Effect of Nigella sativa oil extract on cardiometabolic risk factors in type 2 diabetes: A randomized, double‐blind , placebo‐controlled clinical trial

2021 ◽  
Author(s):  
Saeid Hadi ◽  
Reza Daryabeygi‐Khotbehsara ◽  
Parvin Mirmiran ◽  
Jenna McVicar ◽  
Vahid Hadi ◽  
...  
Author(s):  
Joana Furtado de Figueiredo Neta ◽  
Vivian Saraiva Veras ◽  
Danilo Ferreira de Sousa ◽  
Maria da Conceição dos Santos Oliveira Cunha ◽  
Maria Veraci Oliveira Queiroz ◽  
...  

2013 ◽  
Vol 2 (2) ◽  
pp. 1 ◽  
Author(s):  
Dieudonne Kuate ◽  
Anne Pascale Nouemsi Kengne ◽  
William Dakam ◽  
Blanche Cunegonde Omgba Etoundi ◽  
Ghislain Djiokeng Paka ◽  
...  

This work evaluated the effect of <em>Dichrostachys glomerata </em>on the improvement of antioxidant biomarkers in obesity and type 2 diabetes participants, in an eight-week randomized, double-blind, placebo-controlled design study. The active (400 mg) or placebo formulation were administered twice daily throughout the study period to two normoglycemic and two diabetic obese random groups. Plasma levels of a total of 8 biochemical parameters were taken at the baseline and after 4 and 8 weeks of treatment. No differences in urate variation were observed while the plasma phenolic content as well as the reduced glutathione level, ascorbate concentration, FRAP value and enzymatic antioxidant activities significantly increased with a concomitant reduction of MDA after 8 weeks compared to placebo (P &lt; 0.01). On the contrary to urate and ascorbate, plasma polyphenol content correlated well with FRAP level in both treated groups indicating that phenolics from the spice greatly contributed to the antioxidant activity.


2020 ◽  
Vol 34 (10) ◽  
pp. 2706-2711
Author(s):  
Akram Kooshki ◽  
Tahereh Tofighiyan ◽  
Neda Rastgoo ◽  
Mohammad Hassan Rakhshani ◽  
Mohammad Miri

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