scholarly journals The Role of Nerve Growth Factor in Maintaining Proliferative Capacity, Colony-Forming Efficiency, and the Limbal Stem Cell Phenotype

Stem Cells ◽  
2018 ◽  
Vol 37 (1) ◽  
pp. 139-149 ◽  
Author(s):  
Sai Kolli ◽  
Sanja Bojic ◽  
Ali E. Ghareeb ◽  
Marzena Kurzawa-Akanbi ◽  
Francisco C. Figueiredo ◽  
...  
Author(s):  
Andrew J. DeCastro ◽  
James DiRenzo

AbstractStem cells belong to a unique class of cells that is collectively responsible for the development and subsequent maintenance of all tissues comprising multicellular organisms. These cells possess unique characteristics that allow them to remain in a pluripotent state, while also continuing to generate differentiated cells. microRNAs, a specialized class of non-coding RNAs, are integral components of the network of pathways that modulates this combination of abilities. This review highlights recent discoveries about the roles miRNAs play in governing stem cell phenotype, and discusses the potential therapeutic utility that miRNAs may have in the treatment of multiple diseases. Additionally, it addresses a novel mode of regulation of stem cell phenotype through lincRNA-mediated modulation of select miRNAs, and the role of secreted, stem cell-derived miRNAs in exerting a paracrine influence on surrounding non-stem cells.


2010 ◽  
Vol 51 (2) ◽  
pp. 765 ◽  
Author(s):  
Ewa Anna Meyer-Blazejewska ◽  
Friedrich E. Kruse ◽  
Katrin Bitterer ◽  
Christian Meyer ◽  
Carmen Hofmann-Rummelt ◽  
...  

Oncotarget ◽  
2017 ◽  
Vol 8 (29) ◽  
pp. 47454-47473 ◽  
Author(s):  
Yuh-Jin Liang ◽  
Chen-Yu Wang ◽  
I-An Wang ◽  
Yi-Wen Chen ◽  
Li-Tzu Li ◽  
...  

Cytotherapy ◽  
2014 ◽  
Vol 16 (4) ◽  
pp. S92
Author(s):  
A. Popova ◽  
A. Ulyanov ◽  
O. Fechin ◽  
I. Valamina ◽  
O. Shilovskih

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