Splenic Glucocerebrosidase and Its Cytosolic Activator Protein: Effects on Substrate Hydrolysis and Covalent Inhibition by Conduritol B Epoxides

Lipid Storage Disorders ◽

10.1007/978-1-4613-1029-7_43 ◽

1988 ◽

pp. 353-358

Author(s):

Harald Liedtke ◽

Günter Legler

Keyword(s):

Activator Protein ◽

Covalent Inhibition ◽

Substrate Hydrolysis

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Cytokine synergy, collagenases and cartilage collagen breakdown

Biochemical Society Symposium ◽

10.1042/bss0700125 ◽

2003 ◽

Vol 70 ◽

pp. 125-133 ◽

Author(s):

Tim E. Cawston ◽

Jenny M. Milner ◽

Jon B. Catterall ◽

Andrew D. Rowan

Keyword(s):

Matrix Metalloproteinases ◽

Inflammatory Cytokines ◽

Activator Protein 1 ◽

Activator Protein ◽

And Cartilage ◽

Pro Inflammatory Cytokines

We have investigated proteinases that degrade cartilage collagen. We show that pro-inflammatory cytokines act synergistically with oncastatin M to promote cartilage collagen resorption by the up-regulation and activation of matrix metalloproteinases (MMPs). The precise mechanisms are not known, but involve the up-regulation of c-fos, which binds to MMP promoters at a proximal activator protein-1 (AP-1) site. This markedly up-regulates transcription and leads to higher levels of active MMP proteins.

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Activator protein-1 is necessary for angiotensin-II stimulation of human adrenocorticotropin receptor gene transcription

European Journal of Biochemistry ◽

10.1046/j.1432-1033.2001.02055.x ◽

2001 ◽

Vol 268 (6) ◽

pp. 1802-1810

Author(s):

Danielle Naville ◽

Estelle Bordet ◽

Marie-Claude Berthelon ◽

Philippe Durand ◽

Martine Begeot

Keyword(s):

Angiotensin Ii ◽

Gene Transcription ◽

Receptor Gene ◽

Activator Protein 1 ◽

Activator Protein ◽

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Die epigenetische Regulation von Transcription factor activator protein-2 epsilon (TFAP2E) führt via Dickkopf homolog 4 zur Chemoresistenz von 5-Fluoruracil beim kolorektalen Karzinom

Zeitschrift für Gastroenterologie ◽

10.1055/s-0030-1263599 ◽

2010 ◽

Vol 48 (08) ◽

Author(s):

M Tänzer ◽

B Balluff ◽

R Tetzner ◽

E Burgermeister ◽

A Reinacher Schick ◽

...

Keyword(s):

Transcription Factor ◽

Activator Protein ◽

Activator Protein 2

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Faculty Opinions recommendation of Structural basis for cAMP-mediated allosteric control of the catabolite activator protein.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1159419.619779 ◽

2009 ◽

Author(s):

Peter Artymiuk

Keyword(s):

Structural Basis ◽

Allosteric Control ◽

Catabolite Activator Protein ◽

Activator Protein

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Faculty Opinions recommendation of Gonadotropin-releasing hormone pulse sensitivity of follicle-stimulating hormone-beta gene is mediated by differential expression of positive regulatory activator protein 1 factors and corepressors SKIL and TGIF1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12586956.13825054 ◽

2011 ◽

Author(s):

Mone Zaidi ◽

Tony Yuen

Keyword(s):

Differential Expression ◽

Follicle Stimulating Hormone ◽

Gonadotropin Releasing Hormone ◽

Activator Protein 1 ◽

Releasing Hormone ◽

Activator Protein ◽

Beta Gene ◽

Stimulating Hormone

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Faculty Opinions recommendation of Nintedanib modulates surfactant protein-D expression in A549 human lung epithelial cells via the c-Jun N-terminal kinase-activator protein-1 pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727167063.793527367 ◽

2017 ◽

Author(s):

Martin Aringer

Keyword(s):

Epithelial Cells ◽

Surfactant Protein ◽

Lung Epithelial Cells ◽

Surfactant Protein D ◽

Activator Protein 1 ◽

Activator Protein ◽

Lung Epithelial ◽

Human Lung Epithelial Cells

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Faculty Opinions recommendation of A small GTPase activator protein interacts with cytoplasmic phytochromes in regulating root development.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8945956.9503054 ◽

2011 ◽

Author(s):

Tomomichi Fujita

Keyword(s):

Root Development ◽

Small Gtpase ◽

Activator Protein

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Catabolite Activator Protein

RCSB Protein Data Bank ◽

10.2210/rcsb_pdb/mom_2003_12 ◽

2003 ◽

Author(s):

D.S. Goodsell

Keyword(s):

Catabolite Activator Protein ◽

Activator Protein

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Roles of phosphatidylinositol 3-kinase regulatory subunit alpha, activator protein-1, and programmed cell death 4 in diagnosis of papillary thyroid carcinoma

Tumor Biology ◽

10.1007/s13277-015-4476-x ◽

2015 ◽

Vol 37 (5) ◽

pp. 6519-6526 ◽

Author(s):

Xiaojun Chen ◽

Wenjun Wu ◽

Xiong Chen ◽

Xiaohua Gong

Keyword(s):

Papillary Thyroid Carcinoma ◽

Programmed Cell Death ◽

Thyroid Carcinoma ◽

Regulatory Subunit ◽

Activator Protein 1 ◽

Papillary Thyroid ◽

Phosphatidylinositol 3 Kinase ◽

Activator Protein ◽

Programmed Cell Death 4

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Purification of catalytic subunit of low density lipoprotein receptor kinase and identification of heat-stable activator protein.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)48089-1 ◽

1987 ◽

Vol 262 (19) ◽

pp. 9367-9373 ◽

Author(s):

A Kishimoto ◽

J L Goldstein ◽

M S Brown

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Catalytic Subunit ◽

Low Density ◽

Lipoprotein Receptor ◽

Receptor Kinase ◽

Low Density Lipoprotein Receptor ◽

Activator Protein ◽

Heat Stable ◽

Density Lipoprotein Receptor

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