Purification and Characterization of Mouse Olfactory Ensheathing Cells and Their Potential Use for Therapy in Amyotrophic Lateral Sclerosis (ALS)

2015 ◽  
pp. 195-208
Author(s):  
Chrystian Junqueira Alves ◽  
Alexandre Baldasserini Guimarães ◽  
Jessica Ruivo Maximino ◽  
Sergio Paulo Bydlowski ◽  
Gerson Chadi
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Olfactory Ensheathing Cells ◽  
Purification And Characterization ◽  
Ensheathing Cells ◽  
Potential Use ◽  
Lateral Sclerosis

Fetal olfactory ensheathing cells transplantation in amyotrophic lateral sclerosis patients: a controlled pilot study

2008 ◽  
Vol 22 (6) ◽  
pp. 710-718 ◽  
Author(s):  
Hongyun Huang ◽  
Lin Chen ◽  
Haitao Xi ◽  
Hongmei Wang ◽  
Jian Zhang ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Pilot Study ◽  
Olfactory Ensheathing Cells ◽  
Ensheathing Cells ◽  
Lateral Sclerosis

scholarly journals RNA Deregulation in Amyotrophic Lateral Sclerosis: The Noncoding Perspective

2021 ◽  
Vol 22 (19) ◽  
pp. 10285
Author(s):  
Pietro Laneve ◽  
Paolo Tollis ◽  
Elisa Caffarelli
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Potential Role ◽  
Noncoding Rnas ◽  
Rna Metabolism ◽  
Biological Processes ◽  
Diagnostic Biomarkers ◽  
Defective Rna ◽  
Almost All ◽  
Lateral Sclerosis

RNA metabolism is central to cellular physiopathology. Almost all the molecular pathways underpinning biological processes are affected by the events governing the RNA life cycle, ranging from transcription to degradation. The deregulation of these processes contributes to the onset and progression of human diseases. In recent decades, considerable efforts have been devoted to the characterization of noncoding RNAs (ncRNAs) and to the study of their role in the homeostasis of the nervous system (NS), where they are highly enriched. Acting as major regulators of gene expression, ncRNAs orchestrate all the steps of the differentiation programs, participate in the mechanisms underlying neural functions, and are crucially implicated in the development of neuronal pathologies, among which are neurodegenerative diseases. This review aims to explore the link between ncRNA dysregulation and amyotrophic lateral sclerosis (ALS), the most frequent motoneuron (MN) disorder in adults. Notably, defective RNA metabolism is known to be largely associated with this pathology, which is often regarded as an RNA disease. We also discuss the potential role that these transcripts may play as diagnostic biomarkers and therapeutic targets.

Immunocytochemical characterization of olfactory ensheathing cells in fish

2012 ◽  
Vol 218 (2) ◽  
pp. 539-549 ◽  
Author(s):  
Maurizio Lazzari ◽  
Simone Bettini ◽  
Valeria Franceschini
Keyword(s):  
Olfactory Ensheathing Cells ◽  
Ensheathing Cells

scholarly journals Characterization of FUS Mutations in Amyotrophic Lateral Sclerosis Using RNA-Seq

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e60788 ◽  
Author(s):  
Marka van Blitterswijk ◽  
Eric T. Wang ◽  
Brad A. Friedman ◽  
Pamela J. Keagle ◽  
Patrick Lowe ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Rna Seq ◽  
Lateral Sclerosis

Identification and characterization of novel and rare susceptible variants in Indian amyotrophic lateral sclerosis patients

Neurogenetics ◽  
2019 ◽  
Vol 20 (4) ◽  
pp. 197-208 ◽  
Author(s):  
Priyam Narain ◽  
Aditya K. Padhi ◽  
Upma Dave ◽  
Dibyakanti Mishra ◽  
Rohit Bhatia ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Identification And Characterization ◽  
Lateral Sclerosis
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