Determination of cellular redox status by stable isotope dilution liquid chromatography/mass spectrometry analysis of glutathione and glutathione disulfide

2008 ◽  
Vol 22 (4) ◽  
pp. 432-440 ◽  
Author(s):  
Peijuan Zhu ◽  
Tomoyuki Oe ◽  
Ian A. Blair
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Redox Status ◽  
Mass Spectrometry Analysis ◽  
Glutathione Disulfide ◽  
Liquid Chromatography Mass Spectrometry ◽  
Cellular Redox ◽  
Spectrometry Analysis ◽  
Stable Isotope Dilution

scholarly journals Sample Preparation and Liquid Chromatography Mass Spectrometry Analysis of Alkylphenolic Compounds and Steroid Sex Hormones in Sediments

2002 ◽  
Vol 2 ◽  
pp. 1610-1616 ◽  
Author(s):  
Mira Petrovia ◽  
Damia Barcela
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Sex Hormones ◽  
Degradation Products ◽  
Mass Spectrometry Analysis ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Analysis ◽  
Chromatography Mass Spectrometry ◽  
Steroid Sex Hormones

A new methodology, based on the use of accelerated solvent extraction (ASE) and highly selective cleanup using restricted access material (RAM) on-line coupled with liquid chromatography–mass spectrometry (LC–MS), is presented for the simultaneous and unequivocal determination of alkylphenol ethoxylates (APEOs), their degradation products and halogenated derivatives, and steroid sex hormones in sediment samples. Using the integrated RAM–LC–MS system, the simultaneous determination of alkylphenolic compounds and sex hormones was achieved, yielding recoveries higher than 60% and producing low MS background noise.

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