scholarly journals Technical Note: Enhancing soft tissue contrast and radiation-induced image changes with dual-energy CT for radiation therapy

2018 ◽  
Vol 45 (9) ◽  
pp. 4238-4245 ◽  
Author(s):  
George Noid ◽  
An Tai ◽  
Diane Schott ◽  
Nilesh Mistry ◽  
Yu Liu ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Soft Tissue ◽  
Dual Energy ◽  
Technical Note ◽  
Dual Energy Ct ◽  
Soft Tissue Contrast ◽  
Tissue Contrast ◽  
Radiation Induced

Image-guided radiation therapy using computed tomography in radiotherapy

2010 ◽  
Vol 10 (2) ◽  
pp. 121-136 ◽  
Author(s):  
Winky Wing Ki Fung ◽  
Vincent Wing Cheung Wu
Keyword(s):  
Computed Tomography ◽  
Radiation Therapy ◽  
Soft Tissue ◽  
Image Guidance ◽  
Cone Beam ◽  
Patient Specific ◽  
Image Guided Radiotherapy ◽  
Soft Tissue Contrast ◽  
Image Guided ◽  
Tissue Contrast

AbstractThe sharp dose gradients in intensity-modulated radiation therapy increase the treatment sensitivity to various inter- and intra-fractional uncertainties, in which a slight anatomical change may greatly alter the actual dose delivered. Image-guided radiotherapy refers to the use of advanced imaging techniques to precisely track and correct these patient-specific variations in routine treatment. It can also monitor organ changes during a radiotherapy course. Currently, image-guided radiotherapy using computed tomography has gained much popularity in radiotherapy verification as it provides volumetric images with soft-tissue contrast for on-line tracking of tumour. This article reviews four types of computed tomography-based image guidance systems and their working principles. The system characteristics and clinical applications of the helical, megavoltage, computed tomography, and kilovoltage, cone-beam, computed tomography systems are discussed, given that they are currently the most commonly used systems for radiotherapy verification. This article also focuses on the recent techniques of soft-tissue contrast enhancement, digital tomosynthesis, four-dimensional fluoroscopic image guidance, and kilovoltage/megavoltage, in-line cone-beam imaging. These evolving systems are expected to take over the conventional two-dimensional verification system in the near future and provide the basis for implementing adaptive radiotherapy.

TH-CD-202-03: Enhancing Soft-Tissue CT Contrast for Radiation Therapy Using Mono-Energetic Decompositions of Dual Energy CT

2016 ◽  
Vol 43 (6Part45) ◽  
pp. 3876-3877
Author(s):  
G Noid ◽  
A Tai ◽  
Y Liu ◽  
X Li
Keyword(s):  
Radiation Therapy ◽  
Soft Tissue ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Ct Contrast

scholarly journals First Asian population study of stereotactic body radiation therapy for ventricular arrhythmias

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Li-Ting Ho ◽  
Jenny Ling-Yu Chen ◽  
Hsing-Min Chan ◽  
Yu-Cheng Huang ◽  
Mao-Yuan Su ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Three Dimensional ◽  
Asian Population ◽  
Target Volume ◽  
Dual Energy ◽  
Detection Sensitivity ◽  
Dual Energy Ct ◽  
Stereotactic Body Radiation ◽  
Integrated Boost ◽  
Monitoring Treatment

AbstractWe report the first Asian series on stereotactic body radiation (SBRT) for refractory ventricular arrhythmia (VA) in Taiwanese patients. Three-dimensional electroanatomic maps, delayed-enhancement magnetic resonance imaging (DE-MRI), and dual-energy computed tomography (CT) were used to identify scar substrates. The main target volume was treated with a single radiation dose of 25 Gy and the margin volume received 20 Gy using simultaneous integrated boost delivered by the Varian TrueBeam system. Efficacy was assessed according to VA events recorded by an implantable cardioverter-defibrillator (ICD) or a 24-h Holter recorder. Pre- and post-radiation therapy imaging studies were performed. From February 2019 to December 2019, seven patients (six men, one woman; mean age, 55 years) were enrolled and treated. One patient died of hepatic failure. In the remaining six patients, at a median follow-up of 14.5 months, the VA burden and ICD shocks significantly decreased (only one patient with one ICD shock after treatment). Increased intensity on DE-MRI might be associated with a lower risk for VA recurrence, whereas dual-energy CT had lower detection sensitivity. No acute or minimal late adverse events occurred. In patients with refractory VA, SBRT is associated with a marked reduction in VA burden and ICD shocks, and DE-MRI might be useful for monitoring treatment effects.

scholarly journals Investigating a novel split-filter dual-energy CT technique for improving pancreas tumor visibility for radiation therapy

2018 ◽  
Vol 19 (5) ◽  
pp. 676-683 ◽  
Author(s):  
Lianna D. Di Maso ◽  
Jessie Huang ◽  
Michael F. Bassetti ◽  
Larry A. DeWerd ◽  
Jessica R. Miller
Keyword(s):  
Radiation Therapy ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Ct Technique ◽  
Pancreas Tumor

