Culturing and Expansion of “Clinical Grade” Precursors Cells from the Fetal Human Central Nervous System

2013 ◽  
pp. 65-77 ◽  
Author(s):  
Maurizio Gelati ◽  
Daniela Profico ◽  
Massimo Projetti-Pensi ◽  
Gianmarco Muzi ◽  
Giada Sgaravizzi ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Grade ◽  
Human Central Nervous System

Sex Differences in Cognition

2019 ◽  
pp. 41-66
Author(s):  
Elizabeth Hampson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sex Differences ◽  
Spatial Cognition ◽  
Sex Steroids ◽  
Cognitive Functions ◽  
Laboratory Animals ◽  
Human Central Nervous System ◽  
The Brain

Organizational and activational effects of sex steroids were first discovered in laboratory animals, but these concepts extend to hormonal actions in the human central nervous system. This chapter begins with a brief overview of how sex steroids act in the brain and how the organizational-activational hypothesis originated in the field of endocrinology. It then reviews common methods used to study these effects in humans. Interestingly, certain cognitive functions appear to be subject to modification by sex steroids, and these endocrine influences may help explain the sex differences often seen in these functions. The chapter considers spatial cognition as a representative example because the spatial family of functions has received the most study by researchers interested in the biological roots of sex differences in cognition. The chapter reviews evidence that supports an influence of both androgens and estrogens on spatial functions, and concludes with a glimpse of where the field is headed.

Humoral immune responses within the human central nervous system following systemic immunization

1986 ◽  
Vol 11 (3) ◽  
pp. 205-214 ◽  
Author(s):  
Magnhild Sandberg-Wollheim ◽  
Burton Zweiman ◽  
Arnold I. Levinson ◽  
Robert P. Lisak
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Immune Responses ◽  
Human Central Nervous System ◽  
Humoral Immune ◽  
Humoral Immune Responses

Simulations of Synaptic Transmission Using Lattice Boltzmann Methods

2002 ◽  
Author(s):  
Mehrak Mahmoudi ◽  
Piroz Zamankhan ◽  
William Polashenski
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Theoretical Model ◽  
Lattice Boltzmann ◽  
Chemical Substance ◽  
Human Central Nervous System ◽  
Lattice Boltzmann Methods ◽  
Nerve Impulses ◽  
System A ◽  
The Central Nervous System

The nervous system remains one of the least understood biological structures due in large part to the enormous complexity of this organ. A theoretical model for the transfer of nerve impulses would be valuable for the analysis of various phenomena in the nervous system, which are difficult to study by experiments. The central nervous system is composed of more than 100 billion neurons, through which information is transmitted via nerve impulses. Nerve impulses are not immediately apparent since each impulse may be blocked during transmission, changed from a single impulse into repetitive impulse, or integrated with impulses from other neurons to form highly intricate patterns. In the human central nervous system, a neuron secretes a chemical substance called a neurotransmitter at the synapse, and this transmitter in turn acts on another neuron to cause excitation, inhibition, or some other modification of its sensitivity.

MYELIN CONSTITUENTS OF HUMAN CENTRAL NERVOUS SYSTEM

1970 ◽  
Vol 46 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Jørgen Clausen ◽  
Inge Berg Hansen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Human Central Nervous System

Expression of NF2-encoded Merlin and Related ERM Family Proteins in the Human Central Nervous System

1997 ◽  
Vol 56 (6) ◽  
pp. 735-742 ◽  
Author(s):  
Anat O. Stemmer-Rachamimov ◽  
Charo Gonzalez-Agosti ◽  
Lin Xu ◽  
Jennifer A. Burwick ◽  
Roberta Beauchamp ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Human Central Nervous System

Transplantation of human central nervous system stem cells - neuroprotection in retinal degeneration

2012 ◽  
Vol 35 (3) ◽  
pp. 468-477 ◽  
Author(s):  
Trevor J. McGill ◽  
Benjamin Cottam ◽  
Bin Lu ◽  
Shaomei Wang ◽  
Sergej Girman ◽  
...  
Keyword(s):  
Stem Cells ◽  
Central Nervous System ◽  
Nervous System ◽  
Retinal Degeneration ◽  
Human Central Nervous System

scholarly journals Evaluation of an enzyme immunoassay for clinical diagnosis of neurocysticercosis in symptomatic patients

2010 ◽  
Vol 43 (6) ◽  
pp. 647-650 ◽  
Author(s):  
Reynaldo Mendes de Carvalho Junior ◽  
Dorcas Lamounier Costa ◽  
Savyo Carvalho Soares ◽  
Carlos Henrique Nery Costa
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Sensitivity And Specificity ◽  
Cerebral Spinal Fluid ◽  
Taenia Solium ◽  
Enzyme Linked Immunosorbent Assay ◽  
Parasitic Disease ◽  
Multivariate Logistic Regression ◽  
Human Central Nervous System ◽  
Elisa Kit

INTRODUCTION: Neurocysticercosis is an infection of the human central nervous system caused by the metacestode larvae of Taenia solium. Neurocysticercosis is the most common parasitic disease in developing countries. Epilepsy is the most common clinical manifestation. Difficulties in confirming the diagnosis motivated the evaluation of the enzyme-linked immunosorbent assay on cerebral spinal fluid (CSF). METHODS: Twenty-two patients with NCC and 44 control patients were studied. CSF was analyzed using a commercial ELISA kit developed for NCC. Sensitivity and specificity were measured and a multivariate logistic regression was performed. RESULTS: Sensitivity and specificity of ELISA were 31.8% and 100%, respectively, with accuracy of 77.3%. Only the size of the lesions proved to be important for performance of the test. CONCLUSIONS: The results showed that ELISA contributes to the diagnosis of neurocysticercosis if the result is negative or if the patient has a lesion of 2 cm or more.

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