Advances in the quality control of fenugreek seeds using chromatographic, spectroscopic and DNA‐based techniques: A comprehensive review

Chrysanthemum indicum L. (C. indicum L.), a member of the Compositae family, is a perennial plant that has been used as a traditional medicine for more than 2000 years in China and is widely used for the treatment of Pemphigus, swelling, pain, and scrofula. To date, more than 190 chemical constituents have been isolated and identified from this plant, including flavonoids, terpenoids, phenylpropanoids, and phenolic acids. Numerous modern studies have shown that extracts or monomeric compounds from C. indicum L. have several pharmacological activities, such as anti-inflammatory anti-oxidation, antipathogenic microorganism, anticancer, immune regulation, and hepatoprotective effects. However, resource availability, the research on the mechanism, and quality control are still insufficient, which deserves further efforts. In this paper, the advances in botany, phytochemistry, and pharmacology of C. indicum L were reviewed. We hope that this review can provide important information for traditional Chinese medicine, phytochemistry, synthetic and medicinal chemistry researchers for making full use of C. indicum L. resource.

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Authentication and Quality Control Determination of Maple Syrup: A Comprehensive Review

Journal of Food Composition and Analysis ◽

10.1016/j.jfca.2021.103901 ◽

2021 ◽

pp. 103901

Author(s):

Haidy A. Gad ◽

Mohamed Fawzy Ramadan ◽

Mohamed A. Farag

Keyword(s):

Quality Control ◽

Comprehensive Review ◽

Maple Syrup

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Next-Generation Sequencing (NGS) in COVID-19: A Tool for SARS-CoV-2 Diagnosis, Monitoring New Strains and Phylodynamic Modeling in Molecular Epidemiology

Current Issues in Molecular Biology ◽

10.3390/cimb43020061 ◽

2021 ◽

Vol 43 (2) ◽

pp. 845-867

Author(s):

Goldin John ◽

Nikhil Shri Sahajpal ◽

Ashis K. Mondal ◽

Sudha Ananth ◽

Colin Williams ◽

...

Keyword(s):

Quality Control ◽

Next Generation Sequencing ◽

Real World ◽

Next Generation ◽

Comprehensive Review ◽

Current Testing ◽

Phylogenetic Evolution ◽

Next Generation Sequencing Ngs ◽

Ngs Data ◽

Generation Sequencing

This review discusses the current testing methodologies for COVID-19 diagnosis and explores next-generation sequencing (NGS) technology for the detection of SARS-CoV-2 and monitoring phylogenetic evolution in the current COVID-19 pandemic. The review addresses the development, fundamentals, assay quality control and bioinformatics processing of the NGS data. This article provides a comprehensive review of the obstacles and opportunities facing the application of NGS technologies for the diagnosis, surveillance, and study of SARS-CoV-2 and other infectious diseases. Further, we have contemplated the opportunities and challenges inherent in the adoption of NGS technology as a diagnostic test with real-world examples of its utility in the fight against COVID-19.

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Autophagy and Autophagy-Related Diseases: A Review

International Journal of Molecular Sciences ◽

10.3390/ijms21238974 ◽

2020 ◽

Vol 21 (23) ◽

pp. 8974

Author(s):

Tadashi Ichimiya ◽

Tsukasa Yamakawa ◽

Takehiro Hirano ◽

Yoshihiro Yokoyama ◽

Yuki Hayashi ◽

...

Keyword(s):

Quality Control ◽

Cell Differentiation ◽

Physiological Function ◽

Degradation Products ◽

Starvation Response ◽

Comprehensive Review ◽

Selective Autophagy ◽

Related Disease

Autophagy refers to the process involving the decomposition of intracellular components via lysosomes. Autophagy plays an important role in maintaining and regulating cell homeostasis by degrading intracellular components and providing degradation products to cells. In vivo, autophagy has been shown to be involved in the starvation response, intracellular quality control, early development, and cell differentiation. Recent studies have revealed that autophagy dysfunction is implicated in neurodegenerative diseases and tumorigenesis. In addition to the discovery of certain disease-causing autophagy-related mutations and elucidation of the pathogenesis of conditions resulting from the abnormal degradation of selective autophagy substrates, the activation of autophagy is essential for prolonging life and suppressing aging. This article provides a comprehensive review of the role of autophagy in health, physiological function, and autophagy-related disease.

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