Parallel Oscillations of Intracellular Calcium Activity and Mitochondrial Membrane Potential in Mouse Pancreatic B-Cells

2000 ◽  
Vol 267 (1) ◽  
pp. 179-183 ◽  
Author(s):  
Peter Krippeit-Drews ◽  
Martina Düfer ◽  
Gisela Drews
Keyword(s):  
Membrane Potential ◽  
B Cells ◽  
Intracellular Calcium ◽  
Mitochondrial Membrane Potential ◽  
Mitochondrial Membrane ◽  
Calcium Activity ◽  
Pancreatic B Cells

Oxidative stress in cells exposed to low levels of ionizing radiation

2001 ◽  
Vol 29 (2) ◽  
pp. 350-353 ◽  
Author(s):  
F. M. Lyng ◽  
C. B. Seymour ◽  
C. Mothersill
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Membrane Potential ◽  
Intracellular Calcium ◽  
Mitochondrial Membrane Potential ◽  
Mitochondrial Membrane ◽  
Reactive Oxygen ◽  
Human Keratinocytes ◽  
Oxygen Species ◽  
Significant Difference

The ability of medium from γ-irradiated cells to induce early events in the apoptotic cascade, such as the mobilization of intracellular calcium, loss of mitochondrial membrane potential and increased levels of reactive oxygen species, in unirradiated cells was investigated. Medium from irradiated human keratinocytes was harvested and transferred to unirradiated keratinocytes. Intracellular calcium levels, mitochondrial membrane potential and the level of reactive oxygen species were all monitored for a period of 24 h following medium transfer. Rapid calcium fluxes (within 30 s), loss of mitochondrial membrane potential and increases in reactive oxygen species (from 6 h after medium transfer) were observed. There was no significant difference between the effects of medium generated by cells irradiated at 0.5 Gy or 5 Gy. The data suggest that a signal that leads to apoptosis is released from cells undergoing radiation-induced oxidative stress.

scholarly journals Fluctuating vs. Continuous Exposure to H2O2: The Effects on Mitochondrial Membrane Potential, Intracellular Calcium, and NF-κB in Astroglia

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e76383 ◽  
Author(s):  
Aleksandar Bajić ◽  
Mihajlo Spasić ◽  
Pavle R. Andjus ◽  
Danijela Savić ◽  
Ana Parabucki ◽  
...  
Keyword(s):  
Membrane Potential ◽  
Intracellular Calcium ◽  
Mitochondrial Membrane Potential ◽  
Mitochondrial Membrane ◽  
Continuous Exposure
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