Cancer Drug Resistance: A Brief Overview from a Genetic Viewpoint

2016 ◽  
pp. 1-18 ◽  
Author(s):  
José Rueff ◽  
António Sebastião Rodrigues
Keyword(s):  
Drug Resistance ◽  
Cancer Drug ◽  
Cancer Drug Resistance

Fanconi Anemia DNA Repair Pathway as a New Mechanism to Exploit Cancer Drug Resistance

2020 ◽  
Vol 20 (9) ◽  
pp. 779-787
Author(s):  
Kajal Ghosal ◽  
Christian Agatemor ◽  
Richard I. Han ◽  
Amy T. Ku ◽  
Sabu Thomas ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Dna Repair ◽  
Fanconi Anemia ◽  
Cancer Drug ◽  
Drug Resistant ◽  
Cancer Drugs ◽  
Repair Pathway ◽  
Cancer Drug Resistance ◽  
Anti Cancer ◽  
Cancerous Cells

Chemotherapy employs anti-cancer drugs to stop the growth of cancerous cells, but one common obstacle to the success is the development of chemoresistance, which leads to failure of the previously effective anti-cancer drugs. Resistance arises from different mechanistic pathways, and in this critical review, we focus on the Fanconi Anemia (FA) pathway in chemoresistance. This pathway has yet to be intensively researched by mainstream cancer researchers. This review aims to inspire a new thrust toward the contribution of the FA pathway to drug resistance in cancer. We believe an indepth understanding of this pathway will open new frontiers to effectively treat drug-resistant cancer.

Understanding Cancer Drug Resistance by Developing and Studying Resistant Cell Line Models

2016 ◽  
Vol 16 (3) ◽  
pp. 226-237 ◽  
Author(s):  
Cristina P.R. Xavier ◽  
Milica Pesic ◽  
M. Helena Vasconcelos
Keyword(s):  
Drug Resistance ◽  
Cell Line ◽  
Resistant Cell ◽  
Resistant Cell Line ◽  
Cancer Drug ◽  
Cancer Drug Resistance

scholarly journals Recent Progress in Characterizing Long Noncoding RNAs in Cancer Drug Resistance

2019 ◽  
Vol 10 (26) ◽  
pp. 6693-6702 ◽  
Author(s):  
Wenyuan Zhao ◽  
Bin Shan ◽  
Dan He ◽  
Yuanda Cheng ◽  
Bin Li ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Recent Progress ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Cancer Drug ◽  
Cancer Drug Resistance

Nanoparticle-based drug delivery systems with platinum drugs for overcoming cancer drug resistance

2021 ◽  
Author(s):  
Peng Xie ◽  
Yushu Wang ◽  
Dengshuai Wei ◽  
Lingpu Zhang ◽  
Bin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Cancer Drug ◽  
Platinum Drugs ◽  
Effective Strategy ◽  
Platinum Drug ◽  
Cancer Drug Resistance ◽  
Platinum Drug Resistance

The mechanisms of chemoresistance and nanoparticle-based drug delivery systems for platinum drugs were detailed summarized in this review. The current combination therapy provided an effective strategy to overcome the platinum drug resistance.

scholarly journals Correction to Overcoming Ovarian Cancer Drug Resistance with a Cold Responsive Nanomaterial

2021 ◽  
Author(s):  
Hai Wang ◽  
Pranay Agarwal ◽  
Gang Zhao ◽  
Guang Ji ◽  
Christopher M. Jewell ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Drug Resistance ◽  
Cancer Drug ◽  
Cancer Drug Resistance

Long non-coding RNAs in cancer drug resistance development

DNA Repair ◽  
2016 ◽  
Vol 45 ◽  
pp. 25-33 ◽  
Author(s):  
Maryam Majidinia ◽  
Bahman Yousefi
Keyword(s):  
Drug Resistance ◽  
Cancer Drug ◽  
Resistance Development ◽  
Cancer Drug Resistance ◽  
Non Coding Rnas
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