Lipopigments in Veterinary Pathology: Pathogenesis and Terminology

1990 ◽  
pp. 157-168 ◽  
Author(s):  
R. D. Jolly ◽  
R. R. Dalefield
Keyword(s):  
Veterinary Pathology

scholarly journals Extracellular Vesicles: Novel Opportunities to Understand and Detect Neoplastic Diseases

2021 ◽  
pp. 030098582199932
Author(s):  
Laura Bongiovanni ◽  
Anneloes Andriessen ◽  
Marca H. M. Wauben ◽  
Esther N. M. Nolte-’t Hoen ◽  
Alain de Bruin
Keyword(s):  
Extracellular Vesicles ◽  
Biologically Active ◽  
Liquid Biopsies ◽  
Donor Cells ◽  
Recent Developments ◽  
Veterinary Pathology ◽  
Cell Components ◽  
Potential Applications ◽  
Intercellular Communications

With a size range from 30 to 1000 nm, extracellular vesicles (EVs) are one of the smallest cell components able to transport biologically active molecules. They mediate intercellular communications and play a fundamental role in the maintenance of tissue homeostasis and pathogenesis in several types of diseases. In particular, EVs actively contribute to cancer initiation and progression, and there is emerging understanding of their role in creation of the metastatic niche. This fact underlies the recent exponential growth in EV research, which has improved our understanding of their specific roles in disease and their potential applications in diagnosis and therapy. EVs and their biomolecular cargo reflect the state of the diseased donor cells, and can be detected in body fluids and exploited as biomarkers in cancer and other diseases. Relatively few studies have been published on EVs in the veterinary field. This review provides an overview of the features and biology of EVs as well as recent developments in EV research including techniques for isolation and analysis, and will address the way in which the EVs released by diseased tissues can be studied and exploited in the field of veterinary pathology. Uniquely, this review emphasizes the important contribution that pathologists can make to the field of EV research: pathologists can help EV scientists in studying and confirming the role of EVs and their molecular cargo in diseased tissues and as biomarkers in liquid biopsies.

Business intelligence tools to optimize the appropriateness of the diagnostic process for clinical and epidemiologic purposes in a multicenter veterinary pathology service

2021 ◽  
pp. 104063872110031
Author(s):  
Nicola Pozzato ◽  
Laura D’Este ◽  
Laura Gagliazzo ◽  
Marta Vascellari ◽  
Monia Cocchi ◽  
...  
Keyword(s):  
Business Intelligence ◽  
Reporting System ◽  
Animal Health ◽  
Final Diagnosis ◽  
Information Management System ◽  
Daily Basis ◽  
Diagnostic Process ◽  
Multifactorial Diseases ◽  
Specific Syndrome ◽  
Veterinary Pathology

Laboratory tests provide essential support to the veterinary practitioner, and their use has grown exponentially. This growth is the result of several factors, such as the eradication of historical diseases, the occurrence of multifactorial diseases, and the obligation to control endemic and epidemic diseases. However, the introduction of novel techniques is counterbalanced by economic constraints, and the establishment of evidence- and consensus-based guidelines is essential to support the pathologist. Therefore, we developed standardized protocols, categorized by species, type of production, age, and syndrome at the Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), a multicenter institution for animal health and food safety. We have 72 protocols in use for livestock, poultry, and pets, categorized as, for example, “bovine enteric calf”, “rabbit respiratory”, “broiler articular”. Each protocol consists of a panel of tests, divided into ‘mandatory’ and ‘ancillary’, to be selected by the pathologist in order to reach the final diagnosis. After autopsy, the case is categorized into a specific syndrome, subsequently referred to as a syndrome-specific panel of analyses. The activity of the laboratories is monitored through a web-based dynamic reporting system developed using a business intelligence product (QlikView) connected to the laboratory information management system (IZILAB). On a daily basis, reports become available at general, laboratory, and case levels, and are updated as needed. The reporting system highlights epidemiologic variations in the field and allows verification of compliance with the protocols within the organization. The diagnostic protocols are revised annually to increase system efficiency and to address stakeholder requests.

