Microencapsulated Choroid Plexus Epithelial Cell Transplants for Repair of the Brain

2010 ◽  
pp. 80-91 ◽  
Author(s):  
Christopher G. Thanos ◽  
Briannan Bintz ◽  
Dwaine F. Emerich
Keyword(s):  
Epithelial Cell ◽  
Choroid Plexus ◽  
Choroid Plexus Epithelial Cell ◽  
Cell Transplants ◽  
The Brain ◽  
Choroid Plexus Epithelial

scholarly journals Expression of junctional proteins in choroid plexus epithelial cell lines: a comparative study

2007 ◽  
Vol 4 (1) ◽  
pp. 11 ◽  
Author(s):  
Joanna Szmydynger-Chodobska ◽  
Crissey L Pascale ◽  
Andrew N Pfeffer ◽  
Cassaundra Coulter ◽  
Adam Chodobski
Keyword(s):  
Epithelial Cell ◽  
Comparative Study ◽  
Choroid Plexus ◽  
Cell Lines ◽  
Choroid Plexus Epithelial Cell ◽  
Junctional Proteins ◽  
Epithelial Cell Lines ◽  
Choroid Plexus Epithelial

scholarly journals Fgf2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus epithelial cell behaviour

2008 ◽  
Vol 5 (1) ◽  
pp. 20 ◽  
Author(s):  
Sarah Greenwood ◽  
Adam Swetloff ◽  
Angela M Wade ◽  
Tetsuya Terasaki ◽  
Patrizia Ferretti
Keyword(s):  
Epithelial Cell ◽  
Choroid Plexus ◽  
Choroid Plexus Epithelial Cell ◽  
Cell Behaviour ◽  
Choroid Plexus Epithelial

Localization of Carbonic Anhydrase in the Rat Choroid Plexus Epithelial Cell

1984 ◽  
Vol 429 (1 Biology and C) ◽  
pp. 405-407 ◽  
Author(s):  
T. MASUZAWA ◽  
T. HASEGAWA ◽  
N. NAKAHARA ◽  
K. IIDA ◽  
F. SATO
Keyword(s):  
Epithelial Cell ◽  
Carbonic Anhydrase ◽  
Choroid Plexus ◽  
Choroid Plexus Epithelial Cell ◽  
Choroid Plexus Epithelial

scholarly journals Murine MPDZ-Linked Hydrocephalus is Caused by Hyperpermeability of the Choroid Plexus

2018 ◽  
Author(s):  
Junning Yang ◽  
Claire Simonneau ◽  
Robert Kilker ◽  
Laura Oakley ◽  
Matthew Byrne ◽  
...  
Keyword(s):  
Choroid Plexus ◽  
Protein Concentration ◽  
Cell Monolayer ◽  
Fold Increase ◽  
Loss Of Function ◽  
Choroid Plexus Epithelial Cell ◽  
Ultrastructural Evidence ◽  
The Brain ◽  
Severe Hydrocephalus ◽  
Choroid Plexus Epithelial

ABSTRACTThough congenital hydrocephalus is heritable, it has been linked only to eight genes, one of which is MPDZ. Humans and mice that carry a truncated version of MPDZ incur severe hydrocephalus resulting in acute morbidity and lethality. We show by magnetic resonance imaging that contrast-medium penetrates into the brain ventricles of mice carrying a Mpdz loss-of-function mutation, whereas none is detected in the ventricles of normal mice, implying that the permeability of the choroid plexus epithelial cell monolayer is abnormally high. Comparative proteomic analysis of the cerebrospinal fluid of normal and hydrocephalic mice revealed up to a 53-fold increase in protein concentration, suggesting that transcytosis through the choroid plexus epithelial cells of Mpdz KO mice is substantially higher than in normal mice. These conclusions are supported by ultrastructural evidence, and by immunohistochemistry and cytology data. Our results provide a straight-forward and concise explanation for the pathophysiology of Mpdz-linked hydrocephalus.

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