One‐pot synthesis of ICG&Cur@ZIF‐8 nanocomposites with pH‐controlled drug delivery and good photothermal performance

2021 ◽  
Author(s):  
Yifei Su ◽  
Weishu Ni ◽  
Haiyan Zhang ◽  
Ke Jiang ◽  
Feng Wen
Keyword(s):  
Drug Delivery ◽  
Controlled Drug Delivery ◽  
One Pot ◽  
One Pot Synthesis ◽  
Ph Controlled

Facile One‐Pot Synthesis of Magnetic Targeted Polymers for Drug Delivery and Study on Thermal Decomposition Kinetics

2021 ◽  
Vol 6 (6) ◽  
pp. 1191-1198
Author(s):  
Zhen Shi ◽  
Yazhen Wang ◽  
Yu Sun ◽  
Xueying Wu ◽  
Tianyuan Xiao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Thermal Decomposition ◽  
Decomposition Kinetics ◽  
Thermal Decomposition Kinetics ◽  
One Pot ◽  
One Pot Synthesis

One-pot synthesis of hierarchical-pore metal–organic frameworks for drug delivery and fluorescent imaging

CrystEngComm ◽  
2018 ◽  
Vol 20 (8) ◽  
pp. 1087-1093 ◽  
Author(s):  
Xuechuan Gao ◽  
Yuewu Wang ◽  
Guanfeng Ji ◽  
Ruixue Cui ◽  
Zhiliang Liu
Keyword(s):  
Drug Delivery ◽  
Metal Organic Frameworks ◽  
Fluorescent Imaging ◽  
One Pot ◽  
One Pot Synthesis ◽  
Drug Molecules ◽  
Metal Organic ◽  
Hierarchical Pore

A one-pot process has been developed for the synthesis of hierarchical-pore metal–organic frameworks, aimed at loading large and small drug molecules simultaneously.

One-pot synthesis of camptothecin-loaded glutathione-responsive PEGlyation nanogels as novel antitumor therapeutics

2019 ◽  
Vol 9 (7) ◽  
pp. 757-763 ◽  
Author(s):  
Xiao Duan ◽  
Xue Yang ◽  
Chunlei Dai ◽  
Tong Tong ◽  
Congxiu Miao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Cell Viability ◽  
Small Molecules ◽  
A549 Cells ◽  
One Pot ◽  
Anticancer Efficacy ◽  
Anticancer Drug Delivery ◽  
One Pot Synthesis ◽  
Correct Size

PEGlyation nanogels have shown potential in cancer therapy due to their outstanding biodegradability and biocompatibility. In this study, glutathione (GSH)-responsive PEGlyation nanogels were loaded with camptothecin (CPT) (CPT@A2B5-PEG) by one-pot synthesis based on the monomers of disulfide-based diacrylate (A2) and N-(2-aminoethyl) ethane-1,2-diamine (B5). The nanogels with responsive cross-linked networks were degraded into small molecules according to their GSH-sensitivity. The nanogels were of the correct size as measured by TEM and DLS, and uptake into A549 cells was observed within 6 h. Cell viability assays showed that CPT@A2B5-PEG produced similar anticancer efficacy to free CPT. The GSH-responsive CPT-loaded PEGlyation nanogels produced by one-pot synthesis are therefore promising platforms for anticancer drug delivery.

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