scholarly journals In vivo lung morphometry with accelerated hyperpolarized 3 He diffusion MRI: A preliminary study

2014 ◽  
Vol 73 (4) ◽  
pp. 1609-1614 ◽  
Author(s):  
Yulin V. Chang ◽  
James D. Quirk ◽  
Dmitriy A. Yablonskiy
Keyword(s):  
Diffusion Mri ◽  
Preliminary Study ◽  
Lung Morphometry

In Vivo Quantification Of Lung Morphometry In Healthy And Diseased Mice With Hyperpolarized 3he Diffusion MRI

2011 ◽  
Author(s):  
Jason C. Woods ◽  
Wei Wang ◽  
Dmitriy A. Yablonskiy ◽  
Rodney Kowalewski ◽  
Nguyet M. Nguyen
Keyword(s):  
Diffusion Mri ◽  
Lung Morphometry

scholarly journals In Vivo Lung Morphometry of Lymphangioleiomyomatosis Using Hyperpolarized 129Xe Diffusion MRI

2021 ◽  
Author(s):  
A.S. Bdaiwi ◽  
M.M. Hossain ◽  
M.M. Willmering ◽  
H. Wang ◽  
N. Gupta ◽  
...  
Keyword(s):  
Diffusion Mri ◽  
Hyperpolarized 129Xe ◽  
Lung Morphometry

scholarly journals Partial Decellularization for Segmental Tracheal Scaffold Tissue Engineering: A Preliminary Study in Rabbits

Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 866
Author(s):  
Luong Huu Dang ◽  
Yuan Tseng ◽  
How Tseng ◽  
Shih-Han Hung
Keyword(s):  
Mechanical Stability ◽  
Vital Staining ◽  
Potential Method ◽  
Term Survival ◽  
Long Term Survival ◽  
Cartilage Cells ◽  
Preliminary Study ◽  
Epithelial Layers

In this study, we developed a new procedure for the rapid partial decellularization of the harvested trachea. Partial decellularization was performed using a combination of detergent and sonication to completely remove the epithelial layers outside of the cartilage ring. The post-decellularized tracheal segments were assessed with vital staining, which showed that the core cartilage cells remarkably remained intact while the cells outside of the cartilage were no longer viable. The ability of the decellularized tracheal segments to evade immune rejection was evaluated through heterotopic implantation of the segments into the chest muscle of rabbits without any immunosuppressive therapy, which demonstrated no evidence of severe rejection or tissue necrosis under H&E staining, as well as the mechanical stability under stress-pressure testing. Finally, orthotopic transplantation of partially decellularized trachea with no immunosuppression treatment resulted in 2 months of survival in two rabbits and one long-term survival (2 years) in one rabbit. Through evaluations of posttransplantation histology and endoscopy, we confirmed that our partial decellularization method could be a potential method of producing low-immunogenic cartilage scaffolds with viable, functional core cartilage cells that can achieve long-term survival after in vivo transplantation.

scholarly journals Diffusion MRI microstructure models with in vivo human brain Connectome data: results from a multi-group comparison

2017 ◽  
Vol 30 (9) ◽  
pp. e3734 ◽  
Author(s):  
Uran Ferizi ◽  
Benoit Scherrer ◽  
Torben Schneider ◽  
Mohammad Alipoor ◽  
Odin Eufracio ◽  
...  
Keyword(s):  
Human Brain ◽  
Diffusion Mri ◽  
Group Comparison ◽  
Brain Connectome

scholarly journals Feasibility of balloon-based endobiliary radiofrequency ablation under cholangioscopy guidance in a swine model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tadahisa Inoue ◽  
Hiromu Kutsumi ◽  
Mayu Ibusuki ◽  
Masashi Yoneda
Keyword(s):  
Radiofrequency Ablation ◽  
Adverse Events ◽  
Swine Model ◽  
Biliary Strictures ◽  
Tissue Samples ◽  
Ablation Area ◽  
Mucosal Changes ◽  
The Mean ◽  
Preliminary Study

AbstractAlthough endobiliary radiofrequency ablation (RFA) has demonstrated considerable potential for the treatment of biliary strictures, conventional catheter RFA has several limitations. This study aimed to evaluate the feasibility of a novel cholangioscopy (CS)-guided balloon-based RFA procedure in vivo using a swine model. CS-guided balloon-RFA was performed under endoscopic retrograde cholangiography guidance at target temperatures of 60 ℃ or 70 ℃, which were maintained for 60 s. We evaluated the technical feasibility, adverse events, and histological effects associated with the procedure. Twelve sites were ablated in seven miniature pigs. The CS-guided balloon-RFA procedure was technically successful in all cases without any hindrance. Mucosal changes could be detected during RFA, and the ablation area was identified on CS. Necropsy was performed in four pigs on the same day as the procedure: the tissue samples showed coagulative necrosis, and the entire internal circumference of the bile duct was uniformly ablated. The mean lengths of the ablation area in the samples ablated at 60 °C and 70 °C were 20.64 and 22.18 mm, respectively, while the mean depths were 3.46 and 5.07 mm, respectively. The other three pigs were reared and euthanized and autopsied 35 days after the procedure. The site to be ablated had replaced the granulation tissue and fibrotic changes. No adverse events were observed in any case. CS-guided balloon-RFA appears to be a promising option for treating biliary strictures. This preliminary study could pave the way for the evaluation of this procedure in future human clinical trials.

scholarly journals Darkfield orthogonal polarized spectral imaging for studying endovascular laser-tissue interactions in vivo-a preliminary study

2005 ◽  
Vol 13 (3) ◽  
pp. 702 ◽  
Author(s):  
Michal Heger ◽  
Johan F. Beek ◽  
Karin Stenback ◽  
Dirk J. Faber ◽  
Martin J.C. van Gemert ◽  
...  
Keyword(s):  
Spectral Imaging ◽  
Tissue Interactions ◽  
Preliminary Study

Preliminary study of in vivo autofluorescence of nasopharyngeal carcinoma and normal tissue

2000 ◽  
Vol 26 (5) ◽  
pp. 432-440 ◽  
Author(s):  
Jianan Y. Qu ◽  
Po Wing ◽  
Zhijian Huang ◽  
Dora Kwong ◽  
Jonathan Sham ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Normal Tissue ◽  
Preliminary Study
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