scholarly journals Lipoxygenase-Catalysed Oxidation of Linoleic Acid

Author(s):  
Johannes F. G. Vliegenthart ◽  
Gerrit A. Veldink
2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.


1976 ◽  
Vol 73 ◽  
pp. 283-286 ◽  
Author(s):  
H. S. Singh ◽  
A. K. Sisodia ◽  
S. M. Singh ◽  
R. K. Singh ◽  
R. N. Singh

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
C Wawrzenczyk ◽  
B Tubek ◽  
P Mitula ◽  
K Kempinska ◽  
J Wietrzyk

Pneumologie ◽  
2016 ◽  
Vol 70 (07) ◽  
Author(s):  
N Aggarwal ◽  
S Wrenger ◽  
V Grau ◽  
T Welte ◽  
S Janciauskiene

2004 ◽  
Vol 51 (5) ◽  
pp. 481
Author(s):  
Hak Jin Kim ◽  
Chang Hun Lee ◽  
Yong Seon Pyun ◽  
Tea Hong Lee

2011 ◽  
Vol 3 (5) ◽  
pp. 585-588
Author(s):  
B Dharma Rao B Dharma Rao ◽  
◽  
M Sridevi M Sridevi ◽  
P Vani P Vani

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