vol 24 (24) ◽  
pp. 4560 ◽  
Author(s):  
Seong-Cheol Park ◽  
Min-Young Lee ◽  
Jin-Young Kim ◽  
Hyeonseok Kim ◽  
Myunghwan Jung ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Peptides ◽  
Biofilm Formation ◽  
Extracellular Dna ◽  
Therapeutic Drug ◽  
Dependent Manner ◽  
Drug Resistant ◽  
And Staphylococcus Aureus

Biofilm-associated infections are difficult to manage or treat as biofilms or biofilm-embedded bacteria are difficult to eradicate. Antimicrobial peptides have gained increasing attention as a possible alternative to conventional drugs to combat drug-resistant microorganisms because they inhibit the growth of planktonic bacteria by disrupting the cytoplasmic membrane. The current study investigated the effects of synthetic peptides (PS1-2, PS1-5, and PS1-6) and conventional antibiotics on the growth, biofilm formation, and biofilm reduction of drug-resistant Pseudomonas aeruginosa and Staphylococcus aureus. The effects of PS1-2, PS1-5, and PS1-6 were also tested in vivo using a mouse model. All peptides inhibited planktonic cell growth and biofilm formation in a dose-dependent manner. They also reduced preformed biofilm masses by removing the carbohydrates, extracellular DNA, and lipids that comprised extracellular polymeric substances (EPSs) but did not affect proteins. In vivo, PS1-2 showed the greatest efficacy against preformed biofilms with no cytotoxicity. Our findings indicate that the PS1-2 peptide has potential as a next-generation therapeutic drug to overcome multidrug resistance and to regulate inflammatory response in biofilm-associated infections.

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