fenugreek seeds
Recently Published Documents


TOTAL DOCUMENTS

320
(FIVE YEARS 116)

H-INDEX

28
(FIVE YEARS 3)

2022 ◽  
Vol 3 (1) ◽  
pp. 01-08
Author(s):  
Azab Elsayed Azab ◽  
Mohamed Omar Albasha ◽  
Manal Abuelkasem Elnaif

The present study aimed to investigate the ameliorative effects of fenugreek seeds and curcumin on hematotoxicity induced by nicotine in male albino rats. 30 male F-344/NHsd Fischer rats, weighing from 180 to 200g were used in the present study. The animals were divided into five groups (6 rats for each); Group I (control group), Group II (nicotine treated group), Group III (nicotine/fenugreek seeds co-administered), Group IV (nicotine/curcumin co-administered), and Group V (nicotine/curcumin& fenugreek seeds co-administered). At the end of the experimentation and 24 hours after the last dose, all animals were anaesthetized with ether and blood samples were collected by heart puncture. The samples were collected in clean dry tubes containing the anticoagulant substance EDTA and used for the hematological studies. The results showed that the animals treated with nicotine for 4 weeks showed a significant decrease in RBCs count, hemoglobin concentration, hematocrit value, MCH, MCHC, and platelets count, and increased MCV and WBCs count as compared to the control group. Co-administration of nicotine with fenugreek and/or curcumin caused improvement in all hematological parameters when compared with nicotine group. It can be concluded that nicotine had a strong effect on the hematological parameters. The ingestion of fenugreek and/or curcumin prevent the hematoxicity induced by nicotine. The current study suggests that fenugreek and curcumin may be useful in combating free radical-induced hematotoxicity induced by nicotine.


2022 ◽  
pp. 399-410
Author(s):  
Ram B. Singh ◽  
Manal M.A. Smail ◽  
Richa H. Rai ◽  
Anuj Maheshwari ◽  
Narsingh Verma ◽  
...  

2021 ◽  
Vol 5 (01) ◽  
pp. 36-44
Author(s):  
Babita Adhikari ◽  
Shonu Rai

Phytate and tannin are more pronounced antinutrients limiting the nutritional quality of fenugreek. The impact of roasting (130±5°C for 7 minutes), soaking (12 hrs. at room temperature) and germination (72 hrs. at 25°C) on bioactive compounds (polyphenol and antioxidant activity), nutritional and anti-nutritional compounds (phytate and tannin) in Fenugreek were studied. Experimental data were analyzed using the software GenStat 12th Edition. Protein increased significantly (p<0.05) during roasting, soaking, and germination whereas fat decreased significantly. Iron and calcium increased during roasting whereas decreased during soaking and germination. Maximum reduction of phytate (54.55%) and tannin (66.73%) were found when fenugreek seeds were germinated (72 hours). The reduction percentage of antinutrients by soaking (12 hours) and roasting (130±5⁰C for 7 mins) was found to be a lesser effective method compared to germination. All the treatments had a significant (p<0.05) impact on their bioactive components. Phenolic content increased significantly (p<0.05) during roasting, soaking, and germination. Antioxidant activity (IC50=1.28mg dm/ml) was found to be high in the germinated samples as compared to raw, roasted, and soaked samples. Hence, Germination of fenugreek seeds for 72 hours is concluded as the most effective and promising method for the reduction of antinutrients and increasing the nutritional components, phytochemicals, and antioxidant properties.


Author(s):  
Natsuko Urushihara ◽  
Tadahiko Hirai ◽  
Akansha Dager ◽  
Yuta Nakamura ◽  
Yuma Nishi ◽  
...  
Keyword(s):  

Author(s):  
Adikeshavan Thilagavathy ◽  
Kavitha G Singh ◽  
Melantha Janet Lobo ◽  
Mayuri Mayuri

Obesity poses a major threat to global health, challenging the prevention of chronic diseases and health across the world. As synthetic medicines have their side effects, lately, there has been an inclination towards herbal remedies. The present study was conducted to evaluate the individual and syngeristic effect of Linum usitatissimum (flax seeds), Trigonella foenum graecum (fenugreek seeds) and Nigella sativa (black seeds) on obesity. In-vivo studies were performed in Drosophila as many tissues and organs related to obesity and its associated disorders are analogous in Drosophila and humans. Obesity was induced by supplementing lipid and high concentration of glucose in the media. The effect of the seeds on obesity was studied by quantitative estimation of lipid content and carbohydrate content in the larvae grown in different media preparations and also by assessment of physical activity of the flies. The study revealed the efficient ability of the seeds to reduce obesity, synergistically as well as individually proving it to be a potential strategy to combat the obesity naturally.


Author(s):  
PRYTULSKA Nataliia ◽  
MOTUZKA Yuliia ◽  
KOSHELNYK Anna

Background. Today, diabetes is one of the most common diseases with a steady upward trend. In particular in Ukraine it ranks 2nd among endocrine diseases in the number of patients. The annual growth of such patients averages 9.8–11 %. In the treatment of endocrine diseases, dietary nutrition aimed at normalizing metabolismis of great importance. It is recommended to add to the diet special, func­tionally-oriented foods based on biologically valuable raw materials. The aim of the workis to determine the physiological efficiency of drinks from fenugreek seeds. Materials and methods. The physiological effects of fenugreek seed drinks were determined from clinical trials involving 54 patients with type II diabetes and 40 patients diagnosed with pre-diabetes. Two groups of 32 patients who did not consume the product were also selected. Biochemical methods were used to assess the effect of the product on the correction of condition of patients according to the indicators of the general condition of patients, the indicator of the level of glucose and cholesterol in the blood.The assessment of physical and psycho-emotional states was conducted by a survey. Drink is a plant-based milk analogue from the fenugreek seeds is presented in a ready-to-drink form.Depending on the disease and the condition of the body, participants in clinical trials drank the developed drink daily at 200–400 cm3/day (1–2 times a day at 200 cm3) for 30–60 days together with an individually prescribed treatment package. Results. It was found that patients who consumed a drink of fenugreek seeds in addition to the main diet had a faster normalization of blood glucose levels, more pronounced improvement in physical condition, as well as a reduction in the overall duration of treatment than patients in the control group. There was an improvement in lipid metabolism in patients of both study groups who drank a plant-based milk analogue from fenugreek seeds, and patients have noted that consumption of the developed drink helped to improve the condition of the gastrointestinal tract.This can be explained by the large number of galactomannans in the fenugreek seeds, which promote the secretion of mucous substances during the production of the drink. Conclusion. The new plant-based milk analogue from fenugreek seeds helps to normalize blood sugar and cholesterol levels, and therefore can be recommended for use in dietary and therapeutic diets of people with diabetes and atherosclerosis during treatment and recovery. Taking into accountthe properties of fenugreek seeds, the developed product can be recommended to protect the organs of the gastrointestinal tract in these diseases and in general to normalize metabolism.


2021 ◽  
Vol 13 (3) ◽  
pp. 1083-1093
Author(s):  
Vikas Kumar ◽  
Vivek Akhouri ◽  
Sushil Kumar Singh ◽  
Arun Kumar

The prime objective of the present study was to establish fenugreek (Trigonella foenum-graecum L.) seeds extract as an antidote against arsenic induced hepato-renal toxicity in rats. The male Charles Foster rats (weighing 160-180 g) were selected to make arsenic intoxicated model. The arsenic treated group of rats were orally treated with sodium arsenite at the dose of 8 mg/kg body weight/day for 90 days. Thereafter, the arsenic pretreated rats were further administered with fenugreek ethanolic seeds extract at the dose of 250 mg/kg body weight/day for 90 days.  After the completion of the treatment, animals of all the groups were sacrificed for the biochemical and histopathological estimation. The arsenic treated rats showed significant (p < 0.0001) alterations at the various hepatic and renal biomarker parameters and at serum MDA levels in comparison to the control rats.  Significant (p < 0.0001) arsenic accumulation was also observed in the blood, liver and kidney tissues of the arsenic treated rats. However, after the administration with fenugreek seeds extract, significant (p < 0.0001) restoration was observed in the liver and kidney biomarker parameters and at haematological variables. Fenugreek seeds extract administration also significantly (p < 0.0001) reduced the serum MDA levels and arsenic concentration levels in blood, liver and kidney tissues, along with considerable restorations at the cellular architecture of liver and kidney tissues. The study concluded that fenugreek seeds possessed potential hepato-renal ameliorative effect against sodium arsenite induced toxicity in rats, and can be used for its therapeutic value against arsenic poisoning.


Sign in / Sign up

Export Citation Format

Share Document