scholarly journals Zebrafish Model of the Blood-Brain Barrier: Morphological and Permeability Studies

2010 ◽  
pp. 371-378 ◽  
Author(s):  
Brian P. Eliceiri ◽  
Ana Maria Gonzalez ◽  
Andrew Baird
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Zebrafish Model ◽  
Blood Brain ◽  
Permeability Studies

Permeability Studies on In Vitro Blood–Brain Barrier Models: Physiology, Pathology, and Pharmacology

2005 ◽  
Vol 25 (1) ◽  
pp. 59-127 ◽  
Author(s):  
Mária A. Deli ◽  
Csongor S. Ábrahám ◽  
Yasufumi Kataoka ◽  
Masami Niwa
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Blood Brain ◽  
Permeability Studies

scholarly journals Clostridium perfringens Epsilon Toxin Compromises the Blood-Brain Barrier in a Humanized Zebrafish Model

iScience ◽  
2019 ◽  
Vol 15 ◽  
pp. 39-54
Author(s):  
Drew Adler ◽  
Jennifer R. Linden ◽  
Samantha V. Shetty ◽  
Yinghua Ma ◽  
Monika Bokori-Brown ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Clostridium Perfringens ◽  
Brain Barrier ◽  
Zebrafish Model ◽  
Blood Brain ◽  
Epsilon Toxin

scholarly journals Crossing the blood–brain–barrier with transferrin conjugated carbon dots: A zebrafish model study

2016 ◽  
Vol 145 ◽  
pp. 251-256 ◽  
Author(s):  
Shanghao Li ◽  
Zhili Peng ◽  
Julia Dallman ◽  
James Baker ◽  
Abdelhameed M. Othman ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Carbon Dots ◽  
Brain Barrier ◽  
Zebrafish Model ◽  
Blood Brain ◽  
Model Study

scholarly journals Hyperosmolar Opening of the Blood-Brain Barrier in the Energy-Depleted Rat Brain. Part 1. Permeability Studies

1988 ◽  
Vol 8 (1) ◽  
pp. 9-15 ◽  
Author(s):  
J. Greenwood ◽  
P. J. Luthert ◽  
O. E. Pratt ◽  
P. L. Lantos
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Surrounding Tissue ◽  
Control Value ◽  
A Value ◽  
Blood Brain ◽  
Hyperosmolar Solutions ◽  
Barrier Opening ◽  
Permeability Studies ◽  
The Brain

A simple saline perfusion system was used to investigate the effects of hyperosmolar solutions of arabinose and mannitol upon the permeability of the blood-brain barrier. The small, polar molecule [14C]mannitol and the larger, visual marker Evans blue were used as indicators of barrier integrity in the perfused energydepleted brain. One-minute perfusion of hyperosmolar solutions consistently opened the barrier suggesting that the mechanism of osmotic barrier opening is independent of energy-producing metabolism. The accumulation of radiolabel in the brain was expressed as the ratio of tissue to perfusate radioactivity ( Rt/ Rp) and, for cerebrum, this increased from a control value of 0.0022 ± 0.0007 (mean ± SEM; n = 4) to a value of 0.0124 ± 0.0008 (n = 4) following 0.9 M arabinose and to 0.0495 ± 0.0072 (n = 4) following 1.8 M arabinose. There was a significant reduction of water content of hyperosmolar perfused brains. These findings support the hypothesis that osmotic barrier opening is the result of the passive shrinkage of endothelial cells and the surrounding tissue.

scholarly journals Transferrin Functionalized Liposomes Loading Dopamine HCl: Development and Permeability Studies across an In Vitro Model of Human Blood–Brain Barrier

Nanomaterials ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. 178 ◽  
Author(s):  
Antonio Lopalco ◽  
Annalisa Cutrignelli ◽  
Nunzio Denora ◽  
Angela Lopedota ◽  
Massimo Franco ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Human Blood ◽  
In Vitro Model ◽  
Brain Barrier ◽  
Blood Brain ◽  
Vitro Model ◽  
Permeability Studies

scholarly journals The rights and wrongs of blood-brain barrier permeability studies: a walk through 100 years of history

2014 ◽  
Vol 8 ◽  
Author(s):  
Norman R. Saunders ◽  
Jean-Jacques Dreifuss ◽  
Katarzyna M. Dziegielewska ◽  
Pia A. Johansson ◽  
Mark D. Habgood ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Blood Brain ◽  
Brain Barrier Permeability ◽  
Permeability Studies
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