Mathematical modeling of a temperature‐sensitive and tissue‐mimicking gel matrix: Solving the Flory–Huggins equation for an elastic ternary mixture system

During hibernation, animals cycle between torpor and arousal. These cycles involve dramatic but poorly understood mechanisms of dynamic physiological regulation at the level of gene expression. Each cycle, Brown Adipose Tissue (BAT) drives periodic arousal from torpor by generating essential heat. We applied digital transcriptome analysis to precisely timed samples to identify molecular pathways that underlie the intense activity cycles of hibernator BAT. A cohort of transcripts increased during torpor, paradoxical because transcription effectively ceases at these low temperatures. We show that this increase occurs not by elevated transcription but rather by enhanced stabilization associated with maintenance and/or extension of long poly(A) tails. Mathematical modeling further supports a temperature-sensitive mechanism to protect a subset of transcripts from ongoing bulk degradation instead of increased transcription. This subset was enriched in a C-rich motif and genes required for BAT activation, suggesting a model and mechanism to prioritize translation of key proteins for thermogenesis.

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Phase behaviour of the ternary mixture system of poly(l-lactic acid), dichloromethane and carbon dioxide

The Journal of Chemical Thermodynamics ◽

10.1016/j.jct.2012.06.011 ◽

2012 ◽

Vol 55 ◽

pp. 37-41 ◽

Cited By ~ 8

Author(s):

Jungmin Gwon ◽

Dong Woo Cho ◽

Soo Hyeon Kim ◽

Hun Yong Shin ◽

Hwayong Kim

Keyword(s):

Carbon Dioxide ◽

Lactic Acid ◽

Ternary Mixture ◽

Phase Behaviour ◽

Mixture System

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Conveyor-Belt Dryers with Tangential Flow for Food Drying: Mathematical Modeling and Design Guidelines for Final Moisture Content Higher Than the Critical Value

Inventions ◽

10.3390/inventions5020022 ◽

2020 ◽

Vol 5 (2) ◽

pp. 22

Author(s):

Dario Friso

Keyword(s):

Mathematical Modeling ◽

Moisture Content ◽

Rational Design ◽

Conveyor Belt ◽

Design Guidelines ◽

Final Moisture Content ◽

Temperature Sensitive ◽

Optimized Design ◽

Tangential Flow ◽

Product Flow

The mathematical modeling presented in this work concerns the conveyor-belt dryer with the tangential flow of air with respect to food. This dryer, if operating in co-current, has the advantage of well preserving the organoleptic and nutritional qualities of the dried product. In fact, it has a low air temperature in the final stretch where the product has low moisture content and is therefore more temperature sensitive. It is a bulkier dryer than the continuous through-circulation conveyor dryer with a perforated belt. The latter is therefore more frequently used and has received greater study attention from researchers and designers of the industry. With the aim to propose guidelines for a rational design of the conveyor-belt dryer with tangential flow, a mathematical model was developed here through the differentiation of the drying rate equation followed by its integration performed along the dryer belt. Consequently, and with the assumption that the final moisture content XF of the product is higher than the critical moisture content XC, the relationships between the intensive quantities (temperatures, humidity and enthalpies), the extensive quantities (air and product flow rates) and the dimensional ones (length and width of the belt), were obtained. Finally, on the basis of these relationships, the rules for an optimized design for XF > XC were obtained and experimentally evaluated.

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Mathematical modeling of a temperature-sensitive and tissue-mimicking gel matrix

Authorea ◽

10.22541/au.158074344.43438508 ◽

2020 ◽

Author(s):

Baeckkyoung SUNG

Keyword(s):

Mathematical Modeling ◽

Temperature Sensitive

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FTIR Spectroscopy Combined with Partial Least Square for Analysis of Red Fruit Oil in Ternary Mixture System

International Journal of Spectroscopy ◽

10.1155/2014/785914 ◽

2014 ◽

Vol 2014 ◽

pp. 1-5 ◽

Cited By ~ 9

Author(s):

A. Rohman ◽

Dwi Larasati Setyaningrum ◽

Sugeng Riyanto

Keyword(s):

Ftir Spectroscopy ◽

Ternary Mixture ◽

Edible Oils ◽

Ftir Spectra ◽

Partial Least Square ◽

Least Square ◽

Reliable Technique ◽

Fruit Oil ◽

Mixture System

FTIR spectroscopy is a promising method for quantification of edible oils. Three edible oils, namely, red fruit oil (RFO), corn oil (CO), and soybean oil (SO), in ternary mixture system were quantitatively analyzed using FTIR spectroscopy in combination with partial least square (PLS). FTIR spectra of edible oils in ternary mixture were subjected to several treatments including normal spectra and their derivative. Using PLS calibration, the first derivative FTIR spectra can be exploited for determination of RFO; meanwhile, the second derivative spectra were preferred for determination of CO and SO. The R2 values obtained for the relationship between actual and FTIR predicted values of RFO, CO, and SO were 0.9863, 0.9276, and 0.9693, respectively. The root mean square error of calibration (RMSEC) values obtained were 1.59, 1.72, and 1.60% (v/v) for RFO, CO, and SO, respectively. The result showed that FTIR spectroscopy offers accurate and reliable technique for quantitative analysis of RFO, CO, and SO simultaneously in ternary mixture systems. Besides, the developed method can be extended for analysis of CO and SO as adulterants in RFO.

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Optimization of Organosolv Based Fractionation Process for Separation of High Purity Lignin from Bagasse

Materials Science Forum ◽

10.4028/www.scientific.net/msf.883.92 ◽

2017 ◽

Vol 883 ◽

pp. 92-96

Author(s):

Sawitree Cheiwpanich ◽

Navadol Laosiripojana ◽

Verawat Champreda

Keyword(s):

Ternary Mixture ◽

Low Cost ◽

Solvent Mixture ◽

Aqueous Alcohol ◽

Lignocellulosic Materials ◽

Fractionation Process ◽

Glucose Yield ◽

Renewable Source ◽

Organic Fractions ◽

Mixture System

Lignocellulosic biomass is a renewable source for sustainable production of fuels, chemicals, and other materials with the advantages on its carbon-neutral nature. Fractionation of lignocellulosic materials is a pre-requisite in the biorefinery process in order to convert the cellulose, hemicellulose, and lignin to valuable products with maximized economics prospective. In this work, a modified clean fractionation (CF) process using ternary mixture system of ethyl acetate/methanol/water was studied with the use of acid promoters. H2SO4 was found to be the efficient promoter due to low cost compare to other acid promoters. The optimal fractionation conditions operated in the solvent mixture containing 0.025 M H2SO4 at 160°C for 50 min led to 63.72% recovery of the cellulose in the solid pulp while 90% and 59.94% of hemicellulose-derived products and lignin were recovered in the aqueous-alcohol and organic fractions, respectively. The enzymatic digestibility of the cellulose-enriched pulp was increased, resulting increasing glucose yield from 38.32% of the native biomass to 70.04% using the hydrolysis reaction with Cellic Ctech2® at 15 FPU/g. The work demonstrated the applicability of the modified CF process for fractionation of lignocellulose components for integrated biorefinery process.

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Oncogenesis and the Lucké Virus

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100100743 ◽

1968 ◽

Vol 26 ◽

pp. 200-201

Author(s):

A. E. Vatter ◽

J. Zambernard

Keyword(s):

Rna Viruses ◽

Vegetative State ◽

Temperature Sensitive ◽

Structural Level ◽

Oncogenic Viruses ◽

Dna Viruses ◽

Leopard Frogs ◽

Renal Adenocarcinoma ◽

Induced Tumors ◽

Northern Leopard Frogs

Oncogenic viruses, like viruses in general, can be divided into two classes, those that contain deoxyribonucleic acid (DNA) and those that contain ribonucleic acid (RNA). The RNA viruses have been recovered readily from the tumors which they cause whereas, the DNA-virus induced tumors have not yielded the virus. Since DNA viruses cannot be recovered, the bulk of present day investigations have been concerned with RNA viruses.The Lucké renal adenocarcinoma is a spontaneous tumor which occurs in northern leopard frogs (Rana pipiens) and has received increased attention in recent years because of its probable viral etiology. This hypothesis was first advanced by Lucké after he observed intranuclear inclusions in some of the tumor cells. Tumors with inclusions were examined at the fine structural level by Fawcett who showed that they contained immature and mature virus˗like particles.The use of this system in the study of oncogenic tumors offers several unique features, the virus has been shown to contain DNA and it can be recovered from the tumor, also, it is temperature sensitive. This latter feature is of importance because the virus can be transformed from a latent to a vegetative state by lowering or elevating the environmental temperature.

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