Effects of calcitonin and parathyroid hormone on the regulation of cabindin-D9k in the uterus, placenta, and fetal membrane of rats related to blood calcium level during late gestation

2007 ◽  
Vol 74 (9) ◽  
pp. 1188-1197 ◽  
Author(s):  
Eui-Ju Hong ◽  
Kyung-Chul Choi ◽  
Sang-Hwan Hyun ◽  
Eui-Bae Jeung

1991 ◽  
Vol 24 (3) ◽  
pp. 289-294
Author(s):  
Ryoichi Ando ◽  
Takashi Akiba ◽  
Fumiaki Marumo ◽  
Osamu Matsuda ◽  
Noriaki Matsui




1965 ◽  
Vol 209 (5) ◽  
pp. 887-890 ◽  
Author(s):  
Felix Bronner ◽  
J. -P. Aubert

Combined kinetic (Ca45) and balance (Ca40) studies of young male Sprague-Dawley rats placed on three different levels of calcium intakes (0.05, 0.5, 1.0% Ca) showed that the blood plasma calcium level, as determined by atomic absorption spectrophotometry, remained constant and invariant over a range of absorption from 4.5 to 83.4 mg Ca/day and that the pool, i.e., all the exchangeable calcium in the body, did not increase with increased absorption. Hence no direct regulatory role can be attributed to the size of the pool. Measurement of the calcium deposition and resorption rates in bone showed that the former changed only little with increasing absorption, whereas the latter decreased nearly linearly under the same conditions. Calcium resorption from bone therefore appears to play the major role in regulating the blood calcium level.



2020 ◽  
Vol 86 (2) ◽  
pp. 121-126 ◽  
Author(s):  
Veljko Strajina ◽  
Benzon M. Dy ◽  
Travis J. Mckenzie ◽  
Geoffrey B. Thompson ◽  
Melanie L. Lyden

We performed a retrospective study of our large patient cohort aiming to examine the ability to predict postthyroidectomy hypocalcemia. A retrospective review of patients who underwent total or near-total thyroidectomy at our institution between 2008 and 2018 was performed. Postoperative hypocalcemia was defined as Ca level <8.0 mg/dL (reference range: 8.9–10.1 mg/dL) within 30 days of operation. Logistic regression was used to develop models for prediction of the occurrence of postoperative hypocalcemia. Inclusion criteria were met by 1463 patients. Hypocalcemia was documented in 223 patients (15%). Models based on parathyroid hormone (PTH) levels alone had an associated receiver operator characteristic with an areas under the curve (AUC) of 0.79. There was an inverse relationship between time of measurement and PTH levels within the first two hours after thyroidectomy ( P < 0.01). When measured two to six hours after closure, the predictive ability of PTH compared favorably (AUC = 0.82) with either earlier (within the first two hours after closure, AUC = 0.79) or later measurement (6–24 hours after closure, AUC = 0.77). When measured between two and six hours postoperatively, PTH < 19 pg/mL had a sensitivity of 90 per cent and negative predictive value of 96 per cent for postoperative hypocalcemia. The model that included the PTH level, concurrently measured total blood calcium level, and time of measurement had an improved predictive ability with an AUC of 0.87. PTH level of 19 pg/mL measured two to six hours after thyroidectomy had a sensitivity of 90 per cent and a negative predictive value of 96 per cent in our cohort. The model including postoperative PTH level, calcium level, and time of measurement may further improve the ability to predict postthyroidectomy hypocalcemia.



1995 ◽  
Vol 7 (6) ◽  
pp. 1509 ◽  
Author(s):  
ME Wlodek ◽  
PW Ho ◽  
GE Rice ◽  
JM Moseley ◽  
TJ Martin ◽  
...  

To establish the changes associated with gestational age and labour status in parathyroid hormone-related protein (PTHrP) concentrations in the amniotic fluid, human amniotic fluid was collected from non-labouring and labouring women at < 37 weeks of gestation (preterm) and at term (> or = 37 weeks). PTHrP was assayed by a specific N-terminal radioimmunoassay. PTHrP concentrations in amniotic fluid obtained from non-labouring women were significantly lower at preterm (15-36 weeks; 14.1 +/- 2.5 pmol L(-1); n = 11) than at term (37-42 weeks; 39.3 +/- 7.6 pmol L(-1); n = 16; P < 0.0009). Concentrations of PTHrP in amniotic fluid obtained from labouring women were also significantly lower at preterm (27-36 week; 12.2 +/- 4.7 pmol L(-1); n = 4; P < 0.01) than at term (37-42 weeks; 63. 8 +/- 19.6 pmol L(-1); n = 9). There were no significant changes in concentration associated with labour status, either at preterm or at term. The physiological significance of elevated amniotic fluid concentrations of PTHrP has yet to be established, but the data are consistent with the suggestion that PTHrP plays a role in fetal membrane function during late gestation.





Endocrinology ◽  
1938 ◽  
Vol 22 (3) ◽  
pp. 315-321 ◽  
Author(s):  
LOUIS LEVIN ◽  
PHILIP E. SMITH


1967 ◽  
Vol 1 (3) ◽  
pp. 261-279 ◽  
Author(s):  
F. Bronner ◽  
P.J. Sammon ◽  
R.E. Stacey ◽  
B.G. Shah


2010 ◽  
Vol 9 (2) ◽  
pp. 121
Author(s):  
J.C. Bernhard ◽  
M. Crepel ◽  
G. Verhoest ◽  
K. Bensalah ◽  
J. Tostain ◽  
...  


2017 ◽  
Vol 1 (6) ◽  
Author(s):  
Meilinah Hidayat ◽  
Komang RP Wardani ◽  
Bertha M Purba ◽  
Rendhy T Apreza

Premenstrual syndrome (PMS) is complex of symptoms that occur during the luteal phase of the menstrual cycle. This study aimed to observe blood calcium levels differences between the patient and not the PMS, list the average intake of calcium / day among subjects, statistically analyze the relationship between calcium intake and blood calcium levels, and examine the effect of calcium supplementation on blood calcium levels and symptoms of PMS. We examined blood levels of calcium, analytical survey method using a cross-sectional study, experimental methods and PMS symptom questionnaires. The results showed that in the group of subjects SPM average blood calcium level, and the mean intake of calcium / day were lower than in non-PMS and showed a fairly correlation between the intake of calcium per day with blood calcium levels in SPM subjects. There is a significant relationship between increased calcium blood calcium levels and symptoms of PMS. The conclusions: 1. there are differences in blood calcium levels and 2. intake of calcium per day between patients with PMS and not PMS, 3. Calcium intake is significantly associated with calcium level in the PMS and 4. calcium supplementation affects blood calcium levels and reduce symptoms of PMS.Keywords : average calcium intake, blood calcium, calcium supplementation, Premenstrual Syndrome (PMS)



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