Studies of Mutagen-Activated Genes which Confer Anchorage-Independence: the c-sis Gene as a Model

1991 ◽  
pp. 35-46
Author(s):  
William E. Fahl ◽  
William H. Brondyk ◽  
Hua-Ming Jin ◽  
Craig W. Stevens ◽  
Carsten-Peter Carstens ◽  
...  
Keyword(s):  
Anchorage Independence

Transfer of anchorage independence by isolated metaphase chromosomes in hamster cells

Cell ◽  
1977 ◽  
Vol 12 (3) ◽  
pp. 675-682 ◽  
Author(s):  
Demetrios A. Spandidos ◽  
Louis Siminovitch
Keyword(s):  
Metaphase Chromosomes ◽  
Anchorage Independence

Estrogen-induced anchorage-independence in human endometrial stromal cells

1995 ◽  
Vol 62 (6) ◽  
pp. 772-776 ◽  
Author(s):  
Li-Hui Xu ◽  
Clifford A. Rinehart ◽  
David G. Kaufman
Keyword(s):  
Stromal Cells ◽  
Endometrial Stromal Cells ◽  
Anchorage Independence

Regional mapping of suppressor loci for anchorage independence and tumorigenicity on human chromosome 9

2001 ◽  
Vol 130 (2) ◽  
pp. 118-126 ◽  
Author(s):  
Lena K. Eklund ◽  
Khaleda Islam ◽  
Peter Söderkvist ◽  
M.Quamrul Islam
Keyword(s):  
Human Chromosome ◽  
Chromosome 9 ◽  
Regional Mapping ◽  
Anchorage Independence

Abstract B19: Functional genomics approach links anchorage-independence with tumor dormancy in ovarian cancer

2013 ◽  
Author(s):  
Noriomi Matsumura ◽  
Koji Yamanoi ◽  
Yasuaki Amano ◽  
Junzo Hamanishi ◽  
Tsukasa Baba ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Functional Genomics ◽  
Tumor Dormancy ◽  
Anchorage Independence

scholarly journals A transforming activity not detected by DNA transfer to NIH 3T3 cells is detected by JB6 mouse epidermal cells.

1985 ◽  
Vol 5 (4) ◽  
pp. 890-893 ◽  
Author(s):  
N H Colburn ◽  
M I Lerman ◽  
G A Hegamyer ◽  
T D Gindhart
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
3T3 Cells ◽  
Anchorage Independence ◽  
Transforming Activity ◽  
Mouse Epidermal Cell ◽  
Nih 3T3 ◽  
Transforming Genes ◽  
Nih 3T3 Cells

Transfection of four different mouse epidermal tumor cell DNAs into NIH 3T3 cells yielded neither morphologically altered foci nor anchorage independence. However, promotion-sensitive, but not promotion-insensitive, JB6 mouse epidermal cell lines were permissive for the expression of anchorage independence after transfection of DNA from three of these tumor cell lines. This transforming activity and the promotion-sensitive activity that confers sensitivity to promotion of transformation show differences in restriction enzyme sensitivity. In view of this difference and the differences in both recipient cells and 12-O-tetradecanoyl-phorbol-13-acetate dependence of expression, it appears that the transforming activity and the promotion-sensitive activity are specified by different genes. The JB6 promotion-sensitive cell lines may be useful for detecting and cloning transforming genes that escape detection in the NIH 3T3 cell focus assay.

Impairment of homologous recombination directed DNA repair in prostate cancer cells exposed to anchorage independence

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 9638-9638
Author(s):  
K. Reiss ◽  
J. Y. Wang ◽  
T. Ho ◽  
T. Stoklosa ◽  
T. Skorski ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dna Repair ◽  
Homologous Recombination ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Anchorage Independence
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