A Short History of the Origins of the European Society of Veterinary Pathology in the Arbeitsgemeinschaft der Veterinärpathologen

2021 ◽  
pp. 030098582110021
Author(s):  
Andreas Pospischil ◽  
Walter Hermanns
Keyword(s):  
European Society ◽  
The United States ◽  
European Countries ◽  
Short History ◽  
Parent Organization ◽  
National Organizations ◽  
Veterinary Pathology ◽  
History Of ◽  
European College ◽  
Pathologische Anatomie

The first continental European association for veterinary pathologists was founded in 1951 as the Arbeitsgemeinschaft der Veterinärpathologen (AG-Vetpath), bringing together veterinary pathologists from Germany, several European countries, and the United States. Yearly meetings were held in conjunction with the Deutsche Gesellschaft für Pathologie (DGP). Although the majority of DGP members were human pathologists, veterinary pathologists had been using the DGP as a forum for scientific exchange since the early 20th century. Renamed in 1969 as the Europäische Arbeitsgemeinschaft für Veterinärpathologen, and in 1974 as the Europäische Gesellschaft für Veterinärpathologie, the AG-Vetpath finally received its present name, the European Society for Veterinary Pathology (ESVP) in 1994. In parallel, national organizations for veterinary pathologists in European countries have also evolved over the years, the earliest being in Germany with the Fachgruppe Allgemeine Pathologie und pathologische Anatomie of the Deutsche Veterinärmedizinische Gesellschaft (DVG). AG-Vetpath represents the parent organization for further specialty organizations like the Gesellschaft für Toxikologische Pathologie (GTP) or the Arbeitskreis Diagnostische Veterinärpathologie (AKDV). Even the European College of Veterinary Pathologists (ECVP) was founded by members of ESVP.

Diagnostic Challenge in Veterinary Pathology: Alopecic Crusting Dermatitis in a Goat

2021 ◽  
pp. 030098582110626
Author(s):  
Jason D. Struthers ◽  
Clemence Chako ◽  
Stephani Ruppert ◽  
Kenneth Jackson ◽  
Patricia A. Pesavento
Keyword(s):  
Diagnostic Challenge ◽  
Veterinary Pathology

scholarly journals Causes of spontaneous death and euthanasia in dogs: A background study in Bahia, Brazil

2021 ◽  
Vol 66 (No. 4) ◽  
pp. 156-166
Author(s):  
JL Freitas ◽  
TS Andrade ◽  
ES Martins Filho ◽  
CS D’Soares ◽  
ACSN Souza ◽  
...  
Keyword(s):  
Death Rate ◽  
Northeast Brazil ◽  
Disease Category ◽  
Pathology Laboratory ◽  
High Death Rate ◽  
High Death ◽  
Veterinary Pathology ◽  
Diagnostic Capabilities ◽  
Health Programmes ◽  
Epidemiological Information

Understanding the causes of death in dogs enhances the diagnostic capabilities of veterinarians, as well as reduces animal mortality. Studies on this topic assist in the control and prophylaxis of epidemics and in structuring public health programmes. In total, 1 355 necropsy reports of dogs filed at the Veterinary Pathology Laboratory of the Federal University of Bahia, Northeast, Brazil (2005–2017) were analysed. The epidemiological information and anatomopathological diagnoses were obtained. The diagnosed diseases were classified into 10 categories. The frequency of the zoonoses, the overall age of the death (AD) of the dogs, and the AD of the dogs for each disease category were determined. Infectious and parasitic diseases were the most frequent primary causes of death in puppies (44.62%) and adult dogs (26.52%). In elderly dogs, most deaths occurred due to neoplasms (42.37%). Distemper (10.46%) was the most prevalent condition. A high frequency of zoonoses (6.12%) and a high death rate caused by diseases that could have been prevented (15.06%), such as distemper, parvovirus and canine visceral leishmaniasis, were reported. The AD in the population studied was eight years. The results confirmed the hypothesis of a high death rate in dogs in the state of Bahia, Northeast, Brazil, because of preventable infectious diseases.

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