Effect of Produced Water on Innate Immunity, Feeding and Antioxidant Metabolism in Atlantic Cod (Gadus morhua)

2011 ◽  
pp. 311-328 ◽  
Author(s):  
Dounia Hamoutene ◽  
H. Volkoff ◽  
C. Parrish ◽  
S. Samuelson ◽  
G. Mabrouk ◽  
...  
2010 ◽  
Vol 70 (5) ◽  
pp. 383-394 ◽  
Author(s):  
Sonnich Meier ◽  
H. Craig Morton ◽  
Gunnar Nyhammer ◽  
Bjørn Einar Grøsvik ◽  
Valeri Makhotin ◽  
...  

2010 ◽  
Vol 70 (1) ◽  
pp. 26-34 ◽  
Author(s):  
Juan C. Pérez-Casanova ◽  
Dounia Hamoutene ◽  
Stephanie Samuelson ◽  
Kimberly Burt ◽  
Thomas L. King ◽  
...  

2010 ◽  
Vol 67 (10) ◽  
pp. 1685-1698 ◽  
Author(s):  
Tor Fredrik Holth ◽  
Anders Thorsen ◽  
Pål A. Olsvik ◽  
Ketil Hylland

Effects related to offshore contamination have been observed in gadoid species in the North Sea, but uncertainties regarding exposure conditions have led to the need for environmentally relevant exposure studies. In the current study, Atlantic cod ( Gadus morhua ) were sampled at regular intervals during an 11-month continuous or pulsed water-borne exposure to a mixture of produced water components. There was variation in time to female maturation between and within treatment groups; although differences were not significant, there was a tendency towards delayed maturation in intermittently exposed females not seen in continuously exposed females. Physiological parameters such as condition factor, liver somatic index, gonadosomatic index, or hematocrit did not appear to be affected by the treatments. A range of toxicologically relevant genes were differentially expressed in the exposed fish, including AhR-responsive genes (CYP1A, UDP-GT) and genes relevant to immune function (complement C3, MHC 1, CYP27B), apoptosis (PERP), and oxidative stress (hepcidin, serotransferrin, glutathione peroxidase). Although powerful in their depiction of the complexity of cellular responses to environmental stressors, the use of molecular tools should be accompanied by biochemical and physiological endpoints, and results should be holistically interpreted in terms of individual health and function.


2011 ◽  
Vol 74 (7-9) ◽  
pp. 555-568 ◽  
Author(s):  
T. F. Holth ◽  
B. A. Beylich ◽  
L. Camus ◽  
G. I. V. Klobučar ◽  
K. Hylland

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