Soft-tissue contrast resolution within the head of human cadaver by means of flat-detector-based cone-beam CT

2004 ◽  
Author(s):  
Jens Wiegert ◽  
Matthias Bertram ◽  
Dirk Schaefer ◽  
Norbert Conrads ◽  
Niels Noordhoek ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Cone Beam Ct ◽  
Cone Beam ◽  
Human Cadaver ◽  
Flat Detector ◽  
Contrast Resolution ◽  
Soft Tissue Contrast ◽  
Tissue Contrast

scholarly journals New Updates of the Imaging Role in Diagnosis, Staging, and Response Treatment of Malignant Pleural Mesothelioma

Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4377
Author(s):  
Chiara Romei ◽  
Salvatore Claudio Fanni ◽  
Federica Volpi ◽  
Alessio Milazzo ◽  
Caterina Aida D’Amore ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Malignant Pleural Mesothelioma ◽  
Therapy Response ◽  
Staging System ◽  
Clinical Settings ◽  
Pleural Mesothelioma ◽  
Soft Tissue Contrast ◽  
Diffusion Weighted Images ◽  
Tissue Contrast ◽  
Computer Based

Malignant pleural mesothelioma is a rare neoplasm with poor prognosis. CT is the first imaging technique used for diagnosis, staging, and assessment of therapy response. Although, CT has intrinsic limitations due to low soft tissue contrast and the current staging system as well as criteria for evaluating response, it does not consider the complex growth pattern of this tumor. Computer-based methods have proven their potentiality in diagnosis, staging, prognosis, and assessment of therapy response; moreover, computer-based methods can make feasible tasks like segmentation that would otherwise be impracticable. MRI, thanks to its high soft tissue contrast evaluation of contrast enhancement and through diffusion-weighted-images, could replace CT in many clinical settings.

scholarly journals Technical Note: Insertion of digital lesions in the projection domain for dual-source, dual-energy CT

2017 ◽  
Vol 44 (5) ◽  
pp. 1655-1660 ◽  
Author(s):  
Andrea Ferrero ◽  
Baiyu Chen ◽  
Zhoubo Li ◽  
Lifeng Yu ◽  
Cynthia McCollough
Keyword(s):  
Dual Energy ◽  
Technical Note ◽  
Dual Energy Ct ◽  
Dual Source ◽  
Projection Domain

scholarly journals Improving Structure Delineation for Radiation Therapy Planning Using Dual-Energy CT

2020 ◽  
Vol 10 ◽  
Author(s):  
George Noid ◽  
Justin Zhu ◽  
An Tai ◽  
Nilesh Mistry ◽  
Diane Schott ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Therapy Planning ◽  
Radiation Therapy Planning

scholarly journals Combined visualization of echinoderm hard and soft parts using contrast-enhanced micro-computed tomography

Zoosymposia ◽  
2019 ◽  
Vol 15 (1) ◽  
pp. 172-191 ◽  
Author(s):  
ALEXANDER ZIEGLER
Keyword(s):  
Computed Tomography ◽  
Soft Tissue ◽  
3D Visualization ◽  
Soft Part ◽  
Three Dimensional ◽  
Ethanol Solution ◽  
Micro Computed Tomography ◽  
Soft Tissue Contrast ◽  
Contrast Enhanced ◽  
Tissue Contrast

Recent studies have shown that micro-computed tomography (µCT) must be considered one of the most suitable techniques for the non-invasive, three-dimensional (3D) visualization of metazoan hard parts. In addition, µCT can also be used to visualize soft part anatomy non-destructively and in 3D. In order to achieve soft tissue contrast using µCT based on X-ray attenuation, fixed specimens must be immersed in staining solutions that include heavy metals such as silver (Ag), molybdenum (Mo), osmium (Os), lead (Pb), or tungsten (W). However, while contrast-enhancement has been successfully applied to specimens pertaining to various higher metazoan taxa, echinoderms have thus far not been analyzed using this approach. In order to demonstrate that this group of marine invertebrates is suitable for contrast-enhanced µCT as well, the present study provides results from an application of this technique to representative species from all five extant higher echinoderm taxa. To achieve soft part contrast, freshly fixed and museum specimens were immersed in an ethanol solution containing phosphotungstic acid and then scanned using a high-resolution desktop µCT system. The acquired datasets show that the combined visualization of echinoderm soft and hard parts can be readily accomplished using contrast-enhanced µCT in all extant echinoderm taxa. The results are compared with µCT data obtained using unstained specimens, with conventional histological sections, and with data previously acquired using magnetic resonance imaging, a technique known to provide excellent soft tissue contrast despite certain limitations. The suitability for 3D visualization and modeling of datasets gathered using contrast-enhanced µCT is illustrated and applications of this novel approach in echinoderm research are discussed.

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