scholarly journals Preparation of silk fibroin-poly(ethylene glycol) conjugate films through click chemistry

2011 ◽  
Vol 60 (12) ◽  
pp. 1737-1744 ◽  
Author(s):  
Sandra Sampaio ◽  
Teresa M. R. Miranda ◽  
Jorge G. Santos ◽  
Graça M. B. Soares
2014 ◽  
Vol 5 (13) ◽  
pp. 4002-4008 ◽  
Author(s):  
Hong Du ◽  
Guangyu Zha ◽  
Lilong Gao ◽  
Huan Wang ◽  
Xiaodong Li ◽  
...  

Novel biodegradable antimicrobial hydrogels, which are promising for use as biomaterials, were prepared facilely via a thiol–ene “click” reaction under human physiological conditions using multifunctional poly(ethylene glycol) (PEG) derivatives as precursors.


2018 ◽  
Vol 6 (30) ◽  
pp. 4929-4936 ◽  
Author(s):  
Faraz Jivan ◽  
Natalia Fabela ◽  
Zachary Davis ◽  
Daniel L. Alge

A two-step, click chemistry approach to create user-defined hydrogels consisting of poly(ethylene glycol) and bioactive peptides without the use of multi-arm precursors for tissue engineering.


2017 ◽  
Vol 50 (5) ◽  
pp. 1824-1831 ◽  
Author(s):  
Tugrul Cem Bicak ◽  
Mindaugas Gicevičius ◽  
Tugba Ceren Gokoglan ◽  
Gorkem Yilmaz ◽  
Arunas Ramanavicius ◽  
...  

2016 ◽  
Vol 4 (26) ◽  
pp. 4574-4584 ◽  
Author(s):  
S. Ryu ◽  
H. H. Kim ◽  
Y. H. Park ◽  
C.-C. Lin ◽  
I. C. Um ◽  
...  

Hydrogel formation by more than two cross-linking mechanisms is preferred for the sophisticated manipulation of hydrogel properties.


2020 ◽  
Vol 8 (16) ◽  
pp. 4626-4637 ◽  
Author(s):  
Anne Nguyen ◽  
Hidenori Ando ◽  
Roland Böttger ◽  
K. K. DurgaRao Viswanadham ◽  
Elham Rouhollahi ◽  
...  

Click chemistry was used to study the effect of varied PEG molecular weights on the self-assembly of PEG-gambogic acid (GA) conjugates into nanoparticles.


2015 ◽  
Vol 27 (1) ◽  
pp. 22-39 ◽  
Author(s):  
Karolyn Barker ◽  
Shiva K. Rastogi ◽  
Jose Dominguez ◽  
Travis Cantu ◽  
William Brittain ◽  
...  

Nanomedicine ◽  
2021 ◽  
Author(s):  
Xueping Liu ◽  
Hong Luo ◽  
Longxing Niu ◽  
Yanfei Feng ◽  
Peng Pan ◽  
...  

Aim: To obtain a gene carrier that can effectively deliver loaded therapeutic genes to tumor cells, avoid toxic effects on normal cells and reduce nonspecific adsorption of plasma proteins. Methods: The conjugate of poly(ethylene glycol) (PEG) and MMP2SSP (PEG-MMP2SSP) was covalently coupled to cationized Antheraea pernyi silk fibroin (CASF) through disulfide bond exchange reaction to obtain a PEG-MMP2SSP-modified CASF (CASFMP). Results: The PEG chains were effectively cleaved from the CASFMP by MMP2. CASFMP/pDNA complexes inhibited human fibrosarcoma cell proliferation, and its cytotoxicity to human normal embryonic kidney cells was significantly lower than that of poly(ethylenimine)/pDNA after coculturing with cells for 24 h. Conclusion: CASFMP is a promising compound for use in gene therapy.


2008 ◽  
Vol 3 (3) ◽  
pp. 034115 ◽  
Author(s):  
HaeYong Kweon ◽  
Joo-hong Yeo ◽  
Kwang-gill Lee ◽  
Hyun Chul Lee ◽  
Hee Sam Na ◽  
...  

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