Mass spectrometry and ion mobility study of poly(ethylene glycol)‐based polyurethane oligomers

2020 ◽  
Vol 34 (S2) ◽  
Author(s):  
Rachel A. Harris ◽  
Jaqueline A. Picache ◽  
Ian D. Tomlinson ◽  
Emanuel Zlibut ◽  
Berkley M. Ellis ◽  
...  

2002 ◽  
Vol 37 (7) ◽  
pp. 699-708 ◽  
Author(s):  
K. Norrman ◽  
A. Papra ◽  
F. S. Kamounah ◽  
N. Gadegaard ◽  
N. B. Larsen




2007 ◽  
Vol 21 (7) ◽  
pp. 1214-1220 ◽  
Author(s):  
Michael J. Bogan ◽  
Elizabeth Patton ◽  
Abneesh Srivastava ◽  
Sue Martin ◽  
David P. Fergenson ◽  
...  


2012 ◽  
Vol 1403 ◽  
Author(s):  
Benjamin F. Pierce ◽  
Axel T. Neffe ◽  
Andreas Lendlein

ABSTRACTGelatin was functionalized with glycidyl methacrylate and photocrosslinked in the presence of poly(ethylene glycol) dimethacrylate (PEGDMA) or poly(ethylene glycol) monomethacrylate (PEGMA) to create a biopolymer-based system with tailorable properties. These co-networks were hydrolyzed using 6 M HCl and the degradation products were analyzed and identified using matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry. This technique successfully identified gelatin-derived peptides such as FLPEPPE, SFLPEPPE, and SFLPEPPEE as well as an accompanying PEG-g-poly(methacrylic acid) component. No oligo- or polymethacrylates were monitored at any molecular weight range above m/z = 500, which indicated that they possessed lower molecular weights. An in vitro hydrolytic degradation experiment performed in pH 7.4 PBS buffer solution at 37 °C showed that these networks, which were prepared without the addition of a potentially toxic photoinitiator, exhibited mass loss of up to 50 wt% at 6 weeks of incubation time. These results provide valuable insight into how these functional gelatin-based co-network biomaterials will perform in a biological setting.



The Analyst ◽  
2000 ◽  
Vol 125 (4) ◽  
pp. 605-608 ◽  
Author(s):  
Gwyn A. Lord ◽  
Hong Cai ◽  
Jin Li Luo ◽  
Chang Kee Lim


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