Heat Transfer Laws on Temperature Distribution in Biological Tissues

2021 ◽  
Vol 11 (17) ◽  
pp. 8271 ◽  
Author(s):  
Cheng Chen ◽  
Ming-An Yu ◽  
Lin Qiu ◽  
Hong-Yu Chen ◽  
Zhen-Long Zhao ◽  
...  

(1) Background: Microwave ablation (MWA) is a common tumor ablation surgery. Because of the high temperature of the ablation antenna, it is strongly destructive to surrounding vital tissues, resulting in high professional requirements for clinicians. The method used to carry out temperature observation and damage prediction in MWA is significant; (2) Methods: This work employs numerical study to explore temperature distribution of typical tissues in MWA. Firstly, clinical MWA based on isolated biological tissue is implemented. Then, the Pennes models and microwave radiation physics are established based on experimental parameters and existing related research. Initial values and boundary conditions are adjusted to better meet the real clinical materials and experimental conditions. Finally, clinical MWA data test this model. On the premise that the model is matched with clinical MWA, fat and bone are deduced for further heat transfer analysis. (3) Results: Numerical study obtains the temperature distribution of biological tissue in MWA. It observes the heat transfer law of ablation antenna in biological tissue. Additionally, combined with temperature threshold, it generates thermal damage of biological tissues and predicts the possible risks in MWA; (4) Conclusions: This work proposes a numerical study of typical biological tissues. It provides a new theoretical basis for clinically thermal ablation surgery.


2011 ◽  
Vol 675-677 ◽  
pp. 987-990
Author(s):  
Ling Tang ◽  
Xu Dong Wang ◽  
Hai Jing Zhao ◽  
Man Yao

In this paper, the flow, heat transfer and stress during solidification process of the machine tool bed weighed about 2.5ton that has been optimized by structural topologymethod, was calculated with ProCAST software, and the causes of the crack forming in the casting of the machine tool bed was analysed. According to the calculation results, the structural design of the local part where cracks tends to form has been improved, and the heat transfer and the stress are calculated again. By comparing the temperature field with filling of molten cast iron and without filling, it has been found that there was little effect of filling on the results of temperature distribution of the cast, therefore the effect of filling can be ignored in the following temperature field calculation to save computation time. The model has been simplified in the stress field calculation with considering the complexity of the machine tool bed and the cost of computation. Then, the merits and demerits of the original design and the improved design are compared and analyzed depending on the calculated temperature and stress results. It is suggested that the improved one could get a more uniform temperature distribution and then the trend of the crack occurring can be greatly reduced. These results could provide a guide for the actual casting production, achieving the scientific control of the production of castings, ensuring the quality of the castings.


Author(s):  
Si-Hwa Jeong ◽  
Min-Gu Won ◽  
Nam-Su Huh ◽  
Yun-Jae Kim ◽  
Young-Jin Oh ◽  
...  

In this paper, the thermal stress characteristics of the pipe-in-pipe (PIP) system under high temperature condition are analyzed. The PIP is a type of pipe applied in sodium-cooled faster reactor (SFR) and has a different geometry from a single pipe. In particular, under the high temperature condition of the SFR, the high thermal stress is generated due to the temperature gradient occurring between the inner pipe and outer pipe. To investigate the thermal stress characteristics, three cases are considered according to geometry of the support. The fully constrained support and intermediate support are considered for case 1 and 2, respectively. For case 3, both supports are applied to the actual curved pipe. The finite element (FE) analyses are performed in two steps for each case. Firstly, the heat transfer analysis is carried out considering the thermal conduction, convection and radiation conditions. From the heat transfer analysis, the temperature distribution results in the piping system are obtained. Secondly, the structural analysis is performed considering the temperature distribution results and boundary conditions. Finally, the effects of the geometric characteristics on the thermal stress in the PIP system are analyzed.


Author(s):  
Junnosuke Okajima ◽  
Atsuki Komiya ◽  
Shigenao Maruyama

The objective of this work is to experimentally and numerically evaluate small-scale cryosurgery using an ultrafine cryoprobe. The outer diameter (OD) of the cryoprobe was 550 μm. The cooling performance of the cryoprobe was tested with a freezing experiment using hydrogel at 37 °C. As a result of 1 min of cooling, the surface temperature of the cryoprobe reached −35 °C and the radius of the frozen region was 2 mm. To evaluate the temperature distribution, a numerical simulation was conducted. The temperature distribution in the frozen region and the heat transfer coefficient was discussed.


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