Magnetic resonance fingerprinting using echo-planar imaging: Joint quantification of T1 and T2∗ relaxation times

2016 ◽  
Vol 78 (5) ◽  
pp. 1724-1733 ◽  
Author(s):  
Benedikt Rieger ◽  
Fabian Zimmer ◽  
Jascha Zapp ◽  
Sebastian Weingärtner ◽  
Lothar R. Schad
Keyword(s):  
Magnetic Resonance ◽  
Relaxation Times ◽  
Echo Planar Imaging ◽  
Planar Imaging ◽  
T2 Relaxation ◽  
T1 And T2 ◽  
Echo Planar

scholarly journals Magnetic Resonance Fingerprinting with Combined Gradient- and Spin-echo Echo-planar Imaging: Simultaneous Estimation of T1, T2 and T2* with integrated-B1 Correction

2019 ◽  
Author(s):  
Mahdi Khajehim ◽  
Thomas Christen ◽  
J. Jean Chen
Keyword(s):  
Magnetic Resonance ◽  
Spin Echo ◽  
Echo Planar Imaging ◽  
Simultaneous Estimation ◽  
Single Shot ◽  
Planar Imaging ◽  
Reconstruction Process ◽  
Data Segment ◽  
T1 And T2 ◽  
Echo Planar

AbstractPurposeTo introduce a novel magnetic-resonance fingerprinting (MRF) framework with single-shot echo-planar imaging (EPI) readout to simultaneously estimate tissue T2, T1 and T2*, and integrate B1 correction.MethodsSpin-echo EPI is combined with gradient-echo EPI to achieve T2 estimation as well as T1 and T2* quantification. In the dictionary matching step, the GE-EPI data segment provides estimates of tissue T1 and T2* with additional B1 information, which are then incorporated into the T2-matching step that uses the SE-EPI data segment. In this way, biases in T2 and T2* estimates do not affect each other.ResultsAn excellent correspondence was found between our T1, T2, and T2* estimates and results obtained from standard approaches in both phantom and human scans. In the phantom scan, a linear relationship with R2>0.96 was found for all parameter estimates. The maximum error in the T2 estimate was found to be below 6%. In the in-vivo scan, similar contrast was noted between MRF and standard approaches, and values found in a small region of interest (ROI) located in the grey matter (GM) were in line with previous measurements (T2MRF=88±7ms vs T2Ref=89±11ms, T1MRF=1153±154ms vs T1Ref=1122±52ms, T2*MRF=56±4ms vs T2*Ref=53±3ms).ConclusionAdding a spin echo data segment to EPI based MRF allows accurate and robust measurements of T2, T1 and T2* relaxation times. This MRF framework is easier to implement than spiral-based MRF. It doesn’t suffer from undersampling artifacts and seems to require a smaller dictionary size that can fasten the reconstruction process.

Evaluation of Relaxation Time Measurements by Magnetic Resonance Imaging

1987 ◽  
Vol 28 (3) ◽  
pp. 345-351 ◽  
Author(s):  
L. Kjær ◽  
C. Thomsen ◽  
O. Henriksen ◽  
P. Ring ◽  
M. Stubgaard ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Relaxation Time ◽  
Magnetic Resonance ◽  
Diffusion Processes ◽  
Relaxation Times ◽  
Gradient Field ◽  
Maximum Deviation ◽  
Resonance Imaging ◽  
T2 Relaxation ◽  
T1 And T2

Several circumstances may explain the great variation in reported proton T1 and T2 relaxation times usually seen. This study was designed to evaluate the accuracy of relaxation time measurements by magnetic resonance imaging (MRI) operating at 1.5 tesla. Using a phantom of nine boxes with different concentrations of CuSO4 and correlating the calculated T1 and T2 values with reference values obtained by two spectrometers (corrected to MRI-proton frequency=64 MHz) we found a maximum deviation of about 10 per cent. Measurements performed on a large water phantom in order to evaluate the homogeneity in the imaging plane showed a variation of less than 10 per cent within 10 cm from the centre of the magnet in all three imaging planes. Changing the gradient field strength apparently had no influence on the T2 values recorded. Consequently diffusion processes seem without significance. It is concluded that proton T1 and T2 relaxation times covering the majority of the biologic range can be measured by MRI with an overall accuracy of 5 to 10 per cent. Quality control studies along the lines indicated in this study are recommended.

Reliability of 2D single-shot, 2D multi-shot, and 3D echo planar imaging sequences in functional magnetic resonance imaging (fMRI)

NeuroImage ◽  
2000 ◽  
Vol 11 (5) ◽  
pp. S557
Author(s):  
Karsten Specht ◽  
Stephan G. Erberich ◽  
Klaus Willmes ◽  
Stefan Kemeny ◽  
Wolfgang Reith
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Echo Planar Imaging ◽  
Single Shot ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Planar Imaging ◽  
3D Echo ◽  
Echo Planar

scholarly journals Interleaved echo-planar imaging for fast multiplanar magnetic resonance temperature imaging of ultrasound thermal ablation therapy

2004 ◽  
Vol 20 (4) ◽  
pp. 706-714 ◽  
Author(s):  
R. Jason Stafford ◽  
Roger E. Price DVM ◽  
Chris J. Diederich ◽  
Marko Kangasniemi ◽  
Lars E. Olsson ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Thermal Ablation ◽  
Echo Planar Imaging ◽  
Planar Imaging ◽  
Temperature Imaging ◽  
Ablation Therapy ◽  
Thermal Ablation Therapy ◽  
Magnetic Resonance Temperature Imaging ◽  
Echo Planar

scholarly journals Reliability of magnetic resonance elastography using multislice two-dimensional spin-echo echo-planar imaging (SE-EPI) and three-dimensional inversion reconstruction for assessing renal stiffness

2014 ◽  
Vol 42 (3) ◽  
pp. 844-850 ◽  
Author(s):  
Gavin Low ◽  
Nicola E. Owen ◽  
Ilse Joubert ◽  
Andrew J. Patterson ◽  
Martin J. Graves ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Spin Echo ◽  
Three Dimensional ◽  
Echo Planar Imaging ◽  
Magnetic Resonance Elastography ◽  
Two Dimensional ◽  
Planar Imaging ◽  
Echo Planar

Accelerated magnetic resonance diffusion tensor imaging of the median nerve using simultaneous multi-slice echo planar imaging with blipped CAIPIRINHA

2015 ◽  
Vol 26 (6) ◽  
pp. 1921-1928 ◽  
Author(s):  
Lukas Filli ◽  
Marco Piccirelli ◽  
David Kenkel ◽  
Andreas Boss ◽  
Andrei Manoliu ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Magnetic Resonance ◽  
Median Nerve ◽  
Diffusion Tensor ◽  
Echo Planar Imaging ◽  
Planar Imaging ◽  
Echo Planar

Echo-planar imaging: magnetic resonance imaging in a fraction of a second

Science ◽  
1991 ◽  
Vol 254 (5028) ◽  
pp. 43-50 ◽  
Author(s):  
M. Stehling ◽  
R Turner ◽  
P Mansfield
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Echo Planar Imaging ◽  
Resonance Imaging ◽  
Planar Imaging ◽  
Echo Planar

scholarly journals Characterization of Experimental Ischemic Brain Edema Utilizing Proton Nuclear Magnetic Resonance Imaging

1986 ◽  
Vol 6 (2) ◽  
pp. 212-221 ◽  
Author(s):  
Hiroyuki Kato ◽  
Kyuya Kogure ◽  
Hitoshi Ohtomo ◽  
Masahiro Izumiyama ◽  
Muneshige Tobita ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Water Content ◽  
Relaxation Times ◽  
Nmr Imaging ◽  
Tissue Water Content ◽  
T2 Relaxation ◽  
Tissue Water ◽  
T1 And T2 ◽  
Nuclear Magnetic

Correlations between T1 and T2 relaxation times and water and electrolyte content in the normal and ischemic rat and gerbil brains were studied by means of both nuclear magnetic resonance (NMR) spectroscopic and imaging methods. In the spectroscopic experiment on excised rat brains, T1 was linearly dependent on tissue water content and T2 was prolonged in edematous tissue to a greater extent than expected by an increase in water content, showing that T2 possesses a greater sensitivity for edema identification and localization. Changes in Na+ and K+ content of the tissue mattered little in the prolongation of relaxation times. Serial NMR imaging of gerbil brains insulted with permanent hemispheric ischemia offered early lesion detection in T1- and especially T2-weighted images (detection as soon as 30 min after insult). The progressive nature of lesions was also imaged. Calculated T1 and T2 relaxation times in regions of interest correlated excellently with tissue water content ( r = 0.892 and 0.744 for T1 and T2, respectively). As a result, detection of cerebral ischemia utilizing NMR imaging was strongly dependent on a change in tissue water content. The different nature of T1 and T2 relaxation times was also observed.

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