IRF-1-Mediated CAS Expression Enhances Interferon-γ-Induced Apoptosis of HT-29 Colon Adenocarcinoma Cells

2001 ◽  
Vol 4 (6) ◽  
pp. 353-358 ◽  
Author(s):  
Ming-Chung Jiang ◽  
Tai-Lang Lin ◽  
Tao-Lin Lee ◽  
Hsin-Tien Huang ◽  
Ching-Liang Lin ◽  
...  
Keyword(s):  
Colon Adenocarcinoma ◽  
Interferon Γ ◽  
Adenocarcinoma Cells ◽  
Induced Apoptosis ◽  
Ht 29 ◽  
Colon Adenocarcinoma Cells

scholarly journals Effect of β-carotene-rich tomato lycopene β-cyclase (tlcy-b) on cell growth inhibition in HT-29 colon adenocarcinoma cells

2008 ◽  
Vol 102 (2) ◽  
pp. 207-214 ◽  
Author(s):  
Paola Palozza ◽  
Diana Bellovino ◽  
Rossella Simone ◽  
Alma Boninsegna ◽  
Francesco Cellini ◽  
...  
Keyword(s):  
Cell Growth ◽  
Growth Inhibition ◽  
Colon Adenocarcinoma ◽  
Human Colon ◽  
Cell Growth Inhibition ◽  
Adenocarcinoma Cells ◽  
Ht 29 ◽  
Colon Adenocarcinoma Cells ◽  
Β Carotene

Lycopene β-cyclase (tlcy-b) tomatoes, obtained by modulating carotenogenesis via genetic engineering, contain a large amount of β-carotene, as clearly visible by their intense orange colour. In the present study we have subjected tlcy-b tomatoes to an in vitro simulated digestion and analysed the effects of digestate on cell proliferation. To this aim we used HT-29 human colon adenocarcinoma cells, grown in monolayers, as a model. Digested tomatoes were diluted (20 ml, 50 ml and 100 ml/l) in culture medium and added to the cells for different incubation times (24 h, 48 h and 72 h). Inhibition of cell growth by tomato digestate was dose-dependent and resulted from an arrest of cell cycle progression at the G0/G1 and G2/M phase and by apoptosis induction. A down-regulation of cyclin D1, Bcl-2 and Bcl-xl expression was observed. We also found that heat treatment of samples before digestion enhanced β-carotene release and therefore cell growth inhibition. To induce with purified β-carotene solubilised in tetrahydrofuran the same cell growth inhibition obtained with the tomato digestate, a higher amount of the carotenoid was necessary, suggesting that β-carotene micellarised during digestion is utilised more efficiently by the cells, but also that other tomato molecules, reasonably made available during digestion, may be present and cooperate with β-carotene in promoting cell growth arrest.

The proliferative response of HT-29 human colon adenocarcinoma cells to bombesin-like peptides

2001 ◽  
Vol 172 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Giuseppe Cassano ◽  
Nicoletta Resta ◽  
Giuseppe Gasparre ◽  
Claudio Lippe ◽  
Ginevra Guanti
Keyword(s):  
Proliferative Response ◽  
Colon Adenocarcinoma ◽  
Human Colon ◽  
Adenocarcinoma Cells ◽  
Ht 29 ◽  
Human Colon Adenocarcinoma ◽  
Colon Adenocarcinoma Cells

Isolation and anticancer effect of brucine in human colon adenocarcinoma cells HT-29

2021 ◽  
Vol 17 (74) ◽  
pp. 367
Author(s):  
Jianping Zhao ◽  
Zhenyu Feng ◽  
Shuang Meng ◽  
Xiaorong Zhou ◽  
Xiaojuan Ma ◽  
...  
Keyword(s):  
Colon Adenocarcinoma ◽  
Human Colon ◽  
Anticancer Effect ◽  
Adenocarcinoma Cells ◽  
Ht 29 ◽  
Human Colon Adenocarcinoma ◽  
Colon Adenocarcinoma Cells

scholarly journals The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells

2003 ◽  
Vol 24 (8) ◽  
pp. 1361-1367 ◽  
Author(s):  
R. Hu ◽  
B. R. Kim ◽  
C. Chen ◽  
V. Hebbar ◽  
A.-N.T. Kong
Keyword(s):  
Signaling Pathways ◽  
Colon Adenocarcinoma ◽  
Apoptotic Signaling ◽  
Adenocarcinoma Cells ◽  
Ht 29 ◽  
Colon Adenocarcinoma Cells

Comparative proteomics analysis of the antitumor effect of CIGB-552 peptide in HT-29 colon adenocarcinoma cells

2015 ◽  
Vol 126 ◽  
pp. 163-171 ◽  
Author(s):  
Teresa Núñez de Villavicencio-Díaz ◽  
Yassel Ramos Gómez ◽  
Brizaida Oliva Argüelles ◽  
Julio R. Fernández Masso ◽  
Arielis Rodríguez-Ulloa ◽  
...  
Keyword(s):  
Antitumor Effect ◽  
Colon Adenocarcinoma ◽  
Comparative Proteomics ◽  
Proteomics Analysis ◽  
Adenocarcinoma Cells ◽  
Ht 29 ◽  
Colon Adenocarcinoma Cells
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