The Binge Eating-Prone/Binge Eating-Resistant Animal Model: A Valuable Tool for Examining Neurobiological Underpinnings of Binge Eating

2020 ◽  
pp. 7-24
Author(s):  
Natasha Fowler ◽  
Nicollette Russell ◽  
Cheryl L. Sisk ◽  
Alexander W. Johnson ◽  
Kelly L. Klump
Keyword(s):  
Animal Model ◽  
Binge Eating ◽  
Resistant Animal

scholarly journals Hypothalamic expression of inflammatory mediators in an animal model of binge eating

2017 ◽  
Vol 320 ◽  
pp. 420-430 ◽  
Author(s):  
Silvia Alboni ◽  
Maria Vittoria Micioni Di Bonaventura ◽  
Cristina Benatti ◽  
Maria Elena Giusepponi ◽  
Nicoletta Brunello ◽  
...  
Keyword(s):  
Animal Model ◽  
Binge Eating ◽  
Inflammatory Mediators

scholarly journals The Disruptive Effects of Estrogen Removal Before Puberty on Risk for Binge Eating in Female Rats

2020 ◽  
Vol 8 (5) ◽  
pp. 839-856 ◽  
Author(s):  
Kelly L. Klump ◽  
Elaine B. Sinclair ◽  
Britny A. Hildebrandt ◽  
Deborah A. Kashy ◽  
Shannon O’Connor ◽  
...  
Keyword(s):  
Animal Model ◽  
Binge Eating ◽  
Brain Development ◽  
Causal Effects ◽  
Female Rats ◽  
Adult Females ◽  
Ovx Rats ◽  
Adolescent Brain Development ◽  
Intact Rats

Recent research suggests that estrogen is protective against binge eating in adult females and that pubertal estrogen may be critical for these effects. Nonetheless, to date, no study has examined the role of pubertal estrogen in adult binge-eating phenotypes in females, potentially because of difficulties experimentally manipulating estrogen in humans to examine causal effects. We used a novel animal model to examine whether estrogen removal before puberty (via prepubertal ovariectomy, or P-OVX) increased rates of binge-eating-prone (BEP) phenotypes in adulthood in female rats. Seventy-seven P-OVX rats and 79 intact rats were followed from prepuberty into adulthood and phenotyped for BEP status in adulthood. Results showed significantly increased rates (~2–8 times higher) of adult BEP phenotypes in P-OVX compared with intact rats. Findings confirm that estrogen removal substantially increases later risk for binge eating in females, potentially by disrupting typical adolescent brain development.

scholarly journals CIAPIN1 gene silencing enhances chemosensitivity in a drug-resistant animal model in vivo

2014 ◽  
Vol 47 (4) ◽  
pp. 273-278 ◽  
Author(s):  
X.M. Wang ◽  
S.J. Gao ◽  
X.F. Guo ◽  
W.J. Sun ◽  
Z.Q. Yan ◽  
...  
Keyword(s):  
Animal Model ◽  
Gene Silencing ◽  
Drug Resistant ◽  
Resistant Animal

Effect of the orexin receptors antagonists in an animal model of binge eating

Appetite ◽  
2011 ◽  
Vol 57 ◽  
pp. S30
Author(s):  
M.V. Micioni Di B ◽  
C. Cifani ◽  
M. Corsi ◽  
D. Montanari ◽  
R. Ciccocioppo ◽  
...  
Keyword(s):  
Animal Model ◽  
Binge Eating ◽  
Orexin Receptors

scholarly journals Motivation for palatable food despite consequences in an animal model of binge eating

2011 ◽  
Vol 44 (3) ◽  
pp. 203-211 ◽  
Author(s):  
Kimberly D. Oswald ◽  
Donna L. Murdaugh ◽  
Vinetra L. King ◽  
Mary M. Boggiano
Keyword(s):  
Animal Model ◽  
Binge Eating ◽  
Palatable Food

The role of palatable food and hunger as trigger factors in an animal model of stress induced binge eating

2003 ◽  
Vol 34 (2) ◽  
pp. 183-197 ◽  
Author(s):  
Mary M. Hagan ◽  
Paula C. Chandler ◽  
Pamela K. Wauford ◽  
Rachel J. Rybak ◽  
Kimberly D. Oswald
Keyword(s):  
Animal Model ◽  
Binge Eating ◽  
Palatable Food ◽  
Trigger Factors

Abstract 1519: Cantrixil targets ovarian cancer stem cells and prevents recurrence in a cisplatin-resistant animal model

2015 ◽  
Author(s):  
Gil G. Mor ◽  
Eydis Lima ◽  
Natalia Sumi ◽  
Mary Pitruzzello ◽  
Yang Yang-Hartwich ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Stem Cells ◽  
Animal Model ◽  
Cancer Stem Cells ◽  
Ovarian Cancer Stem Cells ◽  
Resistant Animal